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With the advent of Large Language Models (LLMs), medical artificial intelligence (AI) has experienced substantial technological progress and paradigm shifts, highlighting the potential of LLMs to streamline healthcare delivery and improve…

计算与语言 · 计算机科学 2024-12-10 Lei Liu , Xiaoyan Yang , Junchi Lei , Yue Shen , Jian Wang , Peng Wei , Zhixuan Chu , Zhan Qin , Kui Ren

Large language models (LLMs) achieve strong average performance yet remain unreliable at the instance level, with frequent hallucinations, brittle failures, and poorly calibrated confidence. We study reliability through the lens of…

人工智能 · 计算机科学 2026-01-13 Pranav Kallem

Building trustworthy clinical AI systems requires not only accurate predictions but also transparent, biologically grounded explanations. We present \texttt{DiagnoLLM}, a hybrid framework that integrates Bayesian deconvolution, eQTL-guided…

人工智能 · 计算机科学 2025-11-18 Bowen Xu , Xinyue Zeng , Jiazhen Hu , Tuo Wang , Adithya Kulkarni

Large Language Models (LLMs) are being adopted at an unprecedented rate, yet still face challenges in knowledge-intensive domains like biomedicine. Solutions such as pre-training and domain-specific fine-tuning add substantial computational…

The rapid adoption of large language models (LLMs) in customer service introduces new risks, as malicious actors can exploit them to conduct large-scale user impersonation through machine-generated text (MGT). Current MGT detection methods…

计算与语言 · 计算机科学 2025-08-27 Angela Yifei Yuan , Haoyi Li , Soyeon Caren Han , Christopher Leckie

Metadata play a crucial role in ensuring the findability, accessibility, interoperability, and reusability of datasets. This paper investigates the potential of large language models (LLMs), specifically GPT-4, to improve adherence to…

人工智能 · 计算机科学 2025-02-24 Sowmya S. Sundaram , Benjamin Solomon , Avani Khatri , Anisha Laumas , Purvesh Khatri , Mark A. Musen

Information overload is a major obstacle to scientific progress. The explosive growth in scientific literature and data has made it ever harder to discover useful insights in a large mass of information. Today scientific knowledge is…

Medical large language models (LLMs), including custom medical GPTs (MedGPTs) and open-source models, are increasingly deployed on web platforms to provide clinical guidance. However, they pose risks of hallucination, policy noncompliance,…

计算与语言 · 计算机科学 2026-05-21 Sunday Oyinlola Ogundoyin , Muhammad Ikram , Rahat Masood

Large Language Models (LLMs) have recently demonstrated remarkable performance in general tasks across various fields. However, their effectiveness within specific domains such as drug development remains challenges. To solve these…

Effective pre-training of large language models (LLMs) has been challenging due to the immense resource demands and the complexity of the technical processes involved. This paper presents a detailed technical report on YuLan-Mini, a highly…

计算与语言 · 计算机科学 2024-12-25 Yiwen Hu , Huatong Song , Jia Deng , Jiapeng Wang , Jie Chen , Kun Zhou , Yutao Zhu , Jinhao Jiang , Zican Dong , Wayne Xin Zhao , Ji-Rong Wen

Large Language Models (LLMs) like LLaMA, Mistral, and Gemma are increasingly used in decision-critical domains such as healthcare, law, and finance, yet their reliability remains uncertain. They often make overconfident errors, degrade…

计算与语言 · 计算机科学 2026-01-01 Rohit Kumar Salla , Manoj Saravanan , Shrikar Reddy Kota

Frontier large language models (LLMs), such as GPT-5, Claude 4.5, Gemini 3, Llama 4, and DeepSeek-R1, represent a transformative class of AI tools capable of revolutionizing various aspects of healthcare by generating human-like responses…

Since the release of ChatGPT and GPT-4, large language models (LLMs) and multimodal large language models (MLLMs) have attracted widespread attention for their exceptional capabilities in understanding, reasoning, and generation,…

计算与语言 · 计算机科学 2024-12-31 Hanguang Xiao , Feizhong Zhou , Xingyue Liu , Tianqi Liu , Zhipeng Li , Xin Liu , Xiaoxuan Huang

We propose PPLqa, an easy to compute, language independent, information-theoretic metric to measure the quality of responses of generative Large Language Models (LLMs) in an unsupervised way, without requiring ground truth annotations or…

计算与语言 · 计算机科学 2024-11-26 Gerald Friedland , Xin Huang , Yueying Cui , Vishaal Kapoor , Ashish Khetan , Sanjiv Das

Recently, Large Language Models (LLMs) have gained significant traction in medical domain, especially in developing a QA systems to Medical QA systems for enhancing access to healthcare in low-resourced settings. This paper compares five…

计算与语言 · 计算机科学 2026-02-17 Shefayat E Shams Adib , Ahmed Alfey Sani , Ekramul Alam Esham , Ajwad Abrar , Tareque Mohmud Chowdhury

Large language models (LLMs) show promise for supporting clinical decision-making in complex fields such as rheumatology. Our evaluation shows that smaller language models (SLMs), combined with retrieval-augmented generation (RAG), achieve…

In this paper, we champion the use of structured and semantic content representation of discourse-based scholarly communication, inspired by tools like Wikipedia infoboxes or structured Amazon product descriptions. These representations…

计算与语言 · 计算机科学 2024-01-19 Mahsa Shamsabadi , Jennifer D'Souza , Sören Auer

Large Language Models (LLMs) achieve gold-medal performance across many benchmarks, yet it remains unclear whether such success reflects genuine reasoning or pattern matching. From a cognitive science perspective, an informative test is…

计算与语言 · 计算机科学 2025-09-03 Fenghua Liu , Yulong Chen , Yixuan Liu , Zhujun Jin , Solomon Tsai , Ming Zhong

Vision-language models (VLMs) are increasingly adapted through domain-specific fine-tuning, yet it remains unclear whether this improves reasoning beyond superficial visual cues, particularly in high-stakes domains like medicine. We…

计算机视觉与模式识别 · 计算机科学 2026-04-14 Oliver McLaughlin , Daniel Shubin , Carsten Eickhoff , Ritambhara Singh , William Rudman , Michal Golovanevsky

This paper examines the reasoning capabilities of Large Language Models (LLMs) from a novel perspective, focusing on their ability to operate within formally specified, rule-governed environments. We evaluate four LLMs (Gemini 2.5 Pro and…

人工智能 · 计算机科学 2026-02-24 Maciej Świechowski , Adam Żychowski , Jacek Mańdziuk
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