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In multi-class histopathology nuclei analysis tasks, the lack of training data becomes a main bottleneck for the performance of learning-based methods. To tackle this challenge, previous methods have utilized generative models to increase…

计算机视觉与模式识别 · 计算机科学 2024-09-05 Seonghui Min , Hyun-Jic Oh , Won-Ki Jeong

Deep learning based medical image recognition systems often require a substantial amount of training data with expert annotations, which can be expensive and time-consuming to obtain. Recently, synthetic augmentation techniques have been…

计算机视觉与模式识别 · 计算机科学 2023-08-09 Jiarong Ye , Haomiao Ni , Peng Jin , Sharon X. Huang , Yuan Xue

Histopathological image segmentation is a laborious and time-intensive task, often requiring analysis from experienced pathologists for accurate examinations. To reduce this burden, supervised machine-learning approaches have been adopted…

计算机视觉与模式识别 · 计算机科学 2024-09-12 Vishnuvardhan Purma , Suhas Srinath , Seshan Srirangarajan , Aanchal Kakkar , Prathosh A. P

Automatic histopathology image segmentation is crucial to disease analysis. Limited available labeled data hinders the generalizability of trained models under the fully supervised setting. Semi-supervised learning (SSL) based on generative…

计算机视觉与模式识别 · 计算机科学 2020-12-18 Hongxiao Wang , Hao Zheng , Jianxu Chen , Lin Yang , Yizhe Zhang , Danny Z. Chen

Nuclei segmentation is a fundamental but challenging task in the quantitative analysis of histopathology images. Although fully-supervised deep learning-based methods have made significant progress, a large number of labeled images are…

图像与视频处理 · 电气工程与系统科学 2024-01-22 Xinyi Yu , Guanbin Li , Wei Lou , Siqi Liu , Xiang Wan , Yan Chen , Haofeng Li

To achieve high-quality results, diffusion models must be trained on large datasets. This can be notably prohibitive for models in specialized domains, such as computational pathology. Conditioning on labeled data is known to help in…

计算机视觉与模式识别 · 计算机科学 2023-12-04 Srikar Yellapragada , Alexandros Graikos , Prateek Prasanna , Tahsin Kurc , Joel Saltz , Dimitris Samaras

Histopathology image classification is crucial for the accurate identification and diagnosis of various diseases but requires large and diverse datasets. Obtaining such datasets, however, is often costly and time-consuming due to the need…

计算机视觉与模式识别 · 计算机科学 2024-09-25 Leire Benito-Del-Valle , Aitor Alvarez-Gila , Itziar Eguskiza , Cristina L. Saratxaga

Mitotic figure detection in histology images is a hard-to-define, yet clinically significant task, where labels are generated with pathologist interpretations and where there is no ``gold-standard'' independent ground-truth. However, it is…

计算机视觉与模式识别 · 计算机科学 2023-10-09 Cagla Deniz Bahadir , Benjamin Liechty , David J. Pisapia , Mert R. Sabuncu

Synthetic data generation in histopathology faces unique challenges: preserving tissue heterogeneity, capturing subtle morphological features, and scaling to unannotated datasets. We present a latent diffusion model that generates realistic…

计算机视觉与模式识别 · 计算机科学 2025-10-03 Saghir Alfasly , Wataru Uegami , MD Enamul Hoq , Ghazal Alabtah , H. R. Tizhoosh

Segmenting tumors in histological images is vital for cancer diagnosis. While fully supervised models excel with pixel-level annotations, creating such annotations is labor-intensive and costly. Accurate histopathology image segmentation…

计算机视觉与模式识别 · 计算机科学 2024-07-16 Yinsheng He , Xingyu Li , Roger J. Zemp

In recent years, computational pathology has seen tremendous progress driven by deep learning methods in segmentation and classification tasks aiding prognostic and diagnostic settings. Nuclei segmentation, for instance, is an important…

图像与视频处理 · 电气工程与系统科学 2023-03-22 Aman Shrivastava , P. Thomas Fletcher

Tissue-level semantic segmentation is a vital step in computational pathology. Fully-supervised models have already achieved outstanding performance with dense pixel-level annotations. However, drawing such labels on the giga-pixel whole…

Poor performance of quantitative analysis in histopathological Whole Slide Images (WSI) has been a significant obstacle in clinical practice. Annotating large-scale WSIs manually is a demanding and time-consuming task, unlikely to yield the…

计算机视觉与模式识别 · 计算机科学 2023-08-08 Sarah Cechnicka , James Ball , Hadrien Reynaud , Callum Arthurs , Candice Roufosse , Bernhard Kainz

Diffusion-based generative models have shown promise in synthesizing histopathology images to address data scarcity caused by privacy constraints. Diagnostic text reports provide high-level semantic descriptions, and masks offer…

计算机视觉与模式识别 · 计算机科学 2025-07-01 Mahesh Bhosale , Abdul Wasi , Yuanhao Zhai , Yunjie Tian , Samuel Border , Nan Xi , Pinaki Sarder , Junsong Yuan , David Doermann , Xuan Gong

Immunohistochemistry (IHC) is essential for assessing specific immune biomarkers like Human Epidermal growth-factor Receptor 2 (HER2) in breast cancer. However, the traditional protocols of obtaining IHC stains are resource-intensive,…

图像与视频处理 · 电气工程与系统科学 2026-04-10 Aasim Bin Saleem , Amr Ahmed , Ardhendu Behera , Hafeezullah Amin , Iman Yi Liao , Mahmoud Khattab , Pan Jia Wern , Haslina Makmur

In the field of computational pathology, deep learning algorithms have made significant progress in tasks such as nuclei segmentation and classification. However, the potential of these advanced methods is limited by the lack of available…

计算机视觉与模式识别 · 计算机科学 2024-07-22 Hyun-Jic Oh , Won-Ki Jeong

Scarcity of annotated data, particularly for rare or atypical morphologies, present significant challenges for cell and nuclei segmentation in computational pathology. While manual annotation is labor-intensive and costly, synthetic data…

计算机视觉与模式识别 · 计算机科学 2025-10-21 Dominik Winter , Mai Bui , Monica Azqueta Gavaldon , Nicolas Triltsch , Marco Rosati , Nicolas Brieu

Tissue semantic segmentation is one of the key tasks in computational pathology. To avoid the expensive and laborious acquisition of pixel-level annotations, a wide range of studies attempt to adopt the class activation map (CAM), a…

计算机视觉与模式识别 · 计算机科学 2024-12-31 Zijie Fang , Yifeng Wang , Peizhang Xie , Zhi Wang , Yongbing Zhang

Histopathology can help clinicians make accurate diagnoses, determine disease prognosis, and plan appropriate treatment strategies. As deep learning techniques prove successful in the medical domain, the primary challenges become limited…

计算机视觉与模式识别 · 计算机科学 2024-07-11 Zhe Li , Bernhard Kainz

Medical professionals, especially those in training, often depend on visual reference materials to support an accurate diagnosis and develop pattern recognition skills. However, existing resources may lack the diversity and accessibility…

计算机视觉与模式识别 · 计算机科学 2025-06-03 Kanishk Choudhary
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