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Recently, a number of drug-therapy, disease, drug, and drug-target networks have been introduced. Here we suggest novel methods for network-based prediction of novel drug targets and for improvement of drug efficiency by analysing the…

分子网络 · 定量生物学 2008-07-31 Zoltan Spiro , Istvan A. Kovacs , Peter Csermely

Socially-aware robotic navigation is essential in environments where humans and robots coexist, ensuring both safety and comfort. However, most existing approaches have been primarily developed for mobile robots, leaving a significant gap…

机器人学 · 计算机科学 2025-06-18 Caio C. G. Ribeiro , Leonardo R. D. Paes , Douglas G. Macharet

Hydrophobically modified magnetic nanoparticles (MNPs) were encapsulated within the membrane of poly(trimethylene carbonate)-b-poly(L-glutamic acid) (PTMC-b-PGA) block copolymer vesicles using a nanoprecipitation process. This formulation…

Molecular communication (MC) is a bio-inspired method of transmitting information using biochemical signals, promising for novel medical, agricultural, and environmental applications at the intersection of bio-, nano-, and communication…

新兴技术 · 计算机科学 2024-08-20 Eren Akyol , Ahmet Baha Ozturk , Iman Mokari Bolhassan , Murat Kuscu

Machine learning shows great potential in virtual screening for drug discovery. Current efforts on accelerating docking-based virtual screening do not consider using existing data of other previously developed targets. To make use of the…

机器学习 · 计算机科学 2021-12-14 Zijing Liu , Xianbin Ye , Xiaomin Fang , Fan Wang , Hua Wu , Haifeng Wang

Drug recommendation (DR) systems aim to support healthcare professionals in selecting appropriate medications based on patients' medical conditions. State-of-the-art approaches utilize deep learning techniques for improving DR, but fall…

信息检索 · 计算机科学 2025-11-03 Yu Lin , Zhen Jia , Philipp Christmann , Xu Zhang , Shengdong Du , Tianrui Li

This paper addresses the challenges of distributed formation control in multiple mobile robots, introducing a novel approach that enhances real-world practicability. We first introduce a distributed estimator using a variable structure and…

机器人学 · 计算机科学 2024-03-26 Zhe Xu , Tao Yan , Simon X. Yang , S. Andrew Gadsden , Mohammad Biglarbegian

Microfluidic systems, when combined with microrobots, offer enhanced precision in chemical synthesis by precisely controlling reaction conditions. These systems, when integrated with analytical tools, allow for real-time monitoring and are…

The paper proposes a feed-forward control strategy for mobile robot control that accounts for a non-linear model of the vehicle with interaction between inputs and outputs. It is possible to include specific model uncertainties in the…

机器人学 · 计算机科学 2015-12-11 Ioan Dumitrache , Monica Dragoicea

Consider an assistive system that guides visually impaired users through speech and haptic feedback to their destination. Existing robotic and ubiquitous navigation technologies (e.g., portable, ground, or wearable systems) often operate in…

机器学习 · 计算机科学 2018-10-09 Eshed Ohn-Bar , Kris Kitani , Chieko Asakawa

Recent applications of deep learning to navigation have generated end-to-end navigation solutions whereby visual sensor input is mapped to control signals or to motion primitives. The resulting visual navigation strategies work very well at…

机器人学 · 计算机科学 2018-01-17 Justin S. Smith , Jin-Ha Hwang , Fu-Jen Chu , Patricio A. Vela

This study examines the problem of hopping robot navigation planning to achieve simultaneous goal-directed and environment exploration tasks. We consider a scenario in which the robot has mandatory goal-directed tasks defined using Linear…

机器人学 · 计算机科学 2024-07-10 Jesse Jiang , Samuel Coogan , Ye Zhao

Magnetic soft robots embedded with hard magnetic particles enable untethered actuation via external magnetic fields, offering remote, rapid, and precise control, which is highly promising for biomedical applications. However, designing such…

机器人学 · 计算机科学 2025-07-15 Liwei Wang

Cancer remains a leading cause of death worldwide, necessitating personalized treatment approaches to improve outcomes. Theranostics, combining molecular-level imaging with targeted therapy, offers potential for precision oncology but…

计算工程、金融与科学 · 计算机科学 2025-05-16 Binesh Sadanandan , Vahid Behzadan

Enhancing robot navigation efficiency is a crucial objective in modern robotics. Robots relying on external navigation systems are often susceptible to electromagnetic interference (EMI) and encounter environmental disturbances, resulting…

机器人学 · 计算机科学 2024-04-03 Saleem Alzoubi , Mahdi H. Miraz

Neuromodulation techniques have emerged as promising approaches for treating a wide range of neurological disorders, precisely delivering electrical stimulation to modulate abnormal neuronal activity. While leveraging the unique…

Drug delivery to the brain is limited by the blood-brain barrier (BBB). We developed a capacitive micromachined ultrasonic transducer (CMUT)-based transcranial focused ultrasound system capable of both delivering therapy via BBB opening and…

We consider a single kinematically controlled robot with a bounded control range. The robot travels in a two-dimensional region supporting an unknown unsteady scalar field. A single sensor provides the field value at the current location of…

最优化与控制 · 数学 2015-02-10 Alexey S. Matveev , Michael C. Hoy , Andrey V. Savkin

This paper studies the multi-robot reliable navigation problem in uncertain topological networks, which aims at maximizing the robot team's on-time arrival probabilities in the face of road network uncertainties. The uncertainty in these…

Autonomous wheeled-legged robots have the potential to transform logistics systems, improving operational efficiency and adaptability in urban environments. Navigating urban environments, however, poses unique challenges for robots,…

机器人学 · 计算机科学 2024-05-06 Joonho Lee , Marko Bjelonic , Alexander Reske , Lorenz Wellhausen , Takahiro Miki , Marco Hutter