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The identification of predictive biomarkers from a large scale of covariates for subgroup analysis has attracted fundamental attention in medical research. In this article, we propose a generalized penalized regression method with a novel…

统计方法学 · 统计学 2019-04-29 Chong Ma , Wenxuan Deng , Shuangge Ma , Ray Liu , Kevin Galinsky

Here we propose a novel searching scheme for a tuning parameter in high-dimensional penalized regression methods to address variable selection and modeling when sample sizes are limited compared to the data dimensions. Our method is…

定量方法 · 定量生物学 2020-02-11 Tao Jiang , Stephanie J. London , Mi Kyeong Lee , Josyf C. Mychaleckyj , Alison A. Motsinger-Reif

This paper presents an improved implicit sampling method for hierarchical Bayesian inverse problems. A widely used approach for sampling posterior distribution is based on Markov chain Monte Carlo (MCMC). However, the samples generated by…

数值分析 · 数学 2018-11-27 Xiaoyan Song , Lijian Jiang , Guanghui Zheng

The expectation-maximization (EM) algorithm and its variants are widely used in statistics. In high-dimensional mixture linear regression, the model is assumed to be a finite mixture of linear regression and the number of predictors is much…

统计理论 · 数学 2023-07-24 Ning Wang , Xin Zhang , Qing Mai

Gaussian Mixture models (GMMs) are a powerful tool for clustering, classification and density estimation when clustering structures are embedded in the data. The presence of missing values can largely impact the GMMs estimation process,…

机器学习 · 统计学 2020-06-05 Alessio Serafini , Thomas Brendan Murphy , Luca Scrucca

This article investigates uncertainty quantification of the generalized linear lasso~(GLL), a popular variable selection method in high-dimensional regression settings. In many fields of study, researchers use data-driven methods to select…

统计理论 · 数学 2023-07-11 Quentin Duchemin , Yohann de Castro

Gaussian mixture models are widely used to study clustering problems. These model-based clustering methods require an accurate estimation of the unknown data density by Gaussian mixtures. In Maugis and Michel (2009), a penalized maximum…

统计理论 · 数学 2015-03-19 Maugis Cathy , Michel Bertrand

As an effective nonparametric method, empirical likelihood (EL) is appealing in combining estimating equations flexibly and adaptively for incorporating data information. To select important variables and estimating equations in the sparse…

统计方法学 · 统计学 2021-07-02 Jiaqi Li , Liya Fu

This work performs a non-asymptotic analysis of the generalized Lasso under the assumption of sub-exponential data. Our main results continue recent research on the benchmark case of (sub-)Gaussian sample distributions and thereby explore…

统计理论 · 数学 2023-01-18 Martin Genzel , Christian Kipp

Gaussian mixture models (GMM) are the most widely used statistical model for the $k$-means clustering problem and form a popular framework for clustering in machine learning and data analysis. In this paper, we propose a natural semi-random…

数据结构与算法 · 计算机科学 2017-11-27 Pranjal Awasthi , Aravindan Vijayaraghavan

Several strategies have been developed recently to ensure valid inference after model selection; some of these are easy to compute, while others fare better in terms of inferential power. In this paper, we consider a selective inference…

统计方法学 · 统计学 2022-07-13 Snigdha Panigrahi , Jonathan Taylor

High-dimensional data pose challenges in statistical learning and modeling. Sometimes the predictors can be naturally grouped where pursuing the between-group sparsity is desired. Collinearity may occur in real-world high-dimensional…

机器学习 · 统计学 2011-11-11 Yiyuan She

Extending generalized estimating equations (GEE) to ordinal response data requires a conversion of the ordinal response to a vector of binary category indicators. That leads to a rather complicated association structure, and the…

统计方法学 · 统计学 2017-05-23 Aristidis K. Nikoloulopoulos

Accurate statistical inference in logistic regression models remains a critical challenge when the ratio between the number of parameters and sample size is not negligible. This is because approximations based on either classical asymptotic…

统计方法学 · 统计学 2022-08-19 Qian Zhao , Emmanuel J. Candes

We consider the challenges that arise when fitting complex ecological models to 'large' data sets. In particular, we focus on random effect models which are commonly used to describe individual heterogeneity, often present in ecological…

统计方法学 · 统计学 2022-05-17 Ruth King , Blanca Sarzo , Víctor Elvira

We propose an L1-penalized algorithm for fitting high-dimensional generalized linear mixed models. Generalized linear mixed models (GLMMs) can be viewed as an extension of generalized linear models for clustered observations. This…

统计计算 · 统计学 2014-06-03 Jürg Schelldorfer , Lukas Meier , Peter Bühlmann

Clustered and longitudinal data are pervasive in scientific studies, from prenatal health programs to clinical trials and public health surveillance. Such data often involve non-Gaussian responses--including binary, categorical, and count…

统计方法学 · 统计学 2025-09-19 Yibo Wang , Chenlei Leng , Cheng Yong Tang

We propose a method for estimating coefficients in multivariate regression when there is a clustering structure to the response variables. The proposed method includes a fusion penalty, to shrink the difference in fitted values from…

机器学习 · 统计学 2018-03-28 Bradley S. Price , Ben Sherwood

In observational studies, accurately characterizing variance is critical for sample size determination, yet unaccounted-for variability from propensity score estimation and the resulting weights limit the accuracy of standard variance…

统计方法学 · 统计学 2026-04-24 Taekwon Hong , Daeyoung Lim , Woojung Bae , Yong Ma

We study the problem of evaluating the excess risk of large-scale empirical risk minimization under the square loss. Leveraging the idea of wild refitting and resampling, we assume only black-box access to the training algorithm and develop…

机器学习 · 计算机科学 2026-04-03 Haichen Hu , David Simchi-Levi
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