相关论文: Overconfident Oracles: Limitations of In Silico Se…

Machine learning may enable the automated generation of test oracles. We have characterized emerging research in this area through a systematic literature review examining oracle types, researcher goals, the ML techniques applied, how the…

We investigate the design challenges of constructing effective and efficient neural sequence labeling systems, by reproducing twelve neural sequence labeling models, which include most of the state-of-the-art structures, and conduct a…

Machine learning contrasts with traditional software development in that the oracle is the data, and the data is not always a correct representation of the problem that machine learning tries to model. We present a survey of the oracle…

The ability to design and optimize biological sequences with specific functionalities would unlock enormous value in technology and healthcare. In recent years, machine learning-guided sequence design has progressed this goal significantly,…

A clinical trial is an essential step in drug development, which is often costly and time-consuming. In silico trials are clinical trials conducted digitally through simulation and modeling as an alternative to traditional clinical trials.…

In-context learning (ICL) enables large language models to perform new tasks by conditioning on a sequence of examples. Most prior work reasonably and intuitively assumes that which examples are chosen has a far greater effect on…

The effectiveness of a test suite in detecting faults highly depends on the correctness and completeness of its test oracles. Large Language Models (LLMs) have already demonstrated remarkable proficiency in tackling diverse software testing…

Benchmarks shape scientific conclusions about model capabilities and steer model development. This creates a feedback loop: stronger benchmarks drive better models, and better models demand more discriminative benchmarks. Ensuring benchmark…

Code coverage is a popular and widespread test adequacy metric that measures the percentage of program codes executed by a test suite. Despite its popularity, code coverage has several limitations. One of the major limitations is that it…

Different research communities have developed various approaches to assess the credibility of predictive models. Each approach usually works well for a specific type of model, and under some epistemic conditions that are normally satisfied…

The scaling law, which indicates that model performance improves with increasing dataset and model capacity, has fueled a growing trend in expanding recommendation models in both industry and academia. However, the advent of large-scale…

As machine learning (ML) systems increasingly permeate high-stakes settings such as healthcare, transportation, military, and national security, concerns regarding their reliability have emerged. Despite notable progress, the performance of…

The task of assigning label sequences to a set of observed sequences is common in computational linguistics. Several models for sequence labeling have been proposed over the last few years. Here, we focus on discriminative models for…

Protein sequence optimization under tight oracle budgets requires methods that explore vast combinatorial spaces while making each evaluation informative. Existing reinforcement learning and off-policy generative approaches often degrade…

Applying machine learning to biological sequences - DNA, RNA and protein - has enormous potential to advance human health, environmental sustainability, and fundamental biological understanding. However, many existing machine learning…

The development and deployment of systems using supervised machine learning (ML) remain challenging: mainly due to the limited reliability of prediction models and the lack of knowledge on how to effectively integrate human intelligence…

The rapid integration of machine learning (ML) predictors into in silico medicine has revolutionized the estimation of quantities of interest (QIs) that are otherwise challenging to measure directly. However, the credibility of these…

Software testing remains the most widely used methodology for validating quality of code. However, effectiveness of testing critically depends on the quality of test suites used. Test cases in a test suite consist of two fundamental parts:…

Material scientists are increasingly adopting the use of machine learning (ML) for making potentially important decisions, such as, discovery, development, optimization, synthesis and characterization of materials. However, despite ML's…

The use of black-box optimization for the design of new biological sequences is an emerging research area with potentially revolutionary impact. The cost and latency of wet-lab experiments requires methods that find good sequences in few…