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Deep neural networks are increasingly applied in automated histopathology. Yet, whole-slide images (WSIs) are often acquired at gigapixel sizes, rendering them computationally infeasible to analyze entirely at high resolution. Diagnostic…

图像与视频处理 · 电气工程与系统科学 2026-02-10 Tarun G , Naman Malpani , Gugan Thoppe , Sridharan Devarajan

The remarkable success of deep learning has prompted interest in its application to medical imaging diagnosis. Even though state-of-the-art deep learning models have achieved human-level accuracy on the classification of different types of…

图像与视频处理 · 电气工程与系统科学 2023-09-20 Cristiano Patrício , João C. Neves , Luís F. Teixeira

We developed an explainable artificial intelligence (AI) early warning score (xAI-EWS) system for early detection of acute critical illness. While maintaining a high predictive performance, our system explains to the clinician on which…

In this work, we study the problem pertaining to personalized classification of subclinical atherosclerosis by developing a hierarchical graph neural network framework to leverage two characteristic modalities of a patient: clinical…

机器学习 · 计算机科学 2025-09-15 Irsyad Adam , Steven Swee , Erika Yilin , Ethan Ji , William Speier , Dean Wang , Alex Bui , Wei Wang , Karol Watson , Peipei Ping

Deep learning has excelled in medical image classification, but its clinical application is limited by poor interpretability. Capsule networks, known for encoding hierarchical relationships and spatial features, show potential in addressing…

计算机视觉与模式识别 · 计算机科学 2024-11-05 Xinyu Geng , Jiaming Wang , Jun Xu

As interpretability has been pointed out as the obstacle to the adoption of Deep Neural Networks (DNNs), there is an increasing interest in solving a transparency issue to guarantee the impressive performance. In this paper, we demonstrate…

图像与视频处理 · 电气工程与系统科学 2021-07-20 Woo-Jeoung Nam , Seong-Whan Lee

The interpretability of deep neural networks has become a subject of great interest within the medical and healthcare domain. This attention stems from concerns regarding transparency, legal and ethical considerations, and the medical…

图像与视频处理 · 电气工程与系统科学 2023-11-20 Mahbub Ul Alam , Jaakko Hollmén , Jón Rúnar Baldvinsson , Rahim Rahmani

With the wide application of electronic health records (EHR) in healthcare facilities, health event prediction with deep learning has gained more and more attention. A common feature of EHR data used for deep-learning-based predictions is…

机器学习 · 计算机科学 2021-12-17 Chang Lu , Tian Han , Yue Ning

With the advent of high-throughput sequencing (HTS) in molecular biology and medicine, the need for scalable statistical solutions for modeling complex biological systems has become of critical importance. The increasing number of platforms…

分子网络 · 定量生物学 2022-10-19 Fernando Palluzzi , Mario Grassi

The Intensive Care Unit (ICU) is one of the most important parts of a hospital, which admits critically ill patients and provides continuous monitoring and treatment. Various patient outcome prediction methods have been attempted to assist…

机器学习 · 计算机科学 2023-10-24 Yuxi Liu , Zhenhao Zhang , Shaowen Qin , Flora D. Salim , Antonio Jimeno Yepes , Jun Shen , Jiang Bian

Deep neural networks excel in radiological image classification but frequently suffer from poor interpretability, limiting clinical acceptance. We present MedicalPatchNet, an inherently self-explainable architecture for chest X-ray…

计算机视觉与模式识别 · 计算机科学 2026-02-26 Patrick Wienholt , Christiane Kuhl , Jakob Nikolas Kather , Sven Nebelung , Daniel Truhn

Electronic Health Records (EHRs), comprising diverse clinical data such as diagnoses, medications, and laboratory results, hold great promise for translational research. EHR-derived data have advanced disease prevention, improved clinical…

机器学习 · 统计学 2025-09-09 Yinjie Wang , Doudou Zhou , Yue Liu , Junwei Lu , Tianxi Cai

Despite the Graph Neural Networks' (GNNs) proficiency in analyzing graph data, achieving high-accuracy and interpretable predictions remains challenging. Existing GNN interpreters typically provide post-hoc explanations disjointed from…

机器学习 · 计算机科学 2024-07-26 Zhenhua Huang , Kunhao Li , Shaojie Wang , Zhaohong Jia , Wentao Zhu , Sharad Mehrotra

The widespread availability of electronic health records (EHRs) promises to usher in the era of personalized medicine. However, the problem of extracting useful clinical representations from longitudinal EHR data remains challenging. In…

机器学习 · 计算机科学 2017-01-27 Zhengping Che , Yu Cheng , Zhaonan Sun , Yan Liu

Major postoperative complications are devastating to surgical patients. Some of these complications are potentially preventable via early predictions based on intraoperative data. However, intraoperative data comprise long and fine-grained…

机器学习 · 计算机科学 2022-10-11 Dingwen Li , Bing Xue , Christopher King , Bradley Fritz , Michael Avidan , Joanna Abraham , Chenyang Lu

The proliferation of high-dimensional datasets in fields such as genomics, healthcare, and finance has created an urgent need for machine learning models that are both highly accurate and inherently interpretable. While traditional deep…

机器学习 · 计算机科学 2025-10-28 Rekha R Nair , Tina Babu , Alavikunhu Panthakkan , Hussain Al-Ahmad , Balamurugan Balusamy

Recently, significant attention has been given to the idea of viewing relational databases as heterogeneous graphs, enabling the application of graph neural network (GNN) technology for predictive tasks. However, existing GNN methods…

机器学习 · 计算机科学 2025-02-26 Francesco Ferrini , Antonio Longa , Andrea Passerini , Manfred Jaeger

Recent advancements in Graph Neural Networks (GNNs) have spurred an upsurge of research dedicated to enhancing the explainability of GNNs, particularly in critical domains such as medicine. A promising approach is the self-explaining…

机器学习 · 计算机科学 2024-08-15 Jingyu Peng , Qi Liu , Linan Yue , Zaixi Zhang , Kai Zhang , Yunhao Sha

Advancements in deep learning have enabled highly accurate arrhythmia detection from electrocardiogram (ECG) signals, but limited interpretability remains a barrier to clinical adoption. This study investigates the application of…

机器学习 · 计算机科学 2025-08-26 Joschka Beck , Arlene John

Ubiquitous bio-sensing for personalized health monitoring is slowly becoming a reality with the increasing availability of small, diverse, robust, high fidelity sensors. This oncoming flood of data begs the question of how we will extract…

计算机视觉与模式识别 · 计算机科学 2017-08-29 JT Turner , Adam Page , Tinoosh Mohsenin , Tim Oates