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Clinical decision support systems require models that are not only highly accurate but also equitable and sensitive to the implications of missed diagnoses. In this study, we introduce a knowledge-guided in-context learning (ICL) framework…

机器学习 · 计算机科学 2025-07-28 Fatemeh Nazary , Yashar Deldjoo , Tommaso Di Noia , Eugenio di Sciascio

The adoption of large language models (LLMs) to assist clinicians has attracted remarkable attention. Existing works mainly adopt the close-ended question-answering (QA) task with answer options for evaluation. However, many clinical…

The integration of Artificial Intelligence (AI), especially Large Language Models (LLMs), into the clinical diagnosis process offers significant potential to improve the efficiency and accessibility of medical care. While LLMs have shown…

计算与语言 · 计算机科学 2024-10-15 Mingyu Derek Ma , Chenchen Ye , Yu Yan , Xiaoxuan Wang , Peipei Ping , Timothy S Chang , Wei Wang

Medical reports contain rich clinical information but are often unstructured and written in domain-specific language, posing challenges for information extraction. While proprietary large language models (LLMs) have shown promise in…

计算与语言 · 计算机科学 2026-03-12 Luc Builtjes , Joeran Bosma , Mathias Prokop , Bram van Ginneken , Alessa Hering

The inherent complexity of structured longitudinal Electronic Health Records (EHR) data poses a significant challenge when integrated with Large Language Models (LLMs), which are traditionally tailored for natural language processing.…

计算与语言 · 计算机科学 2024-02-13 Yinghao Zhu , Zixiang Wang , Junyi Gao , Yuning Tong , Jingkun An , Weibin Liao , Ewen M. Harrison , Liantao Ma , Chengwei Pan

Large language models (LLMs) are increasingly used to extract structured information from free-text clinical records, but prior work often focuses on single tasks, limited models, and English-language reports. We evaluated 15 open-weight…

Doctors and patients alike increasingly use Large Language Models (LLMs) to diagnose clinical cases. However, unlike domains such as math or coding, where correctness can be objectively defined by the final answer, medical diagnosis…

Medical concept extraction from electronic health records underpins many downstream applications, yet remains challenging because medically meaningful concepts are frequently implied rather than explicitly stated in medical narratives.…

计算与语言 · 计算机科学 2026-05-21 Zhichao Yang , Gregory D. Lyng , Sanjit Singh Batra , Robert E. Tillman

Natural language processing (NLP) is a key technology to extract important patient information from clinical narratives to support healthcare applications. The rapid development of large language models (LLMs) has revolutionized many NLP…

计算与语言 · 计算机科学 2025-09-08 Cheng Peng , Xinyu Dong , Mengxian Lyu , Daniel Paredes , Yaoyun Zhang , Yonghui Wu

Information Extraction (IE) is an essential task in Natural Language Processing. Traditional methods have relied on coarse-grained extraction with simple instructions. However, with the emergence of Large Language Models (LLMs), there is a…

计算与语言 · 计算机科学 2023-10-10 Jun Gao , Huan Zhao , Yice Zhang , Wei Wang , Changlong Yu , Ruifeng Xu

Large Language Models (LLMs) are increasingly deployed in medicine. However, their utility in non-generative clinical prediction, often presumed inferior to specialized models, remains under-evaluated, leading to ongoing debate within the…

Large language models (LLMs) have shown remarkable capabilities in Natural Language Processing (NLP), especially in domains where labeled data is scarce or expensive, such as clinical domain. However, to unlock the clinical knowledge hidden…

计算与语言 · 计算机科学 2023-09-18 Sonish Sivarajkumar , Mark Kelley , Alyssa Samolyk-Mazzanti , Shyam Visweswaran , Yanshan Wang

Large Language Models (LLMs) have made remarkable strides in various tasks. Whether LLMs are competitive few-shot solvers for information extraction (IE) tasks, however, remains an open problem. In this work, we aim to provide a thorough…

计算与语言 · 计算机科学 2024-04-15 Yubo Ma , Yixin Cao , YongChing Hong , Aixin Sun

Rare diseases affect hundreds of millions worldwide, yet diagnosis often spans years. Convectional pipelines decouple noisy evidence extraction from downstream inferential diagnosis, and general/medical large language models (LLMs) face…

We present LLMStructBench, a novel benchmark for evaluating Large Language Models (LLMs) on extracting structured data and generating valid JavaScript Object Notation (JSON) outputs from natural-language text. Our open dataset comprises…

计算与语言 · 计算机科学 2026-02-17 Sönke Tenckhoff , Mario Koddenbrock , Erik Rodner

Medical benchmark datasets significantly contribute to developing Large Language Models (LLMs) for medical knowledge extraction, diagnosis, summarization, and other uses. Yet, current benchmarks are mainly derived from exam questions given…

计算与语言 · 计算机科学 2025-03-11 Oriel Perets , Ofir Ben Shoham , Nir Grinberg , Nadav Rappoport

Europe's healthcare systems require enhanced interoperability and digitalization, driving a demand for innovative solutions to process legacy clinical data. This paper presents the results of our project, which aims to leverage Large…

计算与语言 · 计算机科学 2025-07-09 Aynur Guluzade , Naguib Heiba , Zeyd Boukhers , Florim Hamiti , Jahid Hasan Polash , Yehya Mohamad , Carlos A Velasco

Across medical specialties, clinical practice is anchored in evidence-based guidelines that codify best studied diagnostic and treatment pathways. These pathways routinely fall short for the long tail of real-world care not covered by…

Background: Recent advancements in large language models (LLMs) offer potential benefits in healthcare, particularly in processing extensive patient records. However, existing benchmarks do not fully assess LLMs' capability in handling…

Backgrounds: Information extraction (IE) is critical in clinical natural language processing (NLP). While large language models (LLMs) excel on generative tasks, their performance on extractive tasks remains debated. Methods: We…

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