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We outline the approach being developed in the neuGRID project to use provenance management techniques for the purposes of capturing and preserving the provenance data that emerges in the specification and execution of workflows in…

Testing is an essential tool to assure software, especially so in safety-critical applications. To quantify how thoroughly a software item has been tested, a test coverage metric is required. Maybe the strictest such metric known in the…

软件工程 · 计算机科学 2025-11-25 Wanja Zaeske , Pietro Albini , Florian Gilcher , Umut Durak

Building models that comply with the invariances inherent to different domains, such as invariance under translation or rotation, is a key aspect of applying machine learning to real world problems like molecular property prediction,…

机器学习 · 计算机科学 2023-01-04 Jan Schuchardt , Stephan Günnemann

Deep learning models benefit from training with a large dataset (labeled or unlabeled). Following this motivation, we present an approach to learn a deep learning model for the automatic segmentation of Organs at Risk (OARs) in cervical…

图像与视频处理 · 电气工程与系统科学 2023-02-22 Monika Grewal , Dustin van Weersel , Henrike Westerveld , Peter A. N. Bosman , Tanja Alderliesten

Melanoma is the deadliest form of skin cancer. Computer systems can assist in melanoma detection, but are not widespread in clinical practice. In 2016, an open challenge in classification of dermoscopic images of skin lesions was announced.…

Cardiotoxicity related to cancer therapies has become a serious issue, diminishing cancer treatment outcomes and quality of life. Early detection of cancer patients at risk for cardiotoxicity before cardiotoxic treatments and providing…

定量方法 · 定量生物学 2020-05-21 Xi Yang , Yan Gong , Nida Waheed , Keith March , Jiang Bian , William R. Hogan , Yonghui Wu

Rigorous testing of machine learning models is necessary for trustworthy deployments. We present a novel black-box approach for generating test-suites for robust testing of deep neural networks (DNNs). Most existing methods create test…

机器学习 · 计算机科学 2024-08-14 Aishwarya Gupta , Indranil Saha , Piyush Rai

This research paper outlines the development and implementation of a novel Clinical Decision Support System (CDSS) that integrates AI predictive modeling with medical knowledge bases. It utilizes the quantifiable information elements in lab…

Early detection of breast cancer is a powerful tool towards decreasing its socioeconomic burden. Although, artificial intelligence (AI) methods have shown remarkable results towards this goal, their "black box" nature hinders their wide…

机器学习 · 计算机科学 2022-02-07 Panagiota Karatza , Kalliopi V. Dalakleidi , Maria Athanasiou , Konstantina S. Nikita

Artificial Intelligence is providing astonishing results, with medicine being one of its favourite playgrounds. In a few decades, computers may be capable of formulating diagnoses and choosing the correct treatment, while robots may perform…

The behaviour of gene regulatory networks (GRNs) is typically analysed using simulation-based statistical testing-like methods. In this paper, we demonstrate that we can replace this approach by a formal verification-like method that gives…

计算工程、金融与科学 · 计算机科学 2015-01-19 Mirco Giacobbe , Calin C. Guet , Ashutosh Gupta , Thomas A. Henzinger , Tiago Paixao , Tatjana Petrov

Gene regulation is central to understanding cellular processes and development, potentially leading to the discovery of new treatments for diseases and personalized medicine. Inferring gene regulatory networks (GRNs) from single-cell RNA…

计算工程、金融与科学 · 计算机科学 2025-06-17 Tsz Pan Tong , Aoran Wang , George Panagopoulos , Jun Pang

In our study, we introduce a novel hybrid ensemble model that synergistically combines LSTM, BiLSTM, CNN, GRU, and GloVe embeddings for the classification of gene mutations in cancer. This model was rigorously tested using Kaggle's…

定量方法 · 定量生物学 2024-05-21 Sanad Aburass , Osama Dorgham , Jamil Al Shaqsi

Background: An artificial intelligence (AI)-enabled rule-out device may autonomously remove patient images unlikely to have cancer from radiologist review. Many published studies evaluate this type of device by retrospectively applying the…

统计方法学 · 统计学 2024-10-03 Kwok Lung Fan , Yee Lam Elim Thompson , Weijie Chen , Craig K. Abbey , Frank W Samuelson

Deep learning-based medical image segmentation typically relies on ground truth (GT) labels obtained through manual annotation, but these can be prone to random errors or systematic biases. This study examines the robustness of deep…

计算机视觉与模式识别 · 计算机科学 2026-04-15 Iman Islam , Bram Ruijsink , Andrew J. Reader , Andrew P. King

The state space of Android apps is huge and its thorough exploration during testing remains a major challenge. In fact, the best exploration strategy is highly dependent on the features of the app under test. Reinforcement Learning (RL) is…

软件工程 · 计算机科学 2021-12-13 Andrea Romdhana , Alessio Merlo , Mariano Ceccato , Paolo Tonella

Breast cancer has become one of the most prevalent cancers by which people all over the world are affected and is posed serious threats to human beings, in a particular woman. In order to provide effective treatment or prevention of this…

图像与视频处理 · 电气工程与系统科学 2021-07-15 Pouya Hallaj Zavareh , Atefeh Safayari , Hamidreza Bolhasani

Accurate tumor classification is essential for selecting effective treatments, but current methods have limitations. Standard tumor grading, which categorizes tumors based on cell differentiation, is not recommended as a stand-alone…

计算机视觉与模式识别 · 计算机科学 2025-02-11 Marianne Abémgnigni Njifon , Tobias Weber , Viktor Bezborodov , Tyll Krueger , Dominic Schuhmacher

In the field of Model-Driven Engineering, there exist numerous tools that support various consistency management operations including model transformation, synchronisation and consistency checking. The supported operations, however,…

软件工程 · 计算机科学 2020-12-04 Nils Weidmann , Anthony Anjorin , James Cheney

Deep learning (DL) has gained popularity in recent years as an effective tool for classifying the current health and predicting the future of industrial equipment. However, most DL models have black-box components with an underlying…

机器学习 · 计算机科学 2023-08-22 Hao Lu , Austin M. Bray , Chao Hu , Andrew T. Zimmerman , Hongyi Xu