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Adequate brain perfusion is required for proper brain function and life. Maintaining optimal brain perfusion to avoid secondary brain injury is one of the main concerns of neurocritical care. Cerebral autoregulation is responsible for…

定量方法 · 定量生物学 2022-02-09 J. K. Briggs , J. N. Stroh , T. D. Bennett , S. Park , D. J. Albers

Nasal breathing difficulties (NBD) are widespread and difficult to diagnose; the failure rate of their surgical corrections is high. Computational Fluid Dynamics (CFD) enables diagnosis of NBD and surgery planning, by comparing a…

流体动力学 · 物理学 2023-08-23 Eric Segalerba , Gabriele Dini Ciacci , Maurizio Quadrio , Jan O. Pralits

Spatial patterns of elevated wall shear stress and pressure due to blood flow past aortic stenosis (AS) are studied using GPU-accelerated patient-specific computational fluid dynamics. Three cases of moderate AS, one with a dilated…

流体动力学 · 物理学 2022-12-13 Hadi Zolfaghari , Mervyn Andiapen , Andreas Baumbach , Anthony Mathur , Rich R. Kerswell

The left atrium (LA) plays a pivotal role in modulating left ventricular filling, but our comprehension of its hemodynamics is significantly limited by the constraints of conventional ultrasound analysis. 4D flow magnetic resonance imaging…

The study is looking into the potential of using computational fluid dynamics (CFD) as a tool for predicting the outcome of surgery for alleviation of obstructive sleep apnea syndrome (OSAS). From pre- and post-operative computed tomography…

We study the two-dimensional (2D) shear flow of amorphous solids within variants of an elastoplastic model, paying particular attention to spatial correlations and time fluctuations of, e.g., local stresses. The model is based on the local…

软凝聚态物质 · 物理学 2014-03-27 Alexandre Nicolas , Kirsten Martens , Lydéric Bocquet , Jean-Louis Barrat

Numerous studies suggest that disturbed shear, causing endothelium dysfunction, can be related to neighboring vortex structures. With this motivation, this study presents a methodology to characterize the vortex structures. Precisely, we…

流体动力学 · 物理学 2021-10-12 Pawan Kumar Pandey , Malay Kumar Das

Intracranial aneurysms pose a significant clinical risk yet are difficult to detect, delineate and model due to limited annotated 3D data. We propose a cross-domain feature-transfer approach that leverages the latent geometric embeddings…

计算机视觉与模式识别 · 计算机科学 2025-09-04 Clément Hervé , Paul Garnier , Jonathan Viquerat , Elie Hachem

Computational fluid dynamics (CFD) can be used for evaluation of hemodynamics. However, its routine use is limited by labor-intensive manual segmentation, CFD mesh creation, and time-consuming simulation. This study aims to train a deep…

计算机视觉与模式识别 · 计算机科学 2025-02-18 Tina Yao , Endrit Pajaziti , Michael Quail , Silvia Schievano , Jennifer A Steeden , Vivek Muthurangu

Peristaltic pumping is hypothesized to drive fluid transport in several physiological systems, including cerebrospinal fluid flow through cerebral perivascular spaces (PVSs). Cerebral PVSs are unique in the context of peristaltic pumping…

流体动力学 · 物理学 2026-05-28 Shahaf Ella Salach , Ron Shnapp

It is of great interest to quantify the contributions of genetic variation to brain structure and function, which are usually measured by high-dimensional imaging data (e.g., magnetic resonance imaging). In addition to the variance, the…

应用统计 · 统计学 2020-05-05 Benjamin B. Risk , Hongtu Zhu

We recently demonstrated the reduction of the unified continuum and variational multiscale formulation to a computationally efficient fluid-structure interaction (FSI) formulation via three sound modeling assumptions pertaining to the…

医学物理 · 物理学 2022-01-12 Ingrid S. Lan , Ju Liu , Weiguang Yang , Alison L. Marsden

Turbulent flow physics regulates the aerodynamic properties of lifting surfaces, the thermodynamic efficiency of vapor power systems, and exchanges of natural and anthropogenic quantities between the atmosphere and ocean, to name just a few…

物理与社会 · 物理学 2024-02-12 Xiang I A Yang , Wen Zhang , Mahdi Abkar , William Anderson

Fontan-Associated Liver Disease (FALD) is a disorder arising from hemodynamic changes and venous congestion in the liver. This disease is prominent in patients with hypoplastic left heart syndrome (HLHS). Although HLHS patients typically…

医学物理 · 物理学 2025-11-06 Yaqi Li , Justin D. Weigand , Charles Puelz , Mette S. Olufsen , Alyssa Taylor-LaPole

Cardiovascular disease (CVD) risk prediction models are essential for identifying high-risk individuals and guiding preventive actions. However, existing models struggle with the challenges of real-world clinical practice as they…

Computational fluid dynamics (CFD) is a useful tool for prediction of turbulence in aerodynamic and biomedical applications. The choice of appropriate turbulence models is key to reaching accurate predictions. The present investigation…

流体动力学 · 物理学 2018-03-13 Fardin Khalili , Peshala P. T. Gamage , Hansen A. Mansy

Airborne pathogen transmission mechanisms play a key role in the spread of infectious diseases such as COVID-19. In this work, we propose a computational fluid dynamics (CFD) approach to model and statistically characterize airborne…

流体动力学 · 物理学 2023-11-07 Fatih Gulec , Falko Dressler , Andrew W. Eckford

The Cahn-Hilliard equation with an externally-prescribed chaotic shear flow is studied in two and three dimensions. The main goal is to compare and contrast the phase separation in two and three dimensions, using high-resolution numerical…

流体动力学 · 物理学 2014-12-23 Lennon O'Naraigh , Selma Shun , Aurore Naso

The study-to-study variability of bedload flux measurements in turbulent sediment transport borders an order of magnitude, even for idealized laboratory conditions. This uncertainty stems from physically poorly supported, empirical methods…

In the context of numerical simulations of the vascular system, local geometric uncertainties have not yet been examined in sufficient detail due to model complexity and the associated large numerical effort. Such uncertainties are related…

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