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相关论文: Multiplex Nodal Modularity: A novel network metric…

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Many complex networks have an underlying modular structure, i.e., structural subunits (communities or clusters) characterized by highly interconnected nodes. The modularity $Q$ has been introduced as a measure to assess the quality of…

无序系统与神经网络 · 物理学 2009-11-11 Stefanie Muff , Francesco Rao , Amedeo Caflisch

Analysis and quantification of brain structural changes, using Magnetic resonance imaging (MRI), are increasingly used to define novel biomarkers of brain pathologies, such as Alzheimer's disease (AD). Network-based models of the brain have…

Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Amnestic mild cognitive impairment (MCI) is a common first symptom before the conversion to clinical impairment where the individual becomes unable to perform activities…

计算机视觉与模式识别 · 计算机科学 2017-10-16 Donghuan Lu , Karteek Popuri , Weiguang Ding , Rakesh Balachandar , Mirza Faisal Beg

Community-aware centrality is an emerging research area in network science concerned with the importance of nodes in relation to community structure. Measures are a function of a network's structure and a given partition. Previous…

社会与信息网络 · 计算机科学 2021-01-08 Thomas Magelinski , Mihovil Bartulovic , Kathleen M. Carley

\textbf{Objective:} Alzheimer's disease (AD) is the most prevalent form of dementia worldwide, encompassing a prodromal stage known as Mild Cognitive Impairment (MCI), where patients may either progress to AD or remain stable. The objective…

Brain networks from functional MRI have advanced our understanding of cortical activity and its disruption in neurodegenerative disorders. Recent work has increasingly focused on dynamic (time-varying) brain networks that capture both…

神经元与认知 · 定量生物学 2026-04-14 Nicolas Rubido , Venia Batziou , Marwan Fuad , Vesna Vuksanovic

The modular structure of brain networks supports specialized information processing, complex dynamics, and cost-efficient spatial embedding. Inter-individual variation in modular structure has been linked to differences in performance,…

Alzheimer's disease (AD) causes alterations of brain network structure and function. The latter consists of connectivity changes between oscillatory processes at different frequency channels. We proposed a multi-layer network approach to…

We investigate the use of modularity as a quantifier of whole-brain functional networks. Brain networks are constructed from functional magnetic resonance imaging while subjects listened to auditory pieces that varied in emotivity and…

神经元与认知 · 定量生物学 2020-09-23 Melia E. Bonomo , Christof Karmonik , Anthony K. Brandt , J. Todd Frazier

Alzheimer's disease (AD) progression follows a complex continuum from normal cognition (NC) through mild cognitive impairment (MCI) to dementia, yet most deep learning approaches oversimplify this into discrete classification tasks. This…

图像与视频处理 · 电气工程与系统科学 2025-08-05 Yufeng Jiang , Hexiao Ding , Hongzhao Chen , Jing Lan , Xinzhi Teng , Gerald W. Y. Cheng , Zongxi Li , Haoran Xie , Jung Sun Yoo , Jing Cai

Modularity plays an important role in brain networks' architecture and influences its dynamics and the ability to integrate and segregate different modules of cerebral regions. Alterations in community structure are associated with several…

神经元与认知 · 定量生物学 2018-05-14 M. Cinelli , I. Echegoyen , M. Oliveira , S. Orellana , T. Gili

The early detection of Alzheimer's Disease is imperative to ensure early treatment and improve patient outcomes. There has consequently been extenstive research into detecting AD and its intermediate phase, mild cognitive impairment (MCI).…

图像与视频处理 · 电气工程与系统科学 2024-01-17 Jamie Vo , Naeha Sharif , Ghulam Mubashar Hassan

Revealing a community structure in a network or dataset is a central problem arising in many scientific areas. The modularity function $Q$ is an established measure quantifying the quality of a community, being identified as a set of nodes…

社会与信息网络 · 计算机科学 2018-09-13 Francesco Tudisco , Pedro Mercado , Matthias Hein

Alzheimer's disease (AD) is associated with local (e.g. brain tissue atrophy) and global brain changes (loss of cerebral connectivity), which can be detected by high-resolution structural magnetic resonance imaging. Conventionally, these…

机器学习 · 计算机科学 2021-05-11 Sarah C. Brüningk , Felix Hensel , Catherine R. Jutzeler , Bastian Rieck

Brain network topology, derived from functional magnetic resonance imaging (fMRI), holds promise for improving Alzheimer's disease (AD) diagnosis. Current methods primarily focus on lower-order topological features, often overlooking the…

几何拓扑 · 数学 2025-09-19 Dengyi Zhao , Shanyong Li , Yunping Wang , Chenfei Wang , Zhiheng Zhou , Guiying Yan , Xingqin Qi

Recent work in cognitive neuroscience has focused on analyzing the brain as a network, rather than as a collection of independent regions. Prior studies taking this approach have found that individual differences in the degree of modularity…

神经元与认知 · 定量生物学 2017-11-28 Qiuhai Yue , Randi Martin , Simon Fischer-Baum , Aurora I. Ramos-Nuñez , Fengdan Ye , Michael W. Deem

Neural Module Networks (NMNs) aim at Visual Question Answering (VQA) via composition of modules that tackle a sub-task. NMNs are a promising strategy to achieve systematic generalization, i.e., overcoming biasing factors in the training…

机器学习 · 计算机科学 2022-01-19 Vanessa D'Amario , Tomotake Sasaki , Xavier Boix

Normative modelling is an emerging method for understanding the underlying heterogeneity within brain disorders like Alzheimer Disease (AD) by quantifying how each patient deviates from the expected normative pattern that has been learned…

图像与视频处理 · 电气工程与系统科学 2026-02-06 Sayantan Kumar , Philip Payne , Aristeidis Sotiras

The assessment of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) associated with brain changes remains a challenging task. Recent studies have demonstrated that combination of multi-modality imaging techniques can better…

机器学习 · 计算机科学 2022-09-26 Jun Yu , Zhaoming Kong , Liang Zhan , Li Shen , Lifang He

Efficient complex systems have a modular structure, but modularity does not guarantee robustness, because efficiency also requires an ingenious interplay of the interacting modular components. The human brain is the elemental paradigm of an…

神经元与认知 · 定量生物学 2022-06-08 Flaviano Morone , Kevin Roth , Byungjoon Min , H. Eugene Stanley , Hernán A. Makse
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