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Biomedical networks (or graphs) are universal descriptors for systems of interacting elements, from molecular interactions and disease co-morbidity to healthcare systems and scientific knowledge. Advances in artificial intelligence,…

机器学习 · 计算机科学 2025-02-07 Michelle M. Li , Kexin Huang , Marinka Zitnik

The prevalence of employing attention mechanisms has brought along concerns on the interpretability of attention distributions. Although it provides insights about how a model is operating, utilizing attention as the explanation of model…

计算机视觉与模式识别 · 计算机科学 2022-09-16 Tristan Gomez , Suiyi Ling , Thomas Fréour , Harold Mouchère

Alterations in the geometry and function of the heart define well-established causes of cardiovascular disease. However, current approaches to the diagnosis of cardiovascular diseases often rely on subjective human assessment as well as…

Graph Neural Networks have been widely applied in critical decision-making areas that demand interpretable predictions, leading to the flourishing development of interpretability algorithms. However, current graph interpretability…

机器学习 · 计算机科学 2024-09-04 Xiaodi Li , Jianfeng Gui , Qian Gao , Haoyuan Shi , Zhenyu Yue

Interpretability of deep neural networks (DNNs) is essential since it enables users to understand the overall strengths and weaknesses of the models, conveys an understanding of how the models will behave in the future, and how to diagnose…

计算机视觉与模式识别 · 计算机科学 2017-03-31 Yinpeng Dong , Hang Su , Jun Zhu , Bo Zhang

Deep neural networks and other sophisticated machine learning models are widely applied to biomedical signal data because they can detect complex patterns and compute accurate predictions. However, the difficulty of interpreting such models…

信号处理 · 电气工程与系统科学 2021-07-12 Charmaine Chia , Matteo Sesia , Chi-Sing Ho , Stefanie S. Jeffrey , Jennifer Dionne , Emmanuel J. Candès , Roger T. Howe

Linear models are widely used in computational neuroimaging to identify biomarkers associated with brain pathologies. However, interpreting the learned weights remains challenging, as they do not always yield clinically meaningful insights.…

机器学习 · 计算机科学 2026-04-23 Sara Petiton , Antoine Grigis , Raphaël Vock , Edouard Duchesnay

Diabetic Retinopathy (DR) is a constantly deteriorating disease, being one of the leading causes of vision impairment and blindness. Subtle distinction among different grades and existence of many significant small features make the task of…

计算机视觉与模式识别 · 计算机科学 2018-12-31 Sheikh Muhammad Saiful Islam , Md Mahedi Hasan , Sohaib Abdullah

Optical coherence tomography (OCT), a commonly used retinal imaging modality, plays a central role in retinal disease diagnosis by providing high-resolution visualization of retinal layers. While deep learning (DL) has achieved expert-level…

计算机视觉与模式识别 · 计算机科学 2026-05-05 Tienyu Chang , Tianhao Li , Ruogu Fang , Jiang Bian , Yu Huang

For Artificial Intelligence to have a greater impact in biology and medicine, it is crucial that recommendations are both accurate and transparent. In other domains, a neurosymbolic approach of multi-hop reasoning on knowledge graphs has…

机器学习 · 计算机科学 2022-10-10 Gavin Edwards , Sebastian Nilsson , Benedek Rozemberczki , Eliseo Papa

Nowadays, neural network (NN) and deep learning (DL) techniques are widely adopted in many applications, including recommender systems. Given the sparse and stochastic nature of collaborative filtering (CF) data, recent works have…

信息检索 · 计算机科学 2024-07-03 Giuseppe Serra , Peter Tino , Zhao Xu , Xin Yao

Accurate and interpretable diagnostic models are crucial in the safety-critical field of medicine. We investigate the interpretability of our proposed biomarker-based lung ultrasound diagnostic pipeline to enhance clinicians' diagnostic…

Accurate skin disease classification is a critical yet challenging task due to high inter-class similarity, intra-class variability, and complex lesion textures. While deep learning-based computer-aided diagnosis (CAD) systems have shown…

计算机视觉与模式识别 · 计算机科学 2025-08-07 Enam Ahmed Taufik , Abdullah Khondoker , Antara Firoz Parsa , Seraj Al Mahmud Mostafa

Dementia is a progressive neurodegenerative disorder with multiple etiologies, including Alzheimer's disease, Parkinson's disease, frontotemporal dementia, and vascular dementia. Its clinical and biological heterogeneity makes diagnosis and…

机器学习 · 计算机科学 2025-09-24 Niharika Tewari , Nguyen Linh Dan Le , Mujie Liu , Jing Ren , Ziqi Xu , Tabinda Sarwar , Veeky Baths , Feng Xia

Convolutional neural networks (CNNs) show impressive performance for image classification and detection, extending heavily to the medical image domain. Nevertheless, medical experts are sceptical in these predictions as the nonlinear…

计算机视觉与模式识别 · 计算机科学 2017-06-30 Waleed M. Gondal , Jan M. Köhler , René Grzeszick , Gernot A. Fink , Michael Hirsch

Retinal vascular diseases affect the well-being of human body and sometimes provide vital signs of otherwise undetected bodily damage. Recently, deep learning techniques have been successfully applied for detection of diabetic retinopathy…

机器学习 · 计算机科学 2022-01-05 Guan Wang , Yusuke Kikuchi , Jinglin Yi , Qiong Zou , Rui Zhou , Xin Guo

Graph neural networks (GNNs) are highly effective on a variety of graph-related tasks; however, they lack interpretability and transparency. Current explainability approaches are typically local and treat GNNs as black-boxes. They do not…

机器学习 · 计算机科学 2023-03-10 Han Xuanyuan , Pietro Barbiero , Dobrik Georgiev , Lucie Charlotte Magister , Pietro Lió

Interpretable models are crucial for supporting clinical decision-making, driving advances in their development and application for medical images. However, the nature of 3D volumetric data makes it inherently challenging to visualize and…

图形学 · 计算机科学 2025-06-26 Fabian Bongratz , Tom Nuno Wolf , Jaume Gual Ramon , Christian Wachinger

Integrating multi-omics data, such as DNA methylation, mRNA expression, and microRNA (miRNA) expression, offers a comprehensive view of the biological mechanisms underlying disease. However, the high dimensionality of multi-omics data, the…

机器学习 · 计算机科学 2026-02-12 Tiantian Yang , Zhiqian Chen

Diabetic retinopathy (DR) is a growing health problem worldwide and is a leading cause of visual impairment and blindness, especially among working people aged 20-65. Its incidence is increasing along with the number of diabetes cases, and…

图像与视频处理 · 电气工程与系统科学 2023-12-04 Agnieszka Cisek , Karolina Korycinska , Leszek Pyziak , Marzena Malicka , Tomasz Wiecek , Grzegorz Gruzel , Kamil Szmuc , Jozef Cebulski , Mariusz Spyra