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Prediction models need reliable predictive performance as they inform clinical decisions, aiding in diagnosis, prognosis, and treatment planning. The predictive performance of these models is typically assessed through discrimination and…

统计方法学 · 统计学 2025-04-25 Wouter A. C. van Amsterdam

Individuals often make different decisions when faced with the same context, due to personal preferences and background. For instance, judges may vary in their leniency towards certain drug-related offenses, and doctors may vary in their…

机器学习 · 计算机科学 2021-10-28 Justin Lim , Christina X Ji , Michael Oberst , Saul Blecker , Leora Horwitz , David Sontag

Predictive or treatment selection biomarkers are usually evaluated in a subgroup or regression analysis with focus on the treatment-by-marker interaction. Under a potential outcome framework (Huang, Gilbert and Janes [Biometrics 68 (2012)…

应用统计 · 统计学 2015-02-04 Zhiwei Zhang , Lei Nie , Guoxing Soon , Aiyi Liu

Prior to clinical applications, it is critical that risk prediction models are evaluated in independent studies that did not contribute to model development. While prospective cohort studies provide a natural setting for model validation,…

统计方法学 · 统计学 2017-10-13 Parichoy Pal Choudhury , Anil K. Chaturvedi , Nilanjan Chatterjee

The discovery of discriminatory bias in human or automated decision making is a task of increasing importance and difficulty, exacerbated by the pervasive use of machine learning and data mining. Currently, discrimination discovery largely…

计算机与社会 · 计算机科学 2019-11-05 Bilal Qureshi , Faisal Kamiran , Asim Karim , Salvatore Ruggieri , Dino Pedreschi

A data science task can be deemed as making sense of the data or testing a hypothesis about it. The conclusions inferred from data can greatly guide us to make informative decisions. Big data has enabled us to carry out countless prediction…

机器学习 · 计算机科学 2022-01-12 Wenhao Zhang , Ramin Ramezani , Arash Naeim

Prediction models are used amongst others to inform medical decisions on interventions. Typically, individuals with high risks of adverse outcomes are advised to undergo an intervention while those at low risk are advised to refrain from…

Predictions about people, such as their expected educational achievement or their credit risk, can be performative and shape the outcome that they aim to predict. Understanding the causal effect of these predictions on the eventual outcomes…

机器学习 · 统计学 2022-10-19 Celestine Mendler-Dünner , Frances Ding , Yixin Wang

The problem of model selection is inevitable in an increasingly large number of applications involving partial theoretical knowledge and vast amounts of information, like in medicine, biology or economics. The associated techniques are…

统计方法学 · 统计学 2015-11-17 Stephane Guerrier , Maria-Pia Victoria-Feser

Science can be seen as a sequential process where each new study augments evidence to the existing knowledge. To have the best prospects to make an impact in this process, a new study should be designed optimally taking into account the…

统计方法学 · 统计学 2017-01-03 Juha Karvanen , Mikko J. Sillanpää

In this paper we study approaches for dealing with treatment when developing a clinical prediction model. Analogous to the estimand framework recently proposed by the European Medicines Agency for clinical trials, we propose a…

In studies of discrimination, researchers often seek to estimate a causal effect of race or gender on outcomes. For example, in the criminal justice context, one might ask whether arrested individuals would have been subsequently charged or…

统计方法学 · 统计学 2022-04-06 Johann Gaebler , William Cai , Guillaume Basse , Ravi Shroff , Sharad Goel , Jennifer Hill

Causal inference is capable of estimating the treatment effect (i.e., the causal effect of treatment on the outcome) to benefit the decision making in various domains. One fundamental challenge in this research is that the treatment…

机器学习 · 计算机科学 2021-12-28 Qian Li , Zhichao Wang , Shaowu Liu , Gang Li , Guandong Xu

What is the difference of a prediction that is made with a causal model and a non-causal model? Suppose we intervene on the predictor variables or change the whole environment. The predictions from a causal model will in general work as…

统计方法学 · 统计学 2024-04-27 Jonas Peters , Peter Bühlmann , Nicolai Meinshausen

Causal inference is best understood using potential outcomes. This use is particularly important in more complex settings, that is, observational studies or randomized experiments with complications such as noncompliance. The topic of this…

统计理论 · 数学 2007-06-13 Donald B. Rubin

Controversy about the significance of underdetermination of theories persists in the philosophy and conduct of science. The issue has practical import when research is used to inform decision making, because scientific uncertainty yields…

计量经济学 · 经济学 2026-04-09 Charles F. Manski

A predictive model makes outcome predictions based on some given features, i.e., it estimates the conditional probability of the outcome given a feature vector. In general, a predictive model cannot estimate the causal effect of a feature…

机器学习 · 计算机科学 2023-04-11 Jiuyong Li , Lin Liu , Ziqi Xu , Ha Xuan Tran , Thuc Duy Le , Jixue Liu

Causal inference is a critical research topic across many domains, such as statistics, computer science, education, public policy and economics, for decades. Nowadays, estimating causal effect from observational data has become an appealing…

统计方法学 · 统计学 2020-02-10 Liuyi Yao , Zhixuan Chu , Sheng Li , Yaliang Li , Jing Gao , Aidong Zhang

Propensity scores are often used for stratification of treatment and control groups of subjects in observational data to remove confounding bias when estimating of causal effect of the treatment on an outcome in so-called potential outcome…

统计理论 · 数学 2018-04-24 Priyantha Wijayatunga

A probabilistic expert system emulates the decision-making ability of a human expert through a directional graphical model. The first step in building such systems is to understand data generation mechanism. To this end, one may try to…

统计方法学 · 统计学 2021-09-29 Vahid Partovi Nia , Xinlin Li , Masoud Asgharian , Shoubo Hu , Zhitang Chen , Yanhui Geng
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