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Longitudinal neuroimaging is essential for modeling disease progression in Alzheimer's disease (AD), yet irregular sampling and missing visits pose substantial challenges for learning reliable temporal representations. To address this…

机器学习 · 计算机科学 2026-03-24 Ruiying Chen , Yutong Wang , Houliang Zhou , Wei Liang , Yong Chen , Lifang He

Epilepsy is a disorder characterised by spontaneous, recurrent seizures. Both local and network abnormalities have been associated with epilepsy, and the exact processes generating seizures are thought to be heterogeneous and…

神经元与认知 · 定量生物学 2019-01-07 Yujiang Wang , Gabrielle Marie Schroeder , Nishant Sinha , Peter Neal Taylor

The accurate diagnosis of Alzheimer's disease (AD) and prognosis of mild cognitive impairment (MCI) conversion are crucial for early intervention. However, existing multimodal methods face several challenges, from the heterogeneity of input…

机器学习 · 计算机科学 2025-03-20 Chenyu Liu , Luca Rossi

Traditional functional connectivity based on functional magnetic resonance imaging (fMRI) can only capture pairwise interactions between brain regions. Hypergraphs, which reveal high-order relationships among multiple brain regions, have…

神经元与认知 · 定量生物学 2025-05-20 Wenqi Hu , Xuerui Su , Guanliang Li , Yidi Pan , Aijing Lin

Electronic Health Records (EHRs) provide vital contextual information to radiologists and other physicians when making a diagnosis. Unfortunately, because a given patient's record may contain hundreds of notes and reports, identifying…

We present a comprehensive analysis of deep learning approaches for Electronic Health Record (EHR) time-series imputation, examining how architectural and framework biases combine to influence model performance. Our investigation reveals…

机器学习 · 计算机科学 2025-02-05 Linglong Qian , Tao Wang , Jun Wang , Hugh Logan Ellis , Robin Mitra , Richard Dobson , Zina Ibrahim

Tabular datasets with low-sample-size or many variables are prevalent in biomedicine. Practitioners in this domain prefer linear or tree-based models over neural networks since the latter are harder to interpret and tend to overfit when…

机器学习 · 计算机科学 2022-02-09 Junchen Yang , Ofir Lindenbaum , Yuval Kluger

Interpretable brain network models for disease prediction are of great value for the advancement of neuroscience. GNNs are promising to model complicated network data, but they are prone to overfitting and suffer from poor interpretability,…

机器学习 · 计算机科学 2021-07-13 Hejie Cui , Wei Dai , Yanqiao Zhu , Xiaoxiao Li , Lifang He , Carl Yang

Even though neural networks have been long deployed in applications involving tabular data, still existing neural architectures are not explainable by design. In this paper, we propose a new class of interpretable neural networks for…

机器学习 · 计算机科学 2024-10-31 Arlind Kadra , Sebastian Pineda Arango , Josif Grabocka

With the recent availability of Electronic Health Records (EHR) and great opportunities they offer for advancing medical informatics, there has been growing interest in mining EHR for improving quality of care. Disease diagnosis due to its…

人工智能 · 计算机科学 2018-04-24 Anahita Hosseini , Ting Chen , Wenjun Wu , Yizhou Sun , Majid Sarrafzadeh

Quantification of anatomical shape changes currently relies on scalar global indexes which are largely insensitive to regional or asymmetric modifications. Accurate assessment of pathology-driven anatomical remodeling is a crucial step for…

In mission-critical domains such as law enforcement and medical diagnosis, the ability to explain and interpret the outputs of deep learning models is crucial for ensuring user trust and supporting informed decision-making. Despite…

计算机视觉与模式识别 · 计算机科学 2024-11-07 Bharat Chandra Yalavarthi , Nalini Ratha

This paper explores the applications and challenges of graph neural networks (GNNs) in processing complex graph data brought about by the rapid development of the Internet. Given the heterogeneity and redundancy problems that graph data…

机器学习 · 计算机科学 2024-10-24 Jianjun Wei , Yue Liu , Xin Huang , Xin Zhang , Wenyi Liu , Xu Yan

In this work, we propose a novel segmental hypergraph representation to model overlapping entity mentions that are prevalent in many practical datasets. We show that our model built on top of such a new representation is able to capture…

计算与语言 · 计算机科学 2018-10-04 Bailin Wang , Wei Lu

Although neural networks have seen tremendous success as predictive models in a variety of domains, they can be overly confident in their predictions on out-of-distribution (OOD) data. To be viable for safety-critical applications, like…

机器人学 · 计算机科学 2022-11-17 Masha Itkina , Mykel J. Kochenderfer

In this paper, our focus is on constructing models to assist a clinician in the diagnosis of COVID-19 patients in situations where it is easier and cheaper to obtain X-ray data than to obtain high-quality images like those from CT scans.…

图像与视频处理 · 电气工程与系统科学 2021-02-15 Rishab Khincha , Soundarya Krishnan , Tirtharaj Dash , Lovekesh Vig , Ashwin Srinivasan

Trust and credibility in machine learning models is bolstered by the ability of a model to explain itsdecisions. While explainability of deep learning models is a well-known challenge, a further chal-lenge is clarity of the explanation…

机器学习 · 计算机科学 2020-11-30 hsan Ullah , Andre Rios , Vaibhav Gala , Susan Mckeever

Interpretable deep learning is a fundamental building block towards safer AI, especially when the deployment possibilities of deep learning-based computer-aided medical diagnostic systems are so eminent. However, without a computational…

机器学习 · 计算机科学 2018-06-27 Anirban Mukhopadhyay

The automation of the medical evidence acquisition and diagnosis process has recently attracted increasing attention in order to reduce the workload of doctors and democratize access to medical care. However, most works proposed in the…

计算与语言 · 计算机科学 2022-10-14 Arsene Fansi Tchango , Rishab Goel , Julien Martel , Zhi Wen , Gaetan Marceau Caron , Joumana Ghosn

We propose a Healthcare Graph Convolutional Network (HealGCN) to offer disease self-diagnosis service for online users based on Electronic Healthcare Records (EHRs). Two main challenges are focused in this paper for online disease…

机器学习 · 计算机科学 2021-02-16 Zifeng Wang , Rui Wen , Xi Chen , Shilei Cao , Shao-Lun Huang , Buyue Qian , Yefeng Zheng