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The majority of cancer treatments end in failure due to Intra-Tumor Heterogeneity (ITH). ITH in cancer is represented by clonal evolution where different sub-clones compete with each other for resources under conditions of Darwinian natural…

Risk stratification (characterization) of tumors from radiology images can be more accurate and faster with computer-aided diagnosis (CAD) tools. Tumor characterization through such tools can also enable non-invasive cancer staging,…

计算机视觉与模式识别 · 计算机科学 2019-01-21 Sarfaraz Hussein , Pujan Kandel , Candice W. Bolan , Michael B. Wallace , Ulas Bagci

At present, the incidence and fatality rate of lung cancer in China rank first among all malignant tumors. Despite the continuous development and improvement of China's medical level, the overall 5-year survival rate of lung cancer patients…

医学物理 · 物理学 2024-02-08 Shulin Li , Liqiang Yu , Bo Liu , Qunwei Lin , Jiaxin Huang

Lung cancer has been one of the most prevalent disease in recent years. According to the research of this field, more than 200,000 cases are identified each year in the US. Uncontrolled multiplication and growth of the lung cells result in…

图像与视频处理 · 电气工程与系统科学 2022-01-04 Hesamoddin Hosseini , Reza Monsefi , Shabnam Shadroo

Cancer drug response prediction (DRP) models present a promising approach towards precision oncology, tailoring treatments to individual patient profiles. While deep learning (DL) methods have shown great potential in this area, models that…

Prognosis prediction is crucial for determining optimal treatment plans for lung cancer patients. Traditionally, such predictions relied on models developed from retrospective patient data. Recently, large language models (LLMs) have gained…

计算与语言 · 计算机科学 2024-08-16 Danqing Hu , Bing Liu , Xiang Li , Xiaofeng Zhu , Nan Wu

Introduction: Cases of throat cancer are rising worldwide. With survival decreasing significantly at later stages, early detection is vital. Artificial intelligence (AI) and machine learning (ML) have the potential to detect throat cancer…

机器学习 · 计算机科学 2025-05-14 Mary Paterson , James Moor , Luisa Cutillo

Clinical management of cancer has continuously evolved for several decades. Biochemical, molecular and genomics approaches have brought and still bring numerous insights into cancerous diseases. It is now accepted that some phenomena,…

Biochemical recurrence (BCR) after radical prostatectomy (RP) is a surrogate marker for aggressive prostate cancer with adverse outcomes, yet current prognostic tools remain imprecise. We trained an AI-based model on diagnostic prostate…

The nature of clinical data makes it difficult to quickly select, tune and apply machine learning algorithms to clinical prognosis. As a result, a lot of time is spent searching for the most appropriate machine learning algorithms…

机器学习 · 计算机科学 2015-04-21 Kwetishe Joro Danjuma

Although cancer patients survive years after oncologic therapy, they are plagued with long-lasting or permanent residual symptoms, whose severity, rate of development, and resolution after treatment vary largely between survivors. The…

Prognostic evaluation in patients with colorectal liver metastases (CRLM) remains challenging due to suboptimal accuracy of conventional clinical models. This study developed and validated a robust machine learning model for predicting…

图像与视频处理 · 电气工程与系统科学 2025-07-29 Qinlong Li , Pu Sun , Guanlin Zhu , Tianjiao Liang , Honggang QI

Non-muscle-invasive bladder cancer (NMIBC) is a relentless challenge in oncology, with recurrence rates soaring as high as 70-80%. Each recurrence triggers a cascade of invasive procedures, lifelong surveillance, and escalating healthcare…

机器学习 · 计算机科学 2025-05-02 Saram Abbas , Naeem Soomro , Rishad Shafik , Rakesh Heer , Kabita Adhikari

Women with an increased life-time risk of breast cancer undergo supplemental annual screening MRI. We propose to predict the risk of developing breast cancer within one year based on the current MRI, with the objective of reducing screening…

The choice of the most effective treatment may eventually be influenced by breast cancer survival prediction. To predict the chances of a patient surviving, a variety of techniques were employed, such as statistical, machine learning, and…

机器学习 · 计算机科学 2023-04-18 Khaoula Chtouki , Maryem Rhanoui , Mounia Mikram , Kamelia Amazian , Siham Yousfi

Lung cancer is the second most common cancer and the leading cause of cancer-related deaths worldwide. Survival largely depends on tumor stage at diagnosis, and early detection with low-dose CT can significantly reduce mortality in…

Cancer is one of the most life-threatening diseases worldwide, and head and neck (H&N) cancer is a prevalent type with hundreds of thousands of new cases recorded each year. Clinicians use medical imaging modalities such as computed…

图像与视频处理 · 电气工程与系统科学 2023-06-02 Ikboljon Sobirov

Personalized head and neck cancer therapeutics have greatly improved survival rates for patients, but are often leading to understudied long-lasting symptoms which affect quality of life. Sequential rule mining (SRM) is a promising…

In this chapter, we provide a brief overview of applying machine learning techniques for clinical prediction tasks. We begin with a quick introduction to the concepts of machine learning and outline some of the most common machine learning…

机器学习 · 计算机科学 2019-09-23 Wei-Hung Weng

Pancreatic cancers have one of the worst prognoses compared to other cancers, as they are diagnosed when cancer has progressed towards its latter stages. The current manual histological grading for diagnosing pancreatic adenocarcinomas is…

图像与视频处理 · 电气工程与系统科学 2022-06-20 Biraja Ghoshal , Bhargab Ghoshal , Allan Tucker