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In the past decade, there has been a surge in research examining the use of voice and speech analysis as a means of detecting neurodegenerative diseases such as Alzheimer's. Many studies have shown that certain acoustic features can be used…

音频与语音处理 · 电气工程与系统科学 2023-07-20 Vrindha M. K. , Geethu V. , Anurenjan P. R. , Deepak S. , Sreeni K. G.

One of the most prevalent complaints of individuals with mid-stage and advanced Parkinson's disease (PD) is the fluctuating response to their medication (i.e., ON state with maximum benefit from medication and OFF state with no benefit from…

计算机视觉与模式识别 · 计算机科学 2018-09-20 Murtadha D. Hssayeni , Michelle A. Burack , M. D. , Joohi Jimenez-Shahed , M. D. , Behnaz Ghoraani , Ph. D

Orofacial deficits are common in people with Parkinson's disease (PD) and their evolution might represent an important biomarker of disease progression. We are developing an automated system for assessment of orofacial function in PD that…

计算机视觉与模式识别 · 计算机科学 2020-03-19 Diego L. Guarin , Aidan Dempster , Andrea Bandini , Yana Yunusova , Babak Taati

Background: An early diagnosis together with an accurate disease progression monitoring of multiple sclerosis is an important component of successful disease management. Prior studies have established that multiple sclerosis is correlated…

音频与语音处理 · 电气工程与系统科学 2021-09-28 Emil Svoboda , Tomáš Bořil , Jan Rusz , Tereza Tykalová , Dana Horáková , Charles R. G. Guttman , Krastan B. Blagoev , Hiroto Hatabu , Vlad I. Valtchinov

Parkinson disease (PD)'s speech recognition is an effective way for its diagnosis, which has become a hot and difficult research area in recent years. As we know, there are large corpuses (segments) within one subject. However, too large…

声音 · 计算机科学 2021-11-18 Yiwen Wang , Fan Li , Xiaoheng Zhang , Pin Wang , Yongming Li

In this paper, we introduce a novel approach for diagnosis of Parkinson's Disease (PD) based on deep Echo State Networks (ESNs). The identification of PD is performed by analyzing the whole time-series collected from a tablet device during…

机器学习 · 计算机科学 2018-02-20 Claudio Gallicchio , Alessio Micheli , Luca Pedrelli

PD is linked to faster brain aging. Sex is recognized as an important factor in PD, such that males are twice as likely as females to have the disease and have more severe symptoms and a faster progression rate. Despite previous research,…

神经元与认知 · 定量生物学 2023-09-20 Iman Beheshti , Samuel Booth , Ji Hyun Ko

Parkinson's disease (PD) severity diagnosis is crucial for early detecting potential patients and adopting tailored interventions. Diagnosing PD based on facial expression is grounded in PD patients' "masked face" symptom and gains growing…

计算机视觉与模式识别 · 计算机科学 2025-10-22 Yintao Zhou , Wei Huang , Zhengyu Li , Jing Huang , Meng Pang

Early and accurate identification of parkinsonian syndromes (PS) involving presynaptic degeneration from non-degenerative variants such as Scans Without Evidence of Dopaminergic Deficit (SWEDD) and tremor disorders, is important for…

应用统计 · 统计学 2017-03-07 R. Prashanth , Sumantra Dutta Roy , Pravat K. Mandal , Shantanu Ghosh

Speech-language pathologists (SLPs) frequently use vocal exercises in the treatment of patients with speech disorders. Patients receive treatment in a clinical setting and need to practice outside of the clinical setting to generalize…

计算机与社会 · 计算机科学 2016-05-23 Harishchandra Dubey , J. Cody Goldberg , Kunal Mankodiya , Leslie Mahler

Today, data collection has improved in various areas, and the medical domain is no exception. Auscultation, as an important diagnostic technique for physicians, due to the progress and availability of digital stethoscopes, lends itself well…

In recent years, deep learning methods have achieved great success in various fields due to their strong performance in practical applications. In this paper, we present a light-weight neural network for Parkinson's disease diagnostics, in…

At present, the vast majority of human subjects with neurological disease are still diagnosed through in-person assessments and qualitative analysis of patient data. In this paper, we propose to use Topological Data Analysis (TDA) together…

机器学习 · 计算机科学 2020-05-07 Afra Nawar , Farhan Rahman , Narayanan Krishnamurthi , Anirudh Som , Pavan Turaga

Parkinson's disease (PD) is one of the most common neurodegenerative disorder. PD telemonitoring emerges as a novel assessment modality enabling self-administered at-home tests of Unified Parkinson's Disease Rating Scale (UPDRS) scores,…

机器学习 · 计算机科学 2025-10-03 Ziming Tang , Chengbin Hou , Tianyu Zhang , Bangxu Tian , Jinbao Wang , Hairong Lv

Parkinson's Disease (PD) is associated with gait movement disorders, such as bradykinesia, stiffness, tremors and postural instability, caused by progressive dopamine deficiency. Today, some approaches have implemented learning…

计算机视觉与模式识别 · 计算机科学 2024-09-04 Edgar Rangel , Fabio Martinez

Limited accessibility to neurological care leads to underdiagnosed Parkinson's Disease (PD), preventing early intervention. Existing AI-based PD detection methods primarily focus on unimodal analysis of motor or speech tasks, overlooking…

Parkinson's disease is a progressive and slowly developing neurodegenerative disease, characterized by dopaminergic neuron loss in the substantia nigra region of the brain. Despite extensive research by scientists, there is not yet a cure…

定量方法 · 定量生物学 2024-08-31 Pratham Kankariya , Rachita Rode , Kevin Mudaliar , Pranali Hatode

Eye movements can reveal early signs of neurodegeneration, including those associated with Parkinson's Disease (PD). This work investigates the utility of a set of gaze-based features for the automatic screening of PD from different visual…

The USA Food and Drug Administration has accorded increasing importance to patient-reported problems in clinical and research settings. In this paper, we explore one of the largest online datasets comprising 170,141 open-ended self-reported…

计算与语言 · 计算机科学 2023-05-09 Lakshmi Arbatti , Abhishek Hosamath , Vikram Ramanarayanan , Ira Shoulson

In this study, we executed a genomic analysis with the objective of selecting a set of genes (possibly small) that would help in the detection and classification of samples from patients affected by Parkinson Disease. We performed a…

机器学习 · 计算机科学 2016-02-24 Giancarlo Crocetti , Michael Coakley , Phil Dressner , Wanda Kellum , Tamba Lamin