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Spatial transcriptomics data analysis integrates cellular transcriptional activity with spatial coordinates to identify spatial domains, infer cell-type dynamics, and characterize gene expression patterns within tissues. Despite recent…

定量方法 · 定量生物学 2026-03-25 Sean Cottrell , Guo-Wei Wei , Longxiu Huang

Dual-energy computed tomography (DECT) enables material-specific imaging through acquisitions at two different X-ray energy spectra. Material decomposition from DECT data is an ill-posed inverse problem that is highly sensitive to noise…

The rapid development of spatial transcriptomics (ST) offers new opportunities to explore the gene expression patterns within the spatial microenvironment. Current research integrates pathological images to infer gene expression, addressing…

Deep learning methods, including Convolutional Neural Networks, Transformers and Mamba, have achieved remarkable success in hyperspectral image (HSI) classification. Nevertheless, existing methods exhibit inflexible integration of…

计算机视觉与模式识别 · 计算机科学 2026-03-26 Jiawen Wen , Suixuan Qiu , Zihang Luo , Xiaofei Yang , Haotian Shi

Fine-tuning pre-trained Vision Transformers (ViTs) has showcased significant promise in enhancing visual recognition tasks. Yet, the demand for individualized and comprehensive fine-tuning processes for each task entails substantial…

计算机视觉与模式识别 · 计算机科学 2024-05-16 Weifeng Lin , Ziheng Wu , Wentao Yang , Mingxin Huang , Jun Huang , Lianwen Jin

Spatial transcriptomics is a technology that captures gene expression levels at different spatial locations, widely used in tumor microenvironment analysis and molecular profiling of histopathology, providing valuable insights into…

计算机视觉与模式识别 · 计算机科学 2025-06-11 Junzhuo Liu , Markus Eckstein , Zhixiang Wang , Friedrich Feuerhake , Dorit Merhof

Hyperspectral imaging provides precise classification for land use and cover due to its exceptional spectral resolution. However, the challenges of high dimensionality and limited spatial resolution hinder its effectiveness. This study…

计算机视觉与模式识别 · 计算机科学 2024-03-05 Shivam Pande

Unsupervised domain adaptation techniques, extensively studied in hyperspectral image (HSI) classification, aim to use labeled source domain data and unlabeled target domain data to learn domain invariant features for cross-scene…

计算机视觉与模式识别 · 计算机科学 2024-08-29 Jie Feng , Tianshu Zhang , Junpeng Zhang , Ronghua Shang , Weisheng Dong , Guangming Shi , Licheng Jiao

Deep learning models have demonstrated remarkable success in multi-organ segmentation but typically require large-scale datasets with all organs of interest annotated. However, medical image datasets are often low in sample size and only…

计算机视觉与模式识别 · 计算机科学 2023-11-03 Han Liu , Zhoubing Xu , Riqiang Gao , Hao Li , Jianing Wang , Guillaume Chabin , Ipek Oguz , Sasa Grbic

Spatial Transcriptomics is a novel technology that aligns histology images with spatially resolved gene expression profiles. Although groundbreaking, it struggles with gene capture yielding high corruption in acquired data. Given potential…

计算机视觉与模式识别 · 计算机科学 2024-09-30 Gabriel Mejia , Daniela Ruiz , Paula Cárdenas , Leonardo Manrique , Daniela Vega , Pablo Arbeláez

Spatial transcriptomics (ST) is an emerging technology that enables researchers to investigate the molecular relationships underlying tissue morphology. However, acquiring ST data remains prohibitively expensive, and traditional fixed-grid…

This paper presents Scalable Semantic Transfer (SST), a novel training paradigm, to explore how to leverage the mutual benefits of the data from different label domains (i.e. various levels of label granularity) to train a powerful human…

计算机视觉与模式识别 · 计算机科学 2023-04-11 Jie Yang , Chaoqun Wang , Zhen Li , Junle Wang , Ruimao Zhang

Microscopy-based phenotypic profiling is scalable for drug discovery but lacks the mechanistic depth of transcriptomics, which remains costly and scarce. Existing multimodal approaches either use images to support other modalities or…

计算机视觉与模式识别 · 计算机科学 2026-04-28 Jiayuan Chen , Ruoqi Liu , Zishan Gu , Ping Zhang

Unsupervised deep-learning (DL) models were recently proposed for deformable image registration tasks. In such models, a neural-network is trained to predict the best deformation field by minimizing some dissimilarity function between the…

计算机视觉与模式识别 · 计算机科学 2020-08-11 Samah Khawaled , Moti Freiman

Spatial transcriptomic (ST) clustering employs spatial and transcription information to group spots spatially coherent and transcriptionally similar together into the same spatial domain. Graph convolution network (GCN) and graph attention…

定量方法 · 定量生物学 2023-10-24 Chen Zhang , Junhui Gao , Lingxin Kong , Guangshuo cao , Xiangyu Guo , Wei Liu

The process of digitising histology slides involves multiple factors that can affect a whole slide image's (WSI) final appearance, including the staining protocol, scanner, and tissue type. This variability constitutes a domain shift and…

计算机视觉与模式识别 · 计算机科学 2024-11-26 Manahil Raza , Saad Bashir , Talha Qaiser , Nasir Rajpoot

Medical contrastive vision-language pre-training (VLP) has demonstrated significant potential in improving performance on downstream tasks. Traditional approaches typically employ contrastive learning, treating paired image-report samples…

计算机视觉与模式识别 · 计算机科学 2026-04-02 Phuoc-Nguyen Bui , Toan Duc Nguyen , Junghyun Bum , Duc-Tai Le , Hyunseung Choo

Efficient and accurate joint representation of a collection of images, that belong to the same class, is a major research challenge for practical image set classification. Existing methods either make prior assumptions about the data…

计算机视觉与模式识别 · 计算机科学 2015-04-02 Muhammad Uzair , Faisal Shafait , Bernard Ghanem , Ajmal Mian

Histopathology, particularly hematoxylin and eosin (H\&E) staining, plays a critical role in diagnosing and characterizing pathological conditions by highlighting tissue morphology. However, H\&E-stained images inherently lack molecular…

计算工程、金融与科学 · 计算机科学 2025-01-28 Qing Wang , Wen-jie Chen , Bo Li , Jing Su , Guangyu Wang , Qianqian Song

In this paper, we investigate the problem of hyperspectral (HS) image spatial super-resolution via deep learning. Particularly, we focus on how to embed the high-dimensional spatial-spectral information of HS images efficiently and…

计算机视觉与模式识别 · 计算机科学 2022-09-14 Jinhui Hou , Zhiyu Zhu , Junhui Hou , Huanqiang Zeng , Jinjian Wu , Jiantao Zhou