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Pathology has played a crucial role in the diagnosis and evaluation of patient tissue samples obtained from surgeries and biopsies for many years. The advent of Whole Slide Scanners and the development of deep learning technologies have…

计算机视觉与模式识别 · 计算机科学 2024-08-07 Mieko Ochi , Daisuke Komura , Shumpei Ishikawa

Large language models (LLMs) have emerged as transformative tools in medicine, with strong capabilities in language understanding, reasoning, and structured information extraction. Radiation oncology is particularly well suited for LLM…

The growing interest in developing smart diagnostic systems to help medical experts process extensive data for treating incurable diseases has been notable. In particular, the challenge of identifying thyroid cancer (TC) has seen progress…

机器学习 · 计算机科学 2025-12-19 Yassine Habchi , Hamza Kheddar , Yassine Himeur , Mohamed Chahine Ghanem

Artificial intelligence (AI) is reshaping modern healthcare by advancing disease diagnosis, treatment decision-making, and biomedical research. Among AI technologies, large language models (LLMs) have become especially impactful, enabling…

人工智能 · 计算机科学 2025-11-18 Zhengda Wang , Daqian Shi , Jingyi Zhao , Xiaolei Diao , Xiongfeng Tang , Yanguo Qin

Clinical decision-making in radiology increasingly benefits from artificial intelligence (AI), particularly through large language models (LLMs). However, traditional retrieval-augmented generation (RAG) systems for radiology question…

There has been a growing interest in creating intelligent diagnostic systems to assist medical professionals in analyzing and processing big data for the treatment of incurable diseases. One of the key challenges in this field is detecting…

图像与视频处理 · 电气工程与系统科学 2023-08-29 Yassine Habchi , Yassine Himeur , Hamza Kheddar , Abdelkrim Boukabou , Shadi Atalla , Ammar Chouchane , Abdelmalik Ouamane , Wathiq Mansoor

Retrieval-Augmented Large Language Models (LLMs), which integrate external knowledge, have shown remarkable performance in medical domains, including clinical diagnosis. However, existing RAG methods often struggle to tailor retrieval…

计算与语言 · 计算机科学 2025-10-16 Jiawei He , Mingyi Jia , Zhihao Jia , Junwen Duan , Yan Song , Jianxin Wang

Large language models (LLMs) often generate outdated or inaccurate information based on static training datasets. Retrieval-augmented generation (RAG) mitigates this by integrating outside data sources. While previous RAG systems used…

Large language models (LLM) hold significant potential for applications in biomedicine, but they struggle with hallucinations and outdated knowledge. While retrieval-augmented generation (RAG) is generally employed to address these issues,…

计算与语言 · 计算机科学 2025-09-23 Jiwoong Sohn , Yein Park , Chanwoong Yoon , Sihyeon Park , Hyeon Hwang , Mujeen Sung , Hyunjae Kim , Jaewoo Kang

Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…

其他定量生物学 · 定量生物学 2025-12-19 Jiawei He , Boya Zhang , Hossein Rouhizadeh , Yingjian Chen , Rui Yang , Jin Lu , Xudong Chen , Nan Liu , Douglas Teodoro

Thyroid cancer is common worldwide, with a rapid increase in prevalence across North America in recent years. While most patients present with palpable nodules through physical examination, a large number of small and medium-sized nodules…

Advancements in generative Artificial Intelligence (AI) hold great promise for automating radiology workflows, yet challenges in interpretability and reliability hinder clinical adoption. This paper presents an automated radiology report…

Retrieval Augmented Generation (RAG) has emerged as a powerful application of Large Language Models (LLMs), revolutionizing information search and consumption. RAG systems combine traditional search capabilities with LLMs to generate…

信息检索 · 计算机科学 2025-06-12 Harsh Maheshwari , Srikanth Tenneti , Alwarappan Nakkiran

The vast amount of biomedical information available today presents a significant challenge for investigators seeking to digest, process, and understand these findings effectively. Large Language Models (LLMs) have emerged as powerful tools…

计算与语言 · 计算机科学 2024-07-19 Alexander R. Pelletier , Joseph Ramirez , Irsyad Adam , Simha Sankar , Yu Yan , Ding Wang , Dylan Steinecke , Wei Wang , Peipei Ping

Mental disorders represent a critical global health challenge, and social media is increasingly viewed as a vital resource for real-time digital phenotyping and intervention. To leverage this data, large language models (LLMs) have been…

计算与语言 · 计算机科学 2025-12-23 Zhuohan Ge , Darian Li , Yubo Wang , Nicole Hu , Xinyi Zhu , Haoyang Li , Xin Zhang , Mingtao Zhang , Shihao Qi , Yuming Xu , Han Shi , Chen Jason Zhang , Qing Li

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

Retrieval-Augmented Generation (RAG) lifts the factuality of Large Language Models (LLMs) by injecting external knowledge, yet it falls short on problems that demand multi-step inference; conversely, purely reasoning-oriented approaches…

Large language models (LLMs) offer a promising pre-screening tool, improving early disease detection and providing enhanced healthcare access for underprivileged communities. The early diagnosis of various diseases continues to be a…

Thyroid cancer is an increasing global health concern that requires advanced diagnostic methods. The application of AI and radiomics to thyroid cancer diagnosis is examined in this review. A review of multiple databases was conducted in…

Increasing clinical trial protocol complexity, amendments, and challenges around knowledge management create significant burden for trial teams. Structuring protocol content into standard formats has the potential to improve efficiency,…

信息检索 · 计算机科学 2026-04-20 Ramtin Babaeipour , François Charest , Madison Wright
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