相关论文: KEDRec-LM: A Knowledge-distilled Explainable Drug …

Rare diseases affect hundreds of millions worldwide, yet diagnosis often spans years. Convectional pipelines decouple noisy evidence extraction from downstream inferential diagnosis, and general/medical large language models (LLMs) face…

Large language models (LLMs) demonstrate remarkable text comprehension and generation capabilities but often lack the ability to utilize up-to-date or domain-specific knowledge not included in their training data. To address this gap, we…

Innovation is a key driving force of human civilization. As the body of knowledge has grown considerably, bridging knowledge across different disciplines, where significant innovation often emerges, has become increasingly challenging. The…

The rapid advancement of large language models (LLMs) in biological-medical applications has highlighted a gap between their potential and the limited scale and often low quality of available open-source annotated textual datasets. In…

Benefiting from the strong reasoning capabilities, Large language models (LLMs) have demonstrated remarkable performance in recommender systems. Various efforts have been made to distill knowledge from LLMs to enhance collaborative models,…

In our study, we evaluated large language model (LLM) performance on pharmacy licensure-style question-answering tasks and developed an external knowledge integration method to improve accuracy. We benchmarked ten LLMs with varying…

Due to an exponential increase in published research articles, it is impossible for individual scientists to read all publications, even within their own research field. In this work, we investigate the use of large language models (LLMs)…

Sequential recommendation systems aim to predict users' next likely interaction based on their history. However, these systems face data sparsity and cold-start problems. Utilizing data from other domains, known as multi-domain methods, is…

Large Language Models (LLMs) have shown promise in character imitation, enabling immersive and engaging conversations. However, they often generate content that is irrelevant or inconsistent with a character's background. We attribute these…

In recent years, there has been growing interest in leveraging the impressive generalization capabilities and reasoning ability of large language models (LLMs) to improve the performance of recommenders. With this operation, recommenders…

The rapid expansion of publicly-available medical data presents a challenge for clinicians and researchers alike, increasing the gap between the volume of scientific literature and its applications. The steady growth of studies and findings…

The advancement of artificial intelligence algorithms has expanded their application to several fields such as the biomedical domain. Artificial intelligence systems, including Large Language Models (LLMs), can be particularly advantageous…

Large Language Model (LLM) has demonstrated significant success in a range of natural language processing (NLP) tasks within general domain. The emergence of LLM has introduced innovative methodologies across diverse fields, including the…

Large Language Models (LLMs) possess strong representation and reasoning capabilities, but their application to structure-based drug design (SBDD) is limited by insufficient understanding of protein structures and unpredictable molecular…

In this study, we reproduced the work done in the paper "XRec: Large Language Models for Explainable Recommendation" by Ma et al. (2024). The original authors introduced XRec, a model-agnostic collaborative instruction-tuning framework that…

Large language models (LLMs) have demonstrated remarkable capabilities across various NLP tasks. However, their computational costs are prohibitively high. To address this issue, previous research has attempted to distill the knowledge of…

As large language models (LLMs) continue to grow in size, their abilities to tackle complex tasks have significantly improved. However, issues such as hallucination and the lack of up-to-date knowledge largely remain unresolved. Knowledge…

Finetuning a Large Language Model (LLM) is crucial for generating results towards specific objectives. This research delves into the realm of drug optimization and introduce a novel reinforcement learning algorithm to finetune a drug…

The automatic construction of knowledge graphs (KGs) is an important research area in medicine, with far-reaching applications spanning drug discovery and clinical trial design. These applications hinge on the accurate identification of…

There is vivid research on adapting Large Language Models (LLMs) to perform a variety of tasks in high-stakes domains such as healthcare. Despite their popularity, there is a lack of understanding of the extent and contributing factors that…