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Clinical trial matching is a key process in health delivery and discovery. In practice, it is plagued by overwhelming unstructured data and unscalable manual processing. In this paper, we conduct a systematic study on scaling clinical trial…

Large language models (LLMs) are increasingly used to extract structured information from free-text clinical records, but prior work often focuses on single tasks, limited models, and English-language reports. We evaluated 15 open-weight…

Large language models (LLMs) have shown remarkable progress in coding and math problem-solving, but evaluation on advanced research-level problems in hard sciences remains scarce. To fill this gap, we present CMT-Benchmark, a dataset of 50…

Large language models have exhibited exceptional performance on various Natural Language Processing (NLP) tasks, leveraging techniques such as the pre-training, and instruction fine-tuning. Despite these advances, their effectiveness in…

计算与语言 · 计算机科学 2023-06-19 Guangyu Wang , Guoxing Yang , Zongxin Du , Longjun Fan , Xiaohu Li

Recent advances in large language models (LLMs) have shown impressive ability in biomedical question-answering, but have not been adequately investigated for more specific biomedical applications. This study investigates the performance of…

计算与语言 · 计算机科学 2024-03-29 Shan Chen , Yingya Li , Sheng Lu , Hoang Van , Hugo JWL Aerts , Guergana K. Savova , Danielle S. Bitterman

There is increasing interest in the application large language models (LLMs) to the medical field, in part because of their impressive performance on medical exam questions. While promising, exam questions do not reflect the complexity of…

Large Language Models (LLMs) such as ChatGPT demonstrate significant potential in the medical domain and are often evaluated using multiple-choice questions (MCQs) modeled on exams like the USMLE. However, such benchmarks may overestimate…

计算与语言 · 计算机科学 2025-08-22 Maxime Griot , Jean Vanderdonckt , Demet Yuksel , Coralie Hemptinne

In recent years, large language models (LLMs) have demonstrated remarkable potential across various medical applications. Building on this foundation, multimodal large language models (MLLMs) integrate LLMs with visual models to process…

计算与语言 · 计算机科学 2025-03-11 Xiaoyi Liang , Mouxiao Bian , Moxin Chen , Lihao Liu , Junjun He , Jie Xu , Lin Li

Evaluating large language models (LLMs) for medical applications remains challenging due to benchmark saturation, limited data accessibility, and insufficient coverage of relevant tasks. Existing suites have either saturated, heavily depend…

Large language models (LLMs) are increasingly used in healthcare, yet standardised benchmarks for evaluating guideline-based clinical reasoning are missing. This study introduces a validated dataset derived from publicly available…

计算与语言 · 计算机科学 2025-11-04 Qing Ding , Eric Hua Qing Zhang , Felix Jozsa , Julia Ive

Patient experience and care quality are crucial for a hospital's sustainability and reputation. The analysis of patient feedback offers valuable insight into patient satisfaction and outcomes. However, the unstructured nature of these…

计算与语言 · 计算机科学 2025-02-21 Hajar Sakai , Sarah S. Lam , Mohammadsadegh Mikaeili , Joshua Bosire , Franziska Jovin

The widespread adoption of large language models (LLMs) in healthcare raises critical questions about their ability to interpret patient-generated narratives, which are often informal, ambiguous, and noisy. Existing benchmarks typically…

计算与语言 · 计算机科学 2025-09-16 Eden Mama , Liel Sheri , Yehudit Aperstein , Alexander Apartsin

Large language models (LLMs) have achieved expert-level performance on standardized examinations, yet multiple-choice accuracy poorly reflects real-world clinical utility and safety. As patients and clinicians increasingly use LLMs for…

Brief hospital course (BHC) summaries are clinical documents that summarize a patient's hospital stay. While large language models (LLMs) depict remarkable capabilities in automating real-world tasks, their capabilities for healthcare…

Rare diseases affect hundreds of millions worldwide, yet diagnosis often spans years. Convectional pipelines decouple noisy evidence extraction from downstream inferential diagnosis, and general/medical large language models (LLMs) face…

With the rapid development of artificial intelligence (AI), large language models (LLMs) have shown strong capabilities in natural language understanding, reasoning, and generation, attracting amounts of research interest in applying LLMs…

人工智能 · 计算机科学 2024-07-30 Tongyue Shi , Jun Ma , Zihan Yu , Haowei Xu , Minqi Xiong , Meirong Xiao , Yilin Li , Huiying Zhao , Guilan Kong

Large language models (LLMs) such as GPT-4o and o1 have demonstrated strong performance on clinical natural language processing (NLP) tasks across multiple medical benchmarks. Nonetheless, two high-impact NLP tasks - structured tabular…

We present Clinical Camel, an open large language model (LLM) explicitly tailored for clinical research. Fine-tuned from LLaMA-2 using QLoRA, Clinical Camel achieves state-of-the-art performance across medical benchmarks among openly…

计算与语言 · 计算机科学 2023-08-21 Augustin Toma , Patrick R. Lawler , Jimmy Ba , Rahul G. Krishnan , Barry B. Rubin , Bo Wang

Millions of clinicians use ChatGPT to support clinical care, but evaluations of the most common use cases in model-clinician conversations are limited. We introduce HealthBench Professional, an open benchmark for evaluating large language…

Recently, Large Language Models (LLM) have demonstrated impressive capability to solve a wide range of tasks. However, despite their success across various tasks, no prior work has investigated their capability in the biomedical domain yet.…

计算与语言 · 计算机科学 2024-02-21 Israt Jahan , Md Tahmid Rahman Laskar , Chun Peng , Jimmy Huang