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Because of its strong predictive skills, deep learning has emerged as an essential tool in many industries, including healthcare. Traditional deep learning models, on the other hand, frequently lack interpretability and omit to take…

机器学习 · 计算机科学 2024-08-07 Masoud Muhammed Hassan

Gene regulation is central to understanding cellular processes and development, potentially leading to the discovery of new treatments for diseases and personalized medicine. Inferring gene regulatory networks (GRNs) from single-cell RNA…

计算工程、金融与科学 · 计算机科学 2025-06-17 Tsz Pan Tong , Aoran Wang , George Panagopoulos , Jun Pang

Cancer has relational information residing at varying scales, modalities, and resolutions of the acquired data, such as radiology, pathology, genomics, proteomics, and clinical records. Integrating diverse data types can improve the…

机器学习 · 计算机科学 2024-07-29 Asim Waqas , Aakash Tripathi , Ravi P. Ramachandran , Paul Stewart , Ghulam Rasool

Time series classification is a relevant step supporting decision-making processes in various domains, and deep neural models have shown promising performance in this respect. Despite significant advancements in deep learning, the…

机器学习 · 计算机科学 2025-11-04 Irina Barašin , Blaž Bertalanič , Mihael Mohorčič , Carolina Fortuna

Brain tumors are a challenging problem in neuro-oncology, where early and precise diagnosis is important for successful treatment. Deep learning-based brain tumor classification methods often rely on heavy data augmentation which can limit…

机器学习 · 计算机科学 2026-04-20 Saraf Anzum Shreya , MD. Abu Ismail Siddique , Sharaf Tasnim

The growing need for accurate and efficient 3D identification of tumors, particularly in liver segmentation, has spurred considerable research into deep learning models. While many existing architectures offer strong performance, they often…

图像与视频处理 · 电气工程与系统科学 2024-12-30 Bhavesh Gyanchandani , Aditya Oza , Abhinav Roy

Interpreting complex datasets remains a major challenge for scientists, particularly due to high dimensionality and collinearity among variables. We introduce a novel application of Kolmogorov-Arnold Networks (KANs) to enhance…

机器学习 · 计算机科学 2025-12-19 Luis A. De la Fuente , Hernan A. Moreno , Laura V. Alvarez , Hoshin V. Gupta

The rapidly emerging field of deep learning-based computational pathology has demonstrated promise in developing objective prognostic models from histology whole slide images. However, most prognostic models are either based on histology or…

To address the issue of interpretability in multilayer perceptrons (MLPs), Kolmogorov-Arnold Networks (KANs) are introduced in 2024. However, optimizing KAN structures is labor-intensive, typically requiring manual intervention and…

神经与进化计算 · 计算机科学 2025-01-30 Quan Long , Bin Wang , Bing Xue , Mengjie Zhang

Parkinson's Disease (PD) diagnosis remains challenging. This study applies Convolutional Kolmogorov-Arnold Networks (ConvKANs), integrating learnable spline-based activation functions into convolutional layers, for PD classification using…

图像与视频处理 · 电气工程与系统科学 2024-09-27 Salil B Patel , Vicky Goh , James F FitzGerald , Chrystalina A Antoniades

The increasing use of machine learning in clinical decision support has been limited by the lack of transparency of many high-performing models. In clinical settings, predictions must be interpretable, auditable, and actionable. This study…

Framing the investigation of diverse cancers as a machine learning problem has recently shown significant potential in multi-omics analysis and cancer research. Empowering these successful machine learning models are the high-quality…

基因组学 · 定量生物学 2025-06-17 Ziwei Yang , Rikuto Kotoge , Xihao Piao , Zheng Chen , Lingwei Zhu , Peng Gao , Yasuko Matsubara , Yasushi Sakurai , Jimeng Sun

In traditional neural network architectures, a multilayer perceptron (MLP) is typically employed as a classification block following the feature extraction stage. However, the Kolmogorov-Arnold Network (KAN) presents a promising alternative…

计算机视觉与模式识别 · 计算机科学 2024-09-09 Valeriy Lobanov , Nikita Firsov , Evgeny Myasnikov , Roman Khabibullin , Artem Nikonorov

Multi-omics data integration is crucial for understanding complex diseases, yet limited sample sizes, noise, and heterogeneity often reduce predictive power. To address these challenges, we introduce Omics-GAN, a Generative Adversarial…

定量方法 · 定量生物学 2025-10-24 Md Selim Reza , Sabrin Afroz , Mostafizer Rahman , Md Ashad Alam

Cancer subtype classification is crucial for personalized treatment and prognostic assessment. However, effectively integrating multi-omic data remains challenging due to the heterogeneous nature of genomic, epigenomic, and transcriptomic…

机器学习 · 计算机科学 2025-06-10 Sajib Acharjee Dip , Uddip Acharjee Shuvo , Dipanwita Mallick , Abrar Rahman Abir , Liqing Zhang

Skin cancer classification is a crucial task in medical image analysis, where precise differentiation between malignant and non-malignant lesions is essential for early diagnosis and treatment. In this study, we explore Sequential and…

计算机视觉与模式识别 · 计算机科学 2025-08-19 Shubhi Agarwal , Amulya Kumar Mahto

High-dimensional linear mappings, or linear layers, dominate both the parameter count and the computational cost of most modern deep-learning models. We introduce a general-purpose drop-in replacement, lookup multivariate Kolmogorov-Arnold…

机器学习 · 计算机科学 2025-10-20 Sergey Pozdnyakov , Philippe Schwaller

Accurate segmentation of individual teeth from panoramic radiographs remains a challenging task due to anatomical variations, irregular tooth shapes, and overlapping structures. These complexities often limit the performance of conventional…

计算机视觉与模式识别 · 计算机科学 2025-12-05 Md Mizanur Rahman Mustakim , Jianwu Li , Sumya Bhuiyan , Mohammad Mehedi Hasan , Bing Han

We firstly simulated disease dynamics by KAN (Kolmogorov-Arnold Networks) nearly 4 years ago, but the kernel functions in the edge include the exponential number of infected and discharged people and is also in line with the…

神经与进化计算 · 计算机科学 2024-06-04 Jun-Bo Tao , Bai-Qing Sun , Wei-Dong Zhu , Shi-You Qu , Jia-Qiang Li , Guo-Qi Li , Yan-Yan Wang , Ling-Kun Chen , Chong Wu , Yu Xiong , Jiaxuan Zhou

Genomics, especially multi-omics, has made precision medicine feasible. The completion and publicly accessible multi-omics resource with clinical outcome, such as The Cancer Genome Atlas (TCGA) is a great test bed for developing…

基因组学 · 定量生物学 2020-08-31 Lana X Garmire