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Quantifying the evolution and complexity of materials is of importance in many areas of science and engineering, where a central open challenge is developing experimental complexity measurements to distinguish random structures from evolved…

材料科学 · 物理学 2025-02-26 Keith Y Patarroyo , Abhishek Sharma , Ian Seet , Ignas Packmore , Sara I. Walker , Leroy Cronin

Complexity and heterogeneity of bone tissue require a multiscale modelling to understand their mechanical behaviour and their remodelling mechanism. Human cortical bone structure consists of six structural scale levels which are the…

医学物理 · 物理学 2011-12-07 Abdelwahed Barkaoui , Ridha Hambli

The complexity and heterogeneity of bone tissue require a multiscale modelling to understand its mechanical behaviour and its remodelling mechanisms. In this paper, a novel multiscale hierarchical approach including microfibril scale based…

医学物理 · 物理学 2014-03-13 Abdelwahed Barkaoui , Abdessalem Chamekh , Merzouki Tarek , Ridha Hambli , Mkaddem Ali

Mineralized collagen microfibrils in human bone provide its mechanical properties (stiffness, elasticity, ductility, energy dissipation and strength). However, detailed 3D finite element models describing the mechanical behaviour of the…

组织与器官 · 定量生物学 2012-03-01 Ridha Hambli , Abdelwahed Barkaoui

Distinguishing agents of bone modification at paleoanthropological sites is at the root of much of the research directed at understanding early hominin exploitation of large animal resources and the effects those subsistence behaviors had…

计算机视觉与模式识别 · 计算机科学 2022-05-25 Katrina Yezzi-Woodley , Alexander Terwilliger , Jiafeng Li , Eric Chen , Martha Tappen , Jeff Calder , Peter J. Olver

Molecular-level understanding of the interactions between the constituents of an atomic structure is essential for designing novel materials in various applications. This need goes beyond the basic knowledge of the number and types of…

Natural hard composites like human bone possess a combination of strength and toughness that exceeds that of their constituents and of many engineered composites. This augmentation is attributed to their complex hierarchical structure,…

Transmission electron microscopy (TEM) is a potent technique for the determination of three-dimensional atomic scale structure of samples in structural biology and materials science. In structural biology, three-dimensional structures of…

Atom probe tomography (APT) analysis conditions play a major role in the composition measurement accuracy. Preferential evaporation, which significantly biases apparent composition, more than other well-known phenomena in APT, is strongly…

Understanding the structures of biological macromolecules is highly important as they are closely associated with cellular functionalities. Comprehending the precise organization actin filaments is crucial because they form the dynamic…

图像与视频处理 · 电气工程与系统科学 2024-03-27 Salim Sazzed

Porous microstructures, while central to many functional materials, remain difficult to characterize quantitatively by atom probe tomography (APT). Although several strategies have been proposed over the past decade, most remain constrained…

Atom probe tomography (APT) is a valuable near-atomic scale imaging technique, which yields mass spectrographic data. Experimental correctness can often pivot on the identification of peaks within a dataset, this is a manual process where…

原子物理 · 物理学 2017-11-21 Daniel Haley , Pyuck-Pa Choi , Dierk Raabe

The mineralized collagen fibril is the main building block of hard tissues and it directly affects the macroscopic mechanics of biological tissues such as bone. The mechanical behavior of the fibril itself is determined by its structure:…

组织与器官 · 定量生物学 2024-03-19 Julia Kamml , Claire Acevedo , David Kammer

Determining atomic structure from spectroscopic data is central to materials science but remains restricted to a limited set of techniques and material classes, largely due to the computational cost and complexity of structural refinement.…

材料科学 · 物理学 2026-02-25 Ian Slagle , Faisal Alamgir , Victor Fung

Understanding the structure and chemical composition at the liquid-nanoparticle (NP) interface is crucial for a wide range of physical, chemical and biological processes. In this study, direct imaging of the liquid-NP interface by atom…

Three-dimensional reconstruction of atomic structure, known as atomic electron tomography (AET), has found increasing applications in materials science. The AET has been limited to very small nanoparticles due to the challenges of obtaining…

材料科学 · 物理学 2024-01-24 Liangze Mao , Jizhe Cui , Rong Yu

Photoemission orbital tomography (POT) is a powerful tool for investigating the orbitals and electronic band structure of oriented layers of organic molecules. In many cases, POT allows conclusions to be drawn regarding the geometric…

Functional properties of nanomaterials strongly depend on their surface atomic structure, but they often become largely different from their bulk structure, exhibiting surface reconstructions and relaxations. However, most of the surface…

材料科学 · 物理学 2021-10-01 Juhyeok Lee , Chaehwa Jeong , Yongsoo Yang

The mechanical properties of collagen fibrils depend on the amount and the distribution of water molecules within the fibrils. Here, we use atomic force microscopy (AFM) to study the effect of hydration on the viscoelastic properties of…

软凝聚态物质 · 物理学 2019-10-03 Manuel R. Uhlig , Robert Magerle

Protein quantification and analysis are well-accepted approaches for biomarker discovery but are limited to identification without structural information. High-throughput omics data (i.e., genomics, transcriptomics, and proteomics) have…