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Imbalanced response variable distribution is a common occurrence in data science. In fields such as fraud detection, medical diagnostics, system intrusion detection and many others where abnormal behavior is rarely observed the data under…

机器学习 · 计算机科学 2019-11-21 Firuz Kamalov

We present a unified framework for quantum sensitivity sampling, extending the advantages of quantum computing to a broad class of classical approximation problems. Our unified framework provides a streamlined approach for constructing…

数据结构与算法 · 计算机科学 2025-09-23 Zhao Song , David P. Woodruff , Lichen Zhang

We present an approach to denoising spatial transcriptomics images that is particularly effective for uncovering cell identities in the regime of ultra-low sequencing depths, and also allows for interpolation of gene expression. The method…

Many common clustering methods cannot be used for clustering multivariate longitudinal data in cases where variables exhibit high autocorrelations. In this article, a copula kernel mixture model (CKMM) is proposed for clustering data of…

统计方法学 · 统计学 2025-06-23 Xi Zhang , Orla A. Murphy , Paul D. McNicholas

The study presents a novel approach for quantifying cellular interactions in digital pathology using deep learning-based image cytometry. Traditional methods struggle with the diversity and heterogeneity of cells within tissues. To address…

定量方法 · 定量生物学 2024-09-02 Toru Nagasaka , Kimihiro Yamashita , Mitsugu Fujita

We introduce a new type of test for complete spatial randomness that applies to mapped point patterns in a rectangle or a cube of any dimension. This is the first test of its kind to be based on characteristic functions and utilizes a…

统计方法学 · 统计学 2025-09-23 Yiran Zeng , Dale L. Zimmerman

We restrict our attention to space-time point pattern data for which we have a single realisation within a finite region. Second-order characteristics are used to analyse the spatio-temporal structure of the underlying point process. In…

统计理论 · 数学 2013-04-29 Edith Gabriel

The quantization error (QE) from SOM applied on time series of spatial contrast images with variable relative amount of white and dark pixel contents, as in monochromatic medical images or satellite images, is proven a reliable indicator of…

计算机与社会 · 计算机科学 2017-10-31 Birgitta Dresp-Langley , John Mwangi Wandeto

Background: It is well known that the development of cancer is caused by the accumulation of somatic mutations within the genome. For oncogenes specifically, current research suggests that there is a small set of "driver" mutations that are…

基因组学 · 定量生物学 2013-07-16 Gregory Ryslik , Yuwei Cheng , Kei-Hoi Cheung , Yorgo Modis , Hongyu Zhao

Clustering is one of the most fundamental tasks in machine learning, and the k-means clustering algorithm is perhaps one of the most widely used clustering algorithms. However, it suffers from several limitations, such as sensitivity to…

量子物理 · 物理学 2026-04-10 Syed M. Abdullah , Alisha Baba , Muhammad Siddique , Muhammad Faryad

Spatial aggregation with respect to a population distribution involves estimating aggregate quantities for a population based on an observation of individuals in a subpopulation. In this context, a geostatistical workflow must account for…

统计方法学 · 统计学 2022-07-15 John Paige , Geir-Arne Fuglstad , Andrea Riebler , Jon Wakefield

Clustering, a fundamental activity in unsupervised learning, is notoriously difficult when the feature space is high-dimensional. Fortunately, in many realistic scenarios, only a handful of features are relevant in distinguishing clusters.…

机器学习 · 统计学 2020-10-23 Zhiyue Zhang , Kenneth Lange , Jason Xu

Spatial scan statistics are well known and widely used methods for the detection of spatial clusters of events. In the field of spatial analysis of time-to-event data, several models of scan statistics have been proposed. However, these…

统计方法学 · 统计学 2022-09-02 Camille Frévent , Mohamed-Salem Ahmed , Sophie Dabo-Niang , Michaël Genin

In this paper we focus on spatial Markov population models, describing the stochastic evolution of populations of agents, explicitly modelling their spatial distribution, representing space as a discrete, finite graph. More specifically, we…

多智能体系统 · 计算机科学 2016-10-27 Luca Bortolussi , Cheng Feng

We use Topological Data Analysis tools for studying the inner organization of cells in segmented images of epithelial tissues. More specifically, for each segmented image, we compute different persistence barcodes, which codify lifetime of…

计算机视觉与模式识别 · 计算机科学 2022-04-11 N. Atienza , M. J. Jimenez , M. Soriano-Trigueros

Coresets are arguably the most popular compression paradigm for center-based clustering objectives such as $k$-means. Given a point set $P$, a coreset $\Omega$ is a small, weighted summary that preserves the cost of all candidate solutions…

数据结构与算法 · 计算机科学 2024-05-03 Nikhil Bansal , Vincent Cohen-Addad , Milind Prabhu , David Saulpic , Chris Schwiegelshohn

We introduce a family of local inhomogeneous mark-weighted summary statistics, of order two and higher, for general marked point processes. Depending on how the involved weight function is specified, these summary statistics capture…

统计方法学 · 统计学 2024-03-13 Nicoletta D'Angelo , Giada Adelfio , Jorge Mateu , Ottmar Cronie

Projective clustering is a problem with both theoretical and practical importance and has received a great deal of attentions in recent years. Given a set of points $P$ in $\mathbb{R}^{d}$ space, projective clustering is to find a set…

计算几何 · 计算机科学 2015-03-20 Hu Ding , Jinhui Xu

The identification of different homogeneous groups of observations and their appropriate analysis in PLS-SEM has become a critical issue in many appli- cation fields. Usually, both SEM and PLS-SEM assume the homogeneity of all units on…

统计方法学 · 统计学 2018-10-18 Mario Fordellone , Maurizio Vichi

Genomic regions (or loci) displaying outstanding correlation with some environmental variables are likely to be under selection and this is the rationale of recent methods of identifying selected loci and retrieving functional information…

种群与进化 · 定量生物学 2013-08-13 Gilles Guillot