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We envision "AI scientists" as systems capable of skeptical learning and reasoning that empower biomedical research through collaborative agents that integrate AI models and biomedical tools with experimental platforms. Rather than taking…

Automated scientific discovery promises to accelerate progress across scientific domains. However, developing and evaluating an AI agent's capacity for end-to-end scientific reasoning is challenging as running real-world experiments is…

As a popular form of science communication, science stories attract readers because they combine engaging narratives with comprehensible scientific knowledge. However, crafting such stories requires substantial skill and effort, as writers…

人机交互 · 计算机科学 2025-04-30 Yu Zhang , Kexue Fu , Zhicong Lu

Hit identification is a central challenge in early drug discovery, traditionally requiring substantial experimental resources. Recent advances in artificial intelligence, particularly large language models (LLMs), have enabled virtual…

The rapid evolution of sophisticated cyberattacks has strained modern Security Operations Centers (SOC), which traditionally rely on rule-based or signature-driven detection systems. These legacy frameworks often generate high volumes of…

密码学与安全 · 计算机科学 2026-03-03 Chuanming Tang , Ling Qing , Shifeng Chen

Large language models (LLMs) and vision-language models (VLMs) have the potential to transform biological research by enabling autonomous experimentation. Yet, their application remains constrained by rigid protocol design, limited…

机器人学 · 计算机科学 2025-07-03 Yibo Qiu , Zan Huang , Zhiyu Wang , Handi Liu , Yiling Qiao , Yifeng Hu , Shu'ang Sun , Hangke Peng , Ronald X Xu , Mingzhai Sun

The exponential growth of scientific knowledge has made the automated generation of scientific hypotheses that combine novelty, feasibility, and research value a core challenge. Existing methods based on large language models fail to…

人工智能 · 计算机科学 2025-08-05 Shiyang Duan , Yuan Tian , Qi Bing , Xiaowei Shao

With recent advances in frontier multimodal large language models (MLLMs) for data understanding and visual reasoning, the role of LLMs has evolved from passive LLM-as-an-interface to proactive LLM-as-a-judge, enabling deeper integration…

图形学 · 计算机科学 2026-04-07 Jianxin Sun , David Lenz , Tom Peterka , Hongfeng Yu

Complex chemical space and limited knowledge scope with biases holds immense challenge for human scientists, yet in automated materials discovery. Existing intelligent methods relies more on numerical computation, leading to inefficient…

机器学习 · 计算机科学 2025-04-15 Zheyuan Lai , Yingming Pu

Retinopathy of prematurity (ROP) is a severe condition affecting premature infants, leading to abnormal retinal blood vessel growth, retinal detachment, and potential blindness. While semi-automated systems have been used in the past to…

Dermatological diagnosis requires integrating fine-grained visual perception with expert clinical knowledge. Although Multimodal Large Language Models (MLLMs) facilitate interactive medical image analysis, their application in dermatology…

计算机视觉与模式识别 · 计算机科学 2026-05-15 Yize Liu , Siyuan Yan , Ming Hu , Lie Ju , Xieji Li , Feilong Tang , Wei Feng , Zongyuan Ge

Artificial intelligence (AI) has been increasingly applied in scientific activities for decades; however, it is still far from an insightful and trustworthy collaborator in the scientific process. Most existing AI methods are either too…

人工智能 · 计算机科学 2022-02-08 Morad Behandish , John Maxwell , Johan de Kleer

There has been unprecedented interest in developing agents that expand the boundary of scientific discovery, primarily by optimizing quantitative objective functions specified by scientists. However, for grand challenges in science, these…

As data-driven methods, artificial intelligence (AI), and automated workflows accelerate scientific tasks, we see the rate of discovery increasingly limited by human decision-making tasks such as setting objectives, generating hypotheses,…

多智能体系统 · 计算机科学 2025-10-16 J. Gregory Pauloski , Kyle Chard , Ian T. Foster

While previous AI Scientist systems can generate novel findings, they often lack the focus to produce scientifically valuable contributions that address pressing human-defined challenges. We introduce DeepScientist, a system designed to…

计算与语言 · 计算机科学 2025-10-01 Yixuan Weng , Minjun Zhu , Qiujie Xie , Qiyao Sun , Zhen Lin , Sifan Liu , Yue Zhang

Rare diseases affect over 300 million individuals worldwide, yet timely and accurate diagnosis remains an urgent challenge. Patients often endure a prolonged diagnostic odyssey exceeding five years, marked by repeated referrals,…

计算与语言 · 计算机科学 2026-02-17 Weike Zhao , Chaoyi Wu , Yanjie Fan , Xiaoman Zhang , Pengcheng Qiu , Yuze Sun , Xiao Zhou , Yanfeng Wang , Xin Sun , Ya Zhang , Yongguo Yu , Kun Sun , Weidi Xie

Amodal completion, the task of inferring invisible object parts, faces significant challenges in maintaining semantic consistency and structural integrity. Prior progressive approaches are inherently limited by inference instability and…

计算机视觉与模式识别 · 计算机科学 2025-12-25 Hongxing Fan , Shuyu Zhao , Jiayang Ao , Lu Sheng

Skin diseases, such as skin cancer, are a significant public health issue, and early diagnosis is crucial for effective treatment. Artificial intelligence (AI) algorithms have the potential to assist in triaging benign vs malignant skin…

计算机视觉与模式识别 · 计算机科学 2025-03-25 Nusrat Munia , Abdullah-Al-Zubaer Imran

Current Autonomous Scientific Research (ASR) systems, despite leveraging large language models (LLMs) and agentic architectures, remain constrained by fixed workflows and toolsets that prevent adaptation to evolving tasks and environments.…

Embodied agents operating in complex and uncertain environments face considerable challenges. While some advanced agents handle complex manipulation tasks with proficiency, their success often hinges on extensive training data to develop…

机器人学 · 计算机科学 2024-04-19 Yichen Zhu , Zhicai Ou , Xiaofeng Mou , Jian Tang