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Patients with Frontotemporal Dementia (FTD) have impaired cognitive abilities, executive and behavioral traits, loss of language ability, and decreased memory capabilities. Based on the distinct patterns of cortical atrophy and symptoms,…

人工智能 · 计算机科学 2021-04-13 Km Poonam , Rajlakshmi Guha , Partha P Chakrabarti

Speech-based detection of cognitive impairment (CI) offers a promising non-invasive approach for early diagnosis, yet performance disparities across demographic and clinical subgroups remain underexplored, raising concerns around fairness…

音频与语音处理 · 电气工程与系统科学 2026-03-04 Kashaf Gulzar , Korbinian Riedhammer , Elmar Nöth , Andreas K. Maier , Paula Andrea Pérez-Toro

Depression is a mental disorder and can cause a variety of symptoms, including psychological, physical, and social. Speech has been proved an objective marker for the early recognition of depression. For this reason, many studies have been…

机器学习 · 计算机科学 2026-05-12 Loukas Ilias , Dimitris Askounis

Multimodal depression classification has gained immense popularity over the recent years. We develop a multimodal depression classification system using articulatory coordination features extracted from vocal tract variables and text…

音频与语音处理 · 电气工程与系统科学 2022-02-15 Nadee Seneviratne , Carol Espy-Wilson

Timely and accurate assessment of cognitive impairment remains a major unmet need. Speech biomarkers offer a scalable, non-invasive, cost-effective solution for automated screening. However, the clinical utility of machine learning (ML)…

Deep learning has been successful in predicting neurodegenerative disorders, such as Alzheimer's disease, from magnetic resonance imaging (MRI). Combining multiple imaging modalities, such as T1-weighted (T1) and diffusion-weighted imaging…

Speech pauses, alongside content and structure, offer a valuable and non-invasive biomarker for detecting dementia. This work investigates the use of pause-enriched transcripts in transformer-based language models to differentiate the…

音频与语音处理 · 电气工程与系统科学 2024-08-28 Franziska Braun , Sebastian P. Bayerl , Florian Hönig , Hartmut Lehfeld , Thomas Hillemacher , Tobias Bocklet , Korbinian Riedhammer

Aphasia is a language disorder that affects the speaking ability of millions of patients. This paper presents a new benchmark for Aphasia speech recognition and detection tasks using state-of-the-art speech recognition techniques with the…

音频与语音处理 · 电气工程与系统科学 2023-05-24 Jiyang Tang , William Chen , Xuankai Chang , Shinji Watanabe , Brian MacWhinney

The analysis of speech in individuals with amyotrophic lateral sclerosis is a powerful tool to support clinicians in the assessment of bulbar dysfunction. However, current methods used in clinical practice consist of subjective evaluations…

音频与语音处理 · 电气工程与系统科学 2025-05-28 Francesco Pierotti , Andrea Bandini

Early dementia diagnosis requires biomarkers sensitive to both structural and functional brain changes. While structural neuroimaging biomarkers have progressed significantly, objective functional biomarkers of early cognitive decline…

神经元与认知 · 定量生物学 2025-04-16 Tomasz M. Rutkowski , Stanisław Narębski , Mihoko Otake-Matsuura , Tomasz Komendziński

Speaker embeddings extracted from voice recordings have been proven valuable for dementia detection. However, by their nature, these embeddings contain identifiable information which raises privacy concerns. In this work, we aim to…

声音 · 计算机科学 2024-07-08 Dominika Woszczyk , Ranya Aloufi , Soteris Demetriou

Speech pause is an effective biomarker in dementia detection. Recent deep learning models have exploited speech pauses to achieve highly accurate dementia detection, but have not exploited the interpretability of speech pauses, i.e., what…

计算与语言 · 计算机科学 2021-11-16 Youxiang Zhu , Bang Tran , Xiaohui Liang , John A. Batsis , Robert M. Roth

Alzheimer's disease is a progressive neurological disorder characterized by cognitive impairment and memory loss. With the increasing aging population, the incidence of AD is continuously rising, making early diagnosis and intervention an…

图像与视频处理 · 电气工程与系统科学 2023-11-23 Guian Fang , Mengsha Liu , Yi Zhong , Zhuolin Zhang , Jiehui Huang , Zhenchao Tang , Calvin Yu-Chian Chen

Dementia is a leading cause of diseases for the elderly. Early diagnosis is very important for the elderly living with dementias. In this paper, we propose a method for dementia diagnosis by predicting MMSE score from finger-tapping…

定量方法 · 定量生物学 2021-11-17 Jian Ma

As the aging of society continues to accelerate, Alzheimer's Disease (AD) has received more and more attention from not only medical but also other fields, such as computer science, over the past decade. Since speech is considered one of…

机器人学 · 计算机科学 2022-11-17 Yuanchao Li , Catherine Lai , Divesh Lala , Koji Inoue , Tatsuya Kawahara

Early diagnosis of Alzheimer's disease and its prodromal stage, also known as mild cognitive impairment (MCI), is critical since some patients with progressive MCI will develop the disease. We propose a multi-stream deep convolutional…

图像与视频处理 · 电气工程与系统科学 2023-08-01 Mona Ashtari-Majlan , Abbas Seifi , Mohammad Mahdi Dehshibi

Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects cognitive functions such as memory, thinking, and behavior. In this disease, there is a critical phase, mild cognitive impairment, that is really…

信号处理 · 电气工程与系统科学 2024-04-02 Arezoo Borji , Taha-Hossein Hejazi , Abbas Seifi

The automated evaluation of cognitive status utilizing multimedia technologies presents a promising frontier in early dementia diagnosis. However, the development of robust machine learning models for cognitive impairment detection is…

数据库 · 计算机科学 2026-04-03 Liuyu Wu , Rui Feng , Jie Li , Wentao Xiang , Yi Zhang , Yin Cao , Siyang Song , Xiao Gu , Jianqing Li , Wei Wang

A significant number of studies apply acoustic and linguistic characteristics of human speech as prominent markers of dementia and depression. However, studies on discriminating depression from dementia are rare. Co-morbid depression is…

计算与语言 · 计算机科学 2022-10-10 Malikeh Ehghaghi , Frank Rudzicz , Jekaterina Novikova

Interpreting the environmental, behavioural and psychological data from in-home sensory observations and measurements can provide valuable insights into the health and well-being of individuals. Presents of neuropsychiatric and…

信号处理 · 电气工程与系统科学 2021-05-24 Roonak Rezvani , Samaneh Kouchaki , Ramin Nilforooshan , David J. Sharp , Payam Barnaghi