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Multi-modal biological, imaging, and neuropsychological markers have demonstrated promising performance for distinguishing Alzheimer's disease (AD) patients from cognitively normal elders. However, it remains difficult to early predict when…

计算机视觉与模式识别 · 计算机科学 2019-01-08 Hongming Li , Yong Fan

Dementia is a neurological syndrome marked by cognitive decline. Alzheimer's disease (AD) and Frontotemporal dementia (FTD) are the common forms of dementia, each with distinct progression patterns. EEG, a non-invasive tool for recording…

信号处理 · 电气工程与系统科学 2024-08-21 Shivani Ranjan , Ayush Tripathi , Harshal Shende , Robin Badal , Amit Kumar , Pramod Yadav , Deepak Joshi , Lalan Kumar

Alzheimer's Disease (AD) is a severe brain disorder, destroying memories and brain functions. AD causes chronically, progressively, and irreversibly cognitive declination and brain damages. The reliable and effective evaluation of early…

图像与视频处理 · 电气工程与系统科学 2021-01-07 Kuo Yang , Emad A. Mohammed

Dementia is a neurodegenerative disorder that causes cognitive decline and affects more than 50 million people worldwide. Dementia is under-diagnosed by healthcare professionals - only one in four people who suffer from dementia are…

Alzheimer's disease (AD), the predominant form of dementia, is a growing global challenge, emphasizing the urgent need for accurate and early diagnosis. Current clinical diagnoses rely on radiologist expert interpretation, which is prone to…

图像与视频处理 · 电气工程与系统科学 2024-07-12 Simisola Odimayo , Chollette C. Olisah , Khadija Mohammed

Our interaction with others largely hinges on how we semantically organize the social world. The organization of such conceptual information is not static -- as we age, our experiences and ever-changing anatomy alter how we represent and…

神经元与认知 · 定量生物学 2024-04-24 Y. Ivette Colón , Matthew Rouse , Matthew A. Lambon Ralph , Timothy T. Rogers

Dementia is associated with language disorders which impede communication. Here, we automatically learn linguistic disorder patterns by making use of a moderately-sized pre-trained language model and forcing it to focus on reformulated…

计算与语言 · 计算机科学 2023-10-17 Dimitris Gkoumas , Matthew Purver , Maria Liakata

Deep learning (DL) techniques involving fine-tuning large numbers of model parameters have delivered impressive performance on the task of discriminating between language produced by cognitively healthy individuals, and those with…

计算与语言 · 计算机科学 2022-03-28 Changye Li , David Knopman , Weizhe Xu , Trevor Cohen , Serguei Pakhomov

Understanding deep neural network (DNN) behavior requires more than evaluating classification accuracy alone; analyzing errors and their predictability is equally crucial. Current evaluation methodologies lack transparency, particularly in…

计算机视觉与模式识别 · 计算机科学 2026-01-29 Katarzyna Filus , Michał Romaszewski , Mateusz Żarski

Alzheimers Disease AD is an acute neuro disease that degenerates the brain cells and thus leads to memory loss progressively. It is a fatal brain disease that mostly affects the elderly. It steers the decline of cognitive and biological…

机器学习 · 计算机科学 2023-04-20 Nair Bini Balakrishnan , P. S. Sreeja , Jisha Jose Panackal

It takes several years for the developing brain of a baby to fully master word repetition-the task of hearing a word and repeating it aloud. Repeating a new word, such as from a new language, can be a challenging task also for adults.…

计算与语言 · 计算机科学 2025-06-17 Daniel Dager , Robin Sobczyk , Emmanuel Chemla , Yair Lakretz

This paper develops a novel methodology for using symbolic knowledge in deep learning. From first principles, we derive a semantic loss function that bridges between neural output vectors and logical constraints. This loss function captures…

人工智能 · 计算机科学 2018-06-11 Jingyi Xu , Zilu Zhang , Tal Friedman , Yitao Liang , Guy Van den Broeck

Linguistic anomalies detectable in spontaneous speech have shown promise for various clinical applications including screening for dementia and other forms of cognitive impairment. The feasibility of deploying automated tools that can…

音频与语音处理 · 电气工程与系统科学 2022-11-15 Changye Li , Trevor Cohen , Serguei Pakhomov

Objective Alzheimer disease (AD) is the most common cause of dementia, a syndrome characterized by cognitive impairment severe enough to interfere with activities of daily life. We aimed to conduct a systematic literature review (SLR) of…

定量方法 · 定量生物学 2021-08-31 Sayantan Kumar , Inez Oh , Suzanne Schindler , Albert M Lai , Philip R O Payne , Aditi Gupta

Dementia, a prevalent neurodegenerative condition, is a major manifestation of Alzheimer's disease (AD). As the condition progresses from mild to severe, it significantly impairs the individual's ability to perform daily tasks…

机器学习 · 计算机科学 2023-11-06 Md Gulzar Hussain , Ye Shiren

Dementia is a group of irreversible, chronic, and progressive neurodegenerative disorders resulting in impaired memory, communication, and thought processes. In recent years, clinical research advances in brain aging have focused on the…

Recurrent neural networks (RNNs) notoriously struggle to learn long-term memories, primarily due to vanishing and exploding gradients. The recent success of state-space models (SSMs), a subclass of RNNs, to overcome such difficulties…

机器学习 · 计算机科学 2024-11-06 Nicolas Zucchet , Antonio Orvieto

The most frequent kind of dementia of the nervous system, Alzheimer's disease, weakens several brain processes (such as memory) and eventually results in death. The clinical study uses magnetic resonance imaging to diagnose AD. Deep…

图像与视频处理 · 电气工程与系统科学 2023-10-30 Sarasadat Foroughipoor , Kimia Moradi , Hamidreza Bolhasani

We propose a mesh-based technique to aid in the classification of Alzheimer's disease dementia (ADD) using mesh representations of the cortex and subcortical structures. Deep learning methods for classification tasks that utilize structural…

图像与视频处理 · 电气工程与系统科学 2022-03-14 Emanuel A. Azcona , Pierre Besson , Yunan Wu , Arjun Punjabi , Adam Martersteck , Amil Dravid , Todd B. Parrish , S. Kathleen Bandt , Aggelos K. Katsaggelos

Deep learning models suffer from the problem of semantic discontinuity: small perturbations in the input space tend to cause semantic-level interference to the model output. We argue that the semantic discontinuity results from these…

机器学习 · 计算机科学 2024-06-18 Shangxi Wu , Dongyuan Lu , Xian Zhao , Lizhang Chen , Jitao Sang
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