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Natural Language Processing (NLP) is witnessing a remarkable breakthrough driven by the success of Large Language Models (LLMs). LLMs have gained significant attention across academia and industry for their versatile applications in text…

计算与语言 · 计算机科学 2024-04-16 Taojun Hu , Xiao-Hua Zhou

Large Language Models (LLMs) have revolutionized the field of natural language processing, but they fall short in comprehending biological sequences such as proteins. To address this challenge, we propose InstructProtein, an innovative LLM…

生物大分子 · 定量生物学 2023-10-06 Zeyuan Wang , Qiang Zhang , Keyan Ding , Ming Qin , Xiang Zhuang , Xiaotong Li , Huajun Chen

The emergence of pre-trained language models (PLMs) has shown great success in many Natural Language Processing (NLP) tasks including text classification. Due to the minimal to no feature engineering required when using these models, PLMs…

计算与语言 · 计算机科学 2022-11-07 Yasmen Wahba , Nazim Madhavji , John Steinbacher

Unlocking the next generation of biotechnology and therapeutic innovation demands overcoming the inherent complexity and resource-intensity of conventional protein engineering methods. Recent GenAI-powered computational techniques often…

Natural Language Processing (NLP) systems often make use of machine learning techniques that are unfamiliar to end-users who are interested in analyzing clinical records. Although NLP has been widely used in extracting information from…

人机交互 · 计算机科学 2017-07-10 Gaurav Trivedi , Phuong Pham , Wendy Chapman , Rebecca Hwa , Janyce Wiebe , Harry Hochheiser

This paper introduces diffusion protein language model (DPLM), a versatile protein language model that demonstrates strong generative and predictive capabilities for protein sequences. We first pre-train scalable DPLMs from…

机器学习 · 计算机科学 2024-10-17 Xinyou Wang , Zaixiang Zheng , Fei Ye , Dongyu Xue , Shujian Huang , Quanquan Gu

With a focus on natural language processing (NLP) and the role of large language models (LLMs), we explore the intersection of machine learning, deep learning, and artificial intelligence. As artificial intelligence continues to…

Protein engineering is an emerging field in biotechnology that has the potential to revolutionize various areas, such as antibody design, drug discovery, food security, ecology, and more. However, the mutational space involved is too vast…

生物大分子 · 定量生物学 2023-07-28 Yuchi Qiu , Guo-Wei Wei

In this paper, we introduce HugNLP, a unified and comprehensive library for natural language processing (NLP) with the prevalent backend of HuggingFace Transformers, which is designed for NLP researchers to easily utilize off-the-shelf…

计算与语言 · 计算机科学 2023-03-01 Jianing Wang , Nuo Chen , Qiushi Sun , Wenkang Huang , Chengyu Wang , Ming Gao

The number and dynamic nature of web and mobile applications presents significant challenges for assessing their compliance with data protection laws. In this context, symbolic and statistical Natural Language Processing (NLP) techniques…

计算与语言 · 计算机科学 2025-12-22 David Rodriguez , Ian Yang , Jose M. Del Alamo , Norman Sadeh

Large language models (LLMs) have revolutionized Natural Language Processing (NLP) by minimizing the need for complex feature engineering. However, the application of LLMs in specialized domains like biopharmaceuticals and chemistry remains…

Large language models (LLMs) trained on text demonstrated remarkable results on natural language processing (NLP) tasks. These models have been adapted to decipher the language of DNA, where sequences of nucleotides act as "words" that…

Designing de novo proteins beyond those found in nature holds significant promise for advancements in both scientific and engineering applications. Current methodologies for protein design often rely on AI-based models, such as surrogate…

软凝聚态物质 · 物理学 2024-02-08 A. Ghafarollahi , M. J. Buehler

Natural language processing (NLP) has been traditionally applied to medicine, and generative large language models (LLMs) have become prominent recently. However, the differences between them across different medical tasks remain…

With the exponential increase in online scientific literature, identifying reliable domain-specific data has become increasingly important but also very challenging. Manual data collection and filtering for domain-specific scientific…

信息检索 · 计算机科学 2026-03-10 Nikita Gautam , Doina Caragea , Ignacio Ciampitti , Federico Gomez

This research investigates the application of Large Language Models (LLMs) to augment conversational agents in process mining, aiming to tackle its inherent complexity and diverse skill requirements. While LLM advancements present novel…

人工智能 · 计算机科学 2023-07-20 Urszula Jessen , Michal Sroka , Dirk Fahland

With advances in foundational and vision-language models, and effective fine-tuning techniques, a large number of both general and special-purpose models have been developed for a variety of visual tasks. Despite the flexibility and…

计算机视觉与模式识别 · 计算机科学 2024-12-25 Wan-Cyuan Fan , Tanzila Rahman , Leonid Sigal

This paper demonstrates that language models are strong structure-based protein designers. We present LM-Design, a generic approach to reprogramming sequence-based protein language models (pLMs), that have learned massive sequential…

机器学习 · 计算机科学 2023-02-10 Zaixiang Zheng , Yifan Deng , Dongyu Xue , Yi Zhou , Fei YE , Quanquan Gu

Autonomous tuning of particle accelerators is an active and challenging field of research with the goal of enabling novel accelerator technologies cutting-edge high-impact applications, such as physics discovery, cancer research and…

计算与语言 · 计算机科学 2024-05-16 Jan Kaiser , Annika Eichler , Anne Lauscher

Significant advancements have been made in one of the most critical branches of artificial intelligence: natural language processing (NLP). These advancements are exemplified by the remarkable success of OpenAI's GPT-3.5/4 and the recent…

材料科学 · 物理学 2025-04-22 Zongrui Pei , Junqi Yin , Jiaxin Zhang