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Background. Percutaneous coronary intervention(PCI) in stable coronary artery disease(CAD) is commonly triggered by abnormal myocardial perfusion imaging(MPI). However, due to the possibilities of multivessel disease and variability of…

医学物理 · 物理学 2020-06-15 Haipeng Tang , Robert R. Bober , Chen Zhao , Chaoyang Zhang , Huiqing Zhu , Zhuo He , Zhihui Xu , Weihua Zhou

Personalized electrocardiogram (ECG) generation is to simulate a patient's ECG digital twins tailored to specific conditions. It has the potential to transform traditional healthcare into a more accurate individualized paradigm, while…

机器学习 · 计算机科学 2026-02-03 Yongfan Lai , Bo Liu , Xinyan Guan , Qinghao Zhao , Hongyan Li , Shenda Hong

One possible way of making thermal processing controllable is to gather real-time information on the product's current state. Often, sensory equipment cannot capture all relevant information easily or at all. Digital Twins close this gap…

计算工程、金融与科学 · 计算机科学 2022-09-08 Maximilian Kannapinn , Minh Khang Pham , Michael Schäfer

Single-arm trials are an important study design for evaluating drug efficacy and safety without enrolling patients into a control arm. Although they do not provide the gold-standard evidence of randomized controlled trials, they are…

应用统计 · 统计学 2026-05-14 Daniele Bertolini , Franklin Fuller , Aaron M. Smith , Jonathan R. Walsh , Run Zhuang

Soft robots, made from compliant materials, exhibit complex dynamics due to their flexibility and high degrees of freedom. Controlling soft robots presents significant challenges, particularly underactuation, where the number of inputs is…

机器人学 · 计算机科学 2025-02-25 Wu-Te Yang , Pei-Chun Lin

Three-dimensional integrated circuit (3D IC) pack-aging and heterogeneous integration have emerged as central pillars of contemporary semiconductor scaling. Yet, the multi-physics coupling inherent to stacked architectures manifesting as…

硬件体系结构 · 计算机科学 2026-02-02 Gourab Datta , Sarah Safura Sharif , Yaser Mike Banad

Wireless digital twins can be leveraged to provide site-specific synthetic channel information through precise physical modeling and signal propagation simulations. This can help reduce the overhead of channel state information (CSI)…

信号处理 · 电气工程与系统科学 2026-04-21 Hao Luo , Saeed R. Khosravirad , Ahmed Alkhateeb

Electrocardiogram (ECG)-based biometric recognition has emerged as a promising solution for secure authentication and liveness detection. However, most existing methods rely on unimodal deep learning architectures that independently process…

计算机视觉与模式识别 · 计算机科学 2026-05-19 Arioua , Islameddine , Benzaoui , Amir , Zeroual , Abdelhafid , Houam , Lotfi

We propose a \textit{guided multi-fidelity Bayesian optimization} framework for data-efficient controller tuning that integrates corrected digital twin simulations with real-world measurements. The method targets closed-loop systems with…

机器人学 · 计算机科学 2025-10-21 Mahdi Nobar , Jürg Keller , Alessandro Forino , John Lygeros , Alisa Rupenyan

Background and objective: CTA is a gold standard of preoperative diagnosis of abdominal aorta and typically used for geometric-only characteristic extraction. We assume that a model describing the dynamic behavior of the contrast agent in…

A digital twin (DT) is a virtual representation of physical process, products and/or systems that requires a high-fidelity computational model for continuous update through the integration of sensor data and user input. In the context of…

Cardiovascular disease affects millions of people worldwide and its social and economic cost clearly motivates scientific research. Computer simulation can lead to a better understanding of cardiac physiology, and for pathology presents…

生物物理 · 物理学 2023-02-27 Toby Simpson

Digital twin (DT) enables smart manufacturing by leveraging real-time data, AI models, and intelligent control systems. This paper presents a state-of-the-art analysis on the emerging field of DTs in the context of milling. The critical…

系统与控制 · 电气工程与系统科学 2025-12-16 Wenyi Liu , R. Sharma , W. "Grace" Guo , J. Yi , Y. B. Guo

Patient-specific computational models of the heart are powerful tools for cardiovascular research and medicine, with demonstrated applications in treatment planning, device evaluation, and surgical decision-making. Yet constructing such…

医学物理 · 物理学 2026-04-21 Aaron L. Brown , Ju Liu , Daniel B. Ennis , Alison L. Marsden

We introduce the Digital Twin Catalog (DTC), a new large-scale photorealistic 3D object digital twin dataset. A digital twin of a 3D object is a highly detailed, virtually indistinguishable representation of a physical object, accurately…

The onset of Industry 4.0 is rapidly transforming the manufacturing world through the integration of cloud computing, machine learning (ML), artificial intelligence (AI), and universal network connectivity, resulting in performance…

计算机视觉与模式识别 · 计算机科学 2025-05-21 Ahmed Alhamadah , Muntasir Mamun , Henry Harms , Mathew Redondo , Yu-Zheng Lin , Jesus Pacheco , Soheil Salehi , Pratik Satam

Accurate coronary artery segmentation from coronary computed tomography angiography is essential for quantitative coronary analysis and clinical decision support. Nevertheless, reliable segmentation remains challenging because of small…

计算机视觉与模式识别 · 计算机科学 2025-12-16 Huan Huang , Michele Esposito , Chen Zhao

Coronary angiography is the gold standard imaging technique for studying and diagnosing coronary artery disease. However, the resulting 2D X-ray projections lose 3D information and exhibit visual ambiguities. In this work, we aim to…

计算机视觉与模式识别 · 计算机科学 2023-12-20 Yifan Wu , Rohit Jena , Mehmet Gulsun , Vivek Singh , Puneet Sharma , James C. Gee

Brain digital twins aim to provide faithful, individualized computational representations of brains as dynamical systems, enabling mechanistic understanding and supporting prediction of clinical interventions. Yet current approaches remain…

计算工程、金融与科学 · 计算机科学 2026-04-16 Alexandre Muzy

Simulation frameworks have been key enablers for the development and validation of autonomous driving systems. However, existing methods struggle to comprehensively address the autonomy-oriented requirements of balancing: (i) dynamical…

机器人学 · 计算机科学 2026-02-23 Tanmay Vilas Samak , Chinmay Vilas Samak , Bing Li , Venkat Krovi