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Many clinical studies require the follow-up of patients over time. This is challenging: apart from frequently observed drop-out, there are often also organizational and financial challenges, which can lead to reduced data collection and, in…

机器学习 · 计算机科学 2022-10-26 Fateme Nateghi Haredasht , Celine Vens

In this work, we study the estimation of treatment duration effects in observational survival data, where treatment and covariate histories evolve over time and longer observed durations are only attainable among individuals who remain…

When drawing causal inferences about the effects of multiple treatments on clustered survival outcomes using observational data, we need to address implications of the multilevel data structure, multiple treatments, censoring and unmeasured…

统计方法学 · 统计学 2022-02-18 Liangyuan Hu , Jiayi Ji , Ronald D. Ennis , Joseph W. Hogan

Off-policy, value-based reinforcement learning methods such as Q-learning are appealing because they can learn from arbitrary experience, including data collected by older policies or other agents. In practice, however, bootstrapping makes…

人工智能 · 计算机科学 2026-05-12 Armaan A. Abraham , Lucy Xiaoyang Shi , Chelsea Finn

Previous deep learning approaches for survival analysis have primarily relied on ranking losses to improve discrimination performance, which often comes at the expense of calibration performance. To address such an issue, we propose a novel…

机器学习 · 计算机科学 2024-11-22 Dongjoon Lee , Hyeryn Park , Changhee Lee

In this study, we present a novel Survival Analysis algorithm designed to efficiently handle large-scale longitudinal data. Our approach draws inspiration from Reinforcement Learning principles, particularly the Deep Q-Network paradigm,…

机器学习 · 计算机科学 2024-10-10 Mariana Vargas Vieyra , Pascal Frossard

A method for counterfactual explanation of machine learning survival models is proposed. One of the difficulties of solving the counterfactual explanation problem is that the classes of examples are implicitly defined through outcomes of a…

机器学习 · 计算机科学 2020-07-01 Maxim S. Kovalev , Lev V. Utkin

Estimating heterogeneous treatment effects in survival settings is complicated by right censoring as well as the time-varying nature of the estimand. While the conditional average treatment effect (CATE) provides a natural target, most…

统计方法学 · 统计学 2026-04-14 Yuming Sun , Jian Kang , Yi Li

Simulation studies are useful for evaluating and developing statistical methods for the analyses of complex problems. Performance of methods may be affected by multiple complexities present in real scenarios. Generating sufficiently…

We propose UCBMQ, Upper Confidence Bound Momentum Q-learning, a new algorithm for reinforcement learning in tabular and possibly stage-dependent, episodic Markov decision process. UCBMQ is based on Q-learning where we add a momentum term…

机器学习 · 统计学 2022-03-21 Pierre Menard , Omar Darwiche Domingues , Xuedong Shang , Michal Valko

Censored quantile regression has emerged as a prominent alternative to classical Cox's proportional hazards model or accelerated failure time model in both theoretical and applied statistics. While quantile regression has been extensively…

统计方法学 · 统计学 2024-08-27 Taehwa Choi , Seohyeon Park , Hunyong Cho , Sangbum Choi

Estimating counterfactual outcomes over time from observational data is relevant for many applications (e.g., personalized medicine). Yet, state-of-the-art methods build upon simple long short-term memory (LSTM) networks, thus rendering…

机器学习 · 计算机科学 2022-06-06 Valentyn Melnychuk , Dennis Frauen , Stefan Feuerriegel

The fundamental problem in treatment effect estimation from observational data is confounder identification and balancing. Most of the previous methods realized confounder balancing by treating all observed pre-treatment variables as…

统计方法学 · 统计学 2021-10-13 Anpeng Wu , Kun Kuang , Junkun Yuan , Bo Li , Runze Wu , Qiang Zhu , Yueting Zhuang , Fei Wu

Estimating the causal effect of time-varying treatments on survival outcomes is a challenging task in many domains, particularly in medicine where treatment protocols adapt over time. While recent advances in representation learning have…

机器学习 · 统计学 2025-05-06 Ayoub Abraich

Counterfactual inference enables clinicians to ask "what if" questions about patient outcomes, but standard methods assume feature independence and simultaneous modifiability -- assumptions violated by longitudinal clinical data. We…

机器学习 · 计算机科学 2026-02-25 Jingya Cheng , Alaleh Azhir , Jiazi Tian , Hossein Estiri

In randomized trials involving multiple treatments, bivariate survival outcomes present significant analytical challenges for making decisions. This paper addresses the problem of deriving optimal individualized treatment rules to maximize…

机器学习 · 统计学 2026-05-29 Kun Ren , Yifan Cui , Wen Su

Feature screening is an important tool in analyzing ultrahigh-dimensional data, particularly in the field of Omics and oncology studies. However, most attention has been focused on identifying features that have a linear or monotonic impact…

统计方法学 · 统计学 2023-05-10 Yaxian Chen , KF Lam , Zhonghua Liu

Individual Treatment Effects (ITE) estimation methods have risen in popularity in the last years. Most of the time, individual effects are better presented as Conditional Average Treatment Effects (CATE). Recently, representation balancing…

机器学习 · 统计学 2022-03-30 Ayoub Abraich , Agathe Guilloux , Blaise Hanczar

Counterfactual estimation over time is important in various applications, such as personalized medicine. However, time-dependent confounding bias in observational data still poses a significant challenge in achieving accurate and efficient…

机器学习 · 计算机科学 2026-03-13 Nghia D. Nguyen , Pablo Robles-Granda , Lav R. Varshney

Understanding the effects of quarantine policies in populations with underlying social networks is crucial for public health, yet most causal inference methods fail here due to their assumption of independent individuals. We introduce…

人工智能 · 计算机科学 2024-12-09 Suhan Guo , Furao Shen , Ni Li