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Pretraining on large-scale, in-domain datasets grants histopathology foundation models (FM) the ability to learn task-agnostic data representations, enhancing transfer learning on downstream tasks. In computational pathology, automated…

计算机视觉与模式识别 · 计算机科学 2025-07-22 Pablo Meseguer , Rocío del Amor , Valery Naranjo

Breast cancer is a serious disease that inflicts millions of people each year, and the number of cases is increasing. Early detection is the best way to reduce the impact of the disease. Researchers have developed many techniques to detect…

人工智能 · 计算机科学 2023-11-23 Mosab S. M. Farea , zhe chen

Deep-learning models based on whole-slide digital pathology images (WSIs) become increasingly popular for predicting molecular biomarkers. Instance-based models has been the mainstream strategy for predicting genetic alterations using WSIs…

定量方法 · 定量生物学 2022-06-02 Bangwei Guo , Xingyu Li , Miaomiao Yang , Hong Zhang , Xu Steven Xu

Visual microscopic study of diseased tissue by pathologists has been the cornerstone for cancer diagnosis and prognostication for more than a century. Recently, deep learning methods have made significant advances in the analysis and…

图像与视频处理 · 电气工程与系统科学 2022-09-30 Puria Azadi Moghadam , Sanne Van Dalen , Karina C. Martin , Jochen Lennerz , Stephen Yip , Hossein Farahani , Ali Bashashati

Malignant mesothelioma is classified into three histological subtypes, Epithelioid, Sarcomatoid, and Biphasic according to the relative proportions of epithelioid and sarcomatoid tumor cells present. Biphasic tumors display significant…

Empirical evaluation of breast tissue biopsies for mitotic nuclei detection is considered an important prognostic biomarker in tumor grading and cancer progression. However, automated mitotic nuclei detection poses several challenges…

计算机视觉与模式识别 · 计算机科学 2020-03-20 Anabia Sohail , Muhammad Ahsan Mukhtar , Asifullah Khan , Muhammad Mohsin Zafar , Aneela Zameer , Saranjam Khan

Breast cancer is one of the most common cancers affecting women worldwide. They include a group of malignant neoplasms with a variety of biological, clinical, and histopathological characteristics. There are more than 35 different…

图像与视频处理 · 电气工程与系统科学 2023-08-23 Abubakr Shafique , Ricardo Gonzalez , Liron Pantanowitz , Puay Hoon Tan , Alberto Machado , Ian A Cree , Hamid R. Tizhoosh

Recognizing atypical mitotic figures in histopathology images allows physicians to correctly assess tumor aggressiveness. Although machine learning models could be exploited for automatically performing such a task, under domain shift these…

图像与视频处理 · 电气工程与系统科学 2025-09-10 Gennaro Percannella , Mattia Sarno , Francesco Tortorella , Mario Vento

Breast cancer is becoming pervasive with each passing day. Hence, its early detection is a big step in saving the life of any patient. Mammography is a common tool in breast cancer diagnosis. The most important step here is classification…

计算机视觉与模式识别 · 计算机科学 2018-01-04 Aditya A. Shastri , Deepti Tamrakar , Kapil Ahuja

As much as data science is playing a pivotal role everywhere, healthcare also finds it prominent application. Breast Cancer is the top rated type of cancer amongst women; which took away 627,000 lives alone. This high mortality rate due to…

机器学习 · 计算机科学 2019-02-26 Vivek Kumar , Brojo Kishore Mishra , Manuel Mazzara , Dang N. H. Thanh , Abhishek Verma

Mitosis nuclei count is one of the important indicators for the pathological diagnosis of breast cancer. The manual annotation needs experienced pathologists, which is very time-consuming and inefficient. With the development of deep…

计算机视觉与模式识别 · 计算机科学 2022-12-29 Huadeng Wang , Zhipeng Liu , Rushi Lan , Zhenbing Liu , Xiaonan Luo , Xipeng Pan , Bingbing Li

A Pathology report is arguably one of the most important documents in medicine containing interpretive information about the visual findings from the patient's biopsy sample. Each pathology report has a retention period of up to 20 years…

计算与语言 · 计算机科学 2019-03-19 Shivam Kalra , Larry Li , Hamid R. Tizhoosh

Notorious for its 70-80% recurrence rate, Non-muscle-invasive Bladder Cancer (NMIBC) imposes a significant human burden and is one of the costliest cancers to manage. Current tools for predicting NMIBC recurrence rely on scoring systems…

机器学习 · 计算机科学 2024-12-23 Saram Abbas , Rishad Shafik , Naeem Soomro , Rakesh Heer , Kabita Adhikari

Reliable diagnosis of brain tumors remains challenging due to low clinical incidence rates of such cases. However, this low rate is neglected in most of proposed methods. We propose a clinically inspired framework for anomaly-resilient…

图像与视频处理 · 电气工程与系统科学 2025-07-02 Seyed Mohammad Hossein Hashemi , Leila Safari , Mohsen Hooshmand , Amirhossein Dadashzadeh Taromi

Histopathological prognostication of neoplasia including most tumor grading systems are based upon a number of criteria. Probably the most important is the number of mitotic figures which are most commonly determined as the mitotic count…

计算机视觉与模式识别 · 计算机科学 2020-01-06 Marc Aubreville , Christof A. Bertram , Robert Klopfleisch , Andreas Maier

Microscopic histology image analysis is a cornerstone in early detection of breast cancer. However these images are very large and manual analysis is error prone and very time consuming. Thus automating this process is in high demand. We…

计算机视觉与模式识别 · 计算机科学 2018-10-23 Ismaël Koné , Lahsen Boulmane

Gastric cancer ranks as the fifth most common and fourth most lethal cancer globally, with a dismal 5-year survival rate of approximately 20%. Despite extensive research on its pathobiology, the prognostic predictability remains inadequate,…

图像与视频处理 · 电气工程与系统科学 2025-03-24 Marco Usai , Andrea Loddo , Alessandra Perniciano , Maurizio Atzori , Cecilia Di Ruberto

This work addresses how to efficiently classify challenging histopathology images, such as gigapixel whole-slide images for cancer diagnostics with image-level annotation. We use images with annotated tumor regions to identify a set of…

图像与视频处理 · 电气工程与系统科学 2024-09-24 Mohammad Iqbal Nouyed , Mary-Anne Hartley , Gianfranco Doretto , Donald A. Adjeroh

Developing and validating artificial intelligence models in medical imaging requires datasets that are large, granular, and diverse. To date, the majority of publicly available breast imaging datasets lack in one or more of these areas.…