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The integration of Large Language Models (LLMs) into the drug discovery and development field marks a significant paradigm shift, offering novel methodologies for understanding disease mechanisms, facilitating drug discovery, and optimizing…

定量方法 · 定量生物学 2024-09-10 Yizhen Zheng , Huan Yee Koh , Maddie Yang , Li Li , Lauren T. May , Geoffrey I. Webb , Shirui Pan , George Church

The rapid development of Artificial Intelligence (AI) has revolutionized numerous fields, with large language models (LLMs) and computer vision (CV) systems driving advancements in natural language understanding and visual processing,…

This paper presents a comprehensive performance evaluation of Large Language Models (LLMs) in solving programming challenges from Leetcode, a widely used platform for algorithm practice and technical interviews. We began by crawling the…

软件工程 · 计算机科学 2025-03-04 Lun Wang , Chuanqi Shi , Shaoshui Du , Yiyi Tao , Yixian Shen , Hang Zheng , Yanxin Shen , Xinyu Qiu

Large language models (LLMs) are increasingly embedded in AI-based tutoring systems. Can they faithfully model novice reasoning and metacognitive judgments? Existing evaluations emphasize problem-solving accuracy, overlooking the fragmented…

计算与语言 · 计算机科学 2026-05-12 Conrad Borchers , Jill-Jênn Vie , Roger Azevedo

Large language models (LLMs) have undergone significant expansion and have been increasingly integrated across various domains. Notably, in the realm of robot task planning, LLMs harness their advanced reasoning and language comprehension…

Large Language Models (LLMs) have achieved remarkable success in source code understanding, yet as software systems grow in scale, computational efficiency has become a critical bottleneck. Currently, these models rely on a text-based…

计算与语言 · 计算机科学 2026-04-29 Yuling Shi , Chaoxiang Xie , Zhensu Sun , Yeheng Chen , Chenxu Zhang , Longfei Yun , Chengcheng Wan , Hongyu Zhang , David Lo , Xiaodong Gu

Large Language Models (LLMs) have demonstrated impressive progress in complex reasoning tasks, largely driven by the Chain-of-Thought (CoT) paradigm, which decomposes difficult problems into intermediate steps. However, CoT reasoning…

符号计算 · 计算机科学 2026-05-26 Rui Wang , Zeming Wei , Yihao Zhang , Xiaokun Luan

Despite rapid advances in Large Language Models and Multimodal Large Language Models (LLMs), numerous challenges related to interpretability, scalability, resource requirements and repeatability remain, related to their application in the…

软件工程 · 计算机科学 2025-07-23 Sohaib Muhammad , Ashwati Vipin , Karan Shetti , Honey Mittal

Robotic path planning problems are often NP-hard, and practical solutions typically rely on approximation algorithms with provable performance guarantees for general cases. While designing such algorithms is challenging, formally proving…

机器人学 · 计算机科学 2026-03-23 Zhengbang Yang , Md. Tasin Tazwar , Minghan Wei , Zhuangdi Zhu

Logical reasoning, i.e., deductively inferring the truth value of a conclusion from a set of premises, is an important task for artificial intelligence with wide potential impacts on science, mathematics, and society. While many…

This paper investigates the capabilities of large language models (LLMs) in formulating and solving decision-making problems using mathematical programming. We first conduct a systematic review and meta-analysis of recent literature to…

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

We introduce SIMCOPILOT, a benchmark that simulates the role of large language models (LLMs) as interactive, "copilot"-style coding assistants. Targeting both completion (finishing incomplete methods or code blocks) and infill tasks…

机器学习 · 计算机科学 2025-05-29 Mingchao Jiang , Abhinav Jain , Sophia Zorek , Chris Jermaine

The field of machine learning (ML) has gained widespread adoption, leading to significant demand for adapting ML to specific scenarios, which is yet expensive and non-trivial. The predominant approaches towards the automation of solving ML…

机器学习 · 计算机科学 2024-02-20 Lei Zhang , Yuge Zhang , Kan Ren , Dongsheng Li , Yuqing Yang

The rapid rise of Large Language Models (LLMs) has changed software development, with tools like Copilot, JetBrains AI Assistant, and others boosting developers' productivity. However, developers now spend more time reviewing code than…

软件工程 · 计算机科学 2024-07-08 Agnia Sergeyuk , Olga Lvova , Sergey Titov , Anastasiia Serova , Farid Bagirov , Timofey Bryksin

Large language models (LLMs) have greatly improved their capability in performing NLP tasks. However, deeper semantic understanding, contextual coherence, and more subtle reasoning are still difficult to obtain. The paper discusses…

计算与语言 · 计算机科学 2025-12-05 Mohanakrishnan Hariharan

With the advent of large language models (LLMs), in both the open source and proprietary domains, attention is turning to how to exploit such artificial intelligence (AI) systems in assisting complex scientific tasks, such as material…

人机交互 · 计算机科学 2024-01-26 Yongtao Liu , Marti Checa , Rama K. Vasudevan

Natural language understanding requires interleaving textual and logical reasoning, yet large language models often fail to perform such reasoning reliably. Existing neurosymbolic systems combine LLMs with solvers but remain limited to…

人工智能 · 计算机科学 2026-02-23 Hyunseok Oh , Sam Stern , Youngki Lee , Matthai Philipose

As software grows in complexity to accommodate diverse features and platforms, software bloating has emerged as a significant challenge, adversely affecting performance and security. However, existing approaches inadequately address the…

软件工程 · 计算机科学 2025-03-13 Bo Lin , Shangwen Wang , Yihao Qin , Liqian Chen , Xiaoguang Mao

The telecommunications and networking domain stands at the precipice of a transformative era, driven by the necessity to manage increasingly complex, hierarchical, multi administrative domains (i.e., several operators on the same path) and…

网络与互联网体系结构 · 计算机科学 2025-06-30 Viswanath Kumarskandpriya , Abdulhalim Dandoush , Abbas Bradai , Ali Belgacem