中文
相关论文

相关论文: Can Large Language Models Predict Antimicrobial Re…

200 篇论文

Purpose: Large Language Models (LLMs) like GPT (Generative Pre-trained Transformer) from OpenAI and LLaMA (Large Language Model Meta AI) from Meta AI are increasingly recognized for their potential in the field of cheminformatics,…

生物大分子 · 定量生物学 2024-05-22 Shaghayegh Sadeghi , Alan Bui , Ali Forooghi , Jianguo Lu , Alioune Ngom

Software developers frequently hard-code credentials such as passwords, generic secrets, private keys, and generic tokens in software repositories, even though it is strictly advised against due to the severe threat to the security of the…

密码学与安全 · 计算机科学 2025-06-17 Chidera Biringa , Gokhan Kul

Pre-trained large language models(LLMs) have attracted increasing attention in biomedical domains due to their success in natural language processing. However, the complex traits and heterogeneity of multi-sources genomics data pose…

This paper pursues the insight that large language models (LLMs) trained to generate code can vastly improve the effectiveness of mutation operators applied to programs in genetic programming (GP). Because such LLMs benefit from training…

神经与进化计算 · 计算机科学 2022-06-20 Joel Lehman , Jonathan Gordon , Shawn Jain , Kamal Ndousse , Cathy Yeh , Kenneth O. Stanley

Continual learning requires a model to adapt to ongoing changes in the data distribution, and often to the set of tasks to be performed. It is rare, however, that the data and task changes are completely unpredictable. Given a description…

计算机视觉与模式识别 · 计算机科学 2024-03-13 Mark D. McDonnell , Dong Gong , Ehsan Abbasnejad , Anton van den Hengel

Large Language Models (LLMs) have demonstrated remarkable zero-shot generalization across various language-related tasks, including search engines. However, existing work utilizes the generative ability of LLMs for Information Retrieval…

计算与语言 · 计算机科学 2024-12-31 Weiwei Sun , Lingyong Yan , Xinyu Ma , Shuaiqiang Wang , Pengjie Ren , Zhumin Chen , Dawei Yin , Zhaochun Ren

The classification of genetic variants, particularly Variants of Uncertain Significance (VUS), poses a significant challenge in clinical genetics and precision medicine. Large Language Models (LLMs) have emerged as transformative tools in…

Large Language Models (LLMs), typified by OpenAI's GPT, have marked a significant advancement in artificial intelligence. Trained on vast amounts of text data, LLMs are capable of understanding and generating human-like text across a…

人工智能 · 计算机科学 2024-10-29 Haochen Zhang , Yuyang Dong , Chuan Xiao , Masafumi Oyamada

The integration of Large Language Models (LLMs) into the drug discovery and development field marks a significant paradigm shift, offering novel methodologies for understanding disease mechanisms, facilitating drug discovery, and optimizing…

定量方法 · 定量生物学 2024-09-10 Yizhen Zheng , Huan Yee Koh , Maddie Yang , Li Li , Lauren T. May , Geoffrey I. Webb , Shirui Pan , George Church

Adversarial attacks pose significant challenges to deep neural networks (DNNs) such as Transformer models in natural language processing (NLP). This paper introduces a novel defense strategy, called GenFighter, which enhances adversarial…

机器学习 · 计算机科学 2024-04-18 Md Athikul Islam , Edoardo Serra , Sushil Jajodia

Prevalent solution for BioNER involves using representation learning techniques coupled with sequence labeling. However, such methods are inherently task-specific, demonstrate poor generalizability, and often require dedicated model for…

计算与语言 · 计算机科学 2024-04-30 Junyi Biana , Weiqi Zhai , Xiaodi Huang , Jiaxuan Zheng , Shanfeng Zhu

Generative classifiers offer potential advantages over their discriminative counterparts, namely in the areas of data efficiency, robustness to data shift and adversarial examples, and zero-shot learning (Ng and Jordan,2002; Yogatama et…

计算与语言 · 计算机科学 2019-10-02 Xiaoan Ding , Kevin Gimpel

Machine learning (ML) holds great promise for clinical applications but is often hindered by limited access to high-quality data due to privacy concerns, high costs, and long timelines associated with clinical trials. While large language…

计算与语言 · 计算机科学 2026-03-27 Zerui Xu , Fang Wu , Yingzhou Lu , Yuanyuan Zhang , Yue Zhao

This paper explores the utility of a Large Language Model (LLM) to automatically generate queries and query variants from a description of an information need. Given a set of information needs described as backstories, we explore how…

信息检索 · 计算机科学 2025-01-31 Marwah Alaofi , Luke Gallagher , Mark Sanderson , Falk Scholer , Paul Thomas

Models based on machine learning can enable accurate and fast molecular property predictions, which is of interest in drug discovery and material design. Various supervised machine learning models have demonstrated promising performance,…

机器学习 · 计算机科学 2022-12-15 Jerret Ross , Brian Belgodere , Vijil Chenthamarakshan , Inkit Padhi , Youssef Mroueh , Payel Das

Generative seq2seq dialogue systems are trained to predict the next word in dialogues that have already occurred. They can learn from large unlabeled conversation datasets, build a deeper understanding of conversational context, and…

计算与语言 · 计算机科学 2019-11-21 Sam Shleifer , Manish Chablani , Anitha Kannan , Namit Katariya , Xavier Amatriain

Large Language Models (LLMs) have demonstrated remarkable multilingual capabilities, making them promising tools in both high- and low-resource languages. One particularly valuable use case is generating synthetic samples that can be used…

计算与语言 · 计算机科学 2026-01-26 Branislav Pecher , Jan Cegin , Robert Belanec , Ivan Srba , Jakub Simko , Maria Bielikova

Algorithms that use Large Language Models (LLMs) to evolve code arrived on the Genetic Programming (GP) scene very recently. We present LLM GP, a formalized LLM-based evolutionary algorithm designed to evolve code. Like GP, it uses…

神经与进化计算 · 计算机科学 2024-01-17 Erik Hemberg , Stephen Moskal , Una-May O'Reilly

Unsupervised learning of generative models has seen tremendous progress over recent years, in particular due to generative adversarial networks (GANs), variational autoencoders, and flow-based models. GANs have dramatically improved sample…

计算机视觉与模式识别 · 计算机科学 2020-01-06 Thomas Lucas , Konstantin Shmelkov , Karteek Alahari , Cordelia Schmid , Jakob Verbeek

Large Language Models have demonstrated remarkable abilities in reasoning and planning by breaking down complex problems into sequential steps. Despite their success in various domains like mathematical problem-solving and coding, LLMs face…

人工智能 · 计算机科学 2024-10-29 Chang Ma , Haiteng Zhao , Junlei Zhang , Junxian He , Lingpeng Kong