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It has become increasingly popular to study the brain as a network due to the realization that functionality cannot be explained exclusively by independent activation of specialized regions. Instead, across a large spectrum of behaviors,…

神经元与认知 · 定量生物学 2014-07-22 Petko Bogdanov , Nazli Dereli , Danielle S. Bassett , Scott T. Grafton , Ambuj K. Singh

Brain function relies on a precisely coordinated and dynamic balance between the functional integration and segregation of distinct neural systems. Characterizing the way in which neural systems reconfigure their interactions to give rise…

神经元与认知 · 定量生物学 2021-01-28 Lingbin Bian , Tiangang Cui , B. T. Thomas Yeo , Alex Fornito , Adeel Razi , Jonathan Keith

Neuromorphic computing targets energy-efficient event-driven information processing by placing artificial spiking-neurons at its core. Artificial neuron devices and circuits have multiple operating modes and produce region-dependent…

应用物理 · 物理学 2026-01-06 Zhiwei Li , Shi-Li Zhang , Chenyu Wen

The human brain is a complex network comprised of functionally and anatomically interconnected brain regions. A growing number of studies have suggested that empirical estimates of brain networks may be useful for discovery of biomarkers of…

神经元与认知 · 定量生物学 2022-11-15 Andrew Hannum , Mario A. Lopez , Saúl A. Blanco , Richard F. Betzel

Activity in the human brain moves between diverse functional states to meet the demands of our dynamic environment, but fundamental principles guiding these transitions remain poorly understood. Here, we capitalize on recent advances in…

A central challenge in the computational modeling of neural dynamics is the trade-off between accuracy and simplicity. At the level of individual neurons, nonlinear dynamics are both experimentally established and essential for neuronal…

This paper presents an investigation of the dynamics of two coupled non-identical FitzHugh-Nagumo neurons with quadratic term and delayed synaptic connection. We consider coupling strength and time delay as bifurcation parameters, and try…

混沌动力学 · 物理学 2016-02-29 Niloofar Farajzadeh Tehrani , MohammadReza Razvan

Classification of whole-brain functional connectivity MRI data with convolutional neural networks (CNNs) has shown promise, but the complexity of these models impedes understanding of which aspects of brain activity contribute to…

神经元与认知 · 定量生物学 2020-05-28 Matthew Leming , John Suckling

Differential equation-based physiological models of sleep-wake networks describe sleep-wake regulation by simulating the activity of wake- and sleep-promoting neuronal populations and the modulation of these populations by homeostatic and…

动力系统 · 数学 2021-11-16 Christina Athanasouli , Sofia H. Piltz , Cecilia Diniz Behn , Victoria Booth

Brain disorders in the early and late life of humans potentially share pathological alterations in brain functions. However, the key evidence from neuroimaging data for pathological commonness remains unrevealed. To explore this hypothesis,…

人工智能 · 计算机科学 2023-02-24 Mianxin Liu , Jingyang Zhang , Yao Wang , Yan Zhou , Fang Xie , Qihao Guo , Feng Shi , Han Zhang , Qian Wang , Dinggang Shen

Decoding brain functional states underlying different cognitive processes using multivariate pattern recognition techniques has attracted increasing interests in brain imaging studies. Promising performance has been achieved using brain…

计算机视觉与模式识别 · 计算机科学 2018-09-18 Hongming Li , Yong Fan

Bifurcation theory is a powerful tool for studying how the dynamics of a neural network model depends on its underlying neurophysiological parameters. However, bifurcation theory has been developed mostly for smooth dynamical systems and…

神经元与认知 · 定量生物学 2019-01-16 Diego Fasoli , Stefano Panzeri

Deep neural network (DNN) models have demonstrated impressive performance in various domains, yet their application in cognitive neuroscience is limited due to their lack of interpretability. In this study we employ two structurally…

信号处理 · 电气工程与系统科学 2024-09-04 Murat Kucukosmanoglu , Javier O. Garcia , Justin Brooks , Kanika Bansal

Brain Functional Networks (BFNs), graph theoretical models of brain activity data, provide a systems perspective of complex functional connectivity within the brain. Neurological disorders are known to have basis in abnormal functional…

定量方法 · 定量生物学 2016-08-30 Megha Singh , Rahul Badhwar , Ganesh Bagler

Mean field models (MFMs) of cortical tissue incorporate salient features of neural masses to model activity at the population level. One of the common aspects of MFM descriptions is the presence of a high dimensional parameter space…

动力系统 · 数学 2015-05-19 Federico Frascoli , Lennaert van Veen , Ingo Bojak , David T J Liley

Explaining individual differences in cognitive abilities requires both identifying brain parameters that vary across individuals and understanding how brain networks are recruited for specific tasks. Typically, task performance relies on…

神经元与认知 · 定量生物学 2026-05-05 Sida Chen , Siqi Yang , Zhao Chang , Taro Toyoizumi , Werner Sommer , Lianchun Yu , Qian-Yuan Tang , Changsong Zhou

In recent years,the application of deep learning in task functional Magnetic Resonance Imaging (tfMRI) decoding has led to significant advancements. However,most studies remain constrained by assumption of temporal stationarity in neural…

机器学习 · 计算机科学 2025-03-05 Yueyang Wu , Sinan Yang , Yanming Wang , Jiajie He , Muhammad Mohsin Pathan , Bensheng Qiu , Xiaoxiao Wang

Data-driven graph learning models a network by determining the strength of connections between its nodes. The data refers to a graph signal which associates a value with each graph node. Existing graph learning methods either use simplified…

机器学习 · 计算机科学 2020-11-05 Nafiseh Ghoroghchian , David M. Groppe , Roman Genov , Taufik A. Valiante , Stark C. Draper

The development of diagnostic models is gaining traction in the field of psychiatric disorders. Recently, machine learning classifiers based on resting-state functional magnetic resonance imaging (rs-fMRI) have been developed to identify…

机器学习 · 计算机科学 2025-10-06 Tianzheng Hu , Qiang Li , Shu Liu , Vince D. Calhoun , Guido van Wingen , Shujian Yu

Mounting experimental evidence suggests that brain-state-specific neural mechanisms, supported by connectomic architectures, play a crucial role in integrating past and contextual knowledge with the current, incoming flow of evidence (e.g.,…

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