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The application of supervised deep learning methods in digital pathology is limited due to their sensitivity to domain shift. Digital Pathology is an area prone to high variability due to many sources, including the common practice of…

图像与视频处理 · 电气工程与系统科学 2020-12-24 Jelica Vasiljević , Friedrich Feuerhake , Cédric Wemmert , Thomas Lampert

Histopathological images are essential for medical diagnosis and treatment planning, but interpreting them accurately using machine learning can be challenging due to variations in tissue preparation, staining and imaging protocols. Domain…

计算机视觉与模式识别 · 计算机科学 2023-11-01 Vaibhav Khamankar , Sutanu Bera , Saumik Bhattacharya , Debashis Sen , Prabir Kumar Biswas

Although unsupervised domain adaptation (UDA) is a promising direction to alleviate domain shift, they fall short of their supervised counterparts. In this work, we investigate relatively less explored semi-supervised domain adaptation…

计算机视觉与模式识别 · 计算机科学 2023-07-07 Hritam Basak , Zhaozheng Yin

Domain shift is a critical problem for pathology AI as pathology data is heavily influenced by center-specific conditions. Current pathology domain adaptation methods focus on image patches rather than WSI, thus failing to capture global…

Convolutional Neural Networks (CNNs) have achieved state-of-the-art performance for medical image segmentation, yet need plenty of manual annotations for training. Semi-Supervised Learning (SSL) methods are promising to reduce the…

计算机视觉与模式识别 · 计算机科学 2022-08-19 Ran Gu , Jingyang Zhang , Guotai Wang , Wenhui Lei , Tao Song , Xiaofan Zhang , Kang Li , Shaoting Zhang

The domain shift in pathological segmentation is an important problem, where a network trained by a source domain (collected at a specific hospital) does not work well in the target domain (from different hospitals) due to the different…

计算机视觉与模式识别 · 计算机科学 2023-04-27 Xiaoqing Liu , Kengo Araki , Shota Harada , Akihiko Yoshizawa , Kazuhiro Terada , Mariyo Kurata , Naoki Nakajima , Hiroyuki Abe , Tetsuo Ushiku , Ryoma Bise

Traditional domain generalization methods often rely on domain alignment to reduce inter-domain distribution differences and learn domain-invariant representations. However, domain shifts are inherently difficult to eliminate, which limits…

计算机视觉与模式识别 · 计算机科学 2024-12-10 Yuheng Xu , Taiping Zhang

The analysis of the tumor environment on digital histopathology slides is becoming key for the understanding of the immune response against cancer, supporting the development of novel immuno-therapies. We introduce here a novel deep…

图像与视频处理 · 电气工程与系统科学 2019-06-27 Ansh Kapil , Tobias Wiestler , Simon Lanzmich , Abraham Silva , Keith Steele , Marlon Rebelatto , Guenter Schmidt , Nicolas Brieu

We introduce a novel approach to unsupervised and semi-supervised domain adaptation for semantic segmentation. Unlike many earlier methods that rely on adversarial learning for feature alignment, we leverage contrastive learning to bridge…

计算机视觉与模式识别 · 计算机科学 2021-04-23 Weizhe Liu , David Ferstl , Samuel Schulter , Lukas Zebedin , Pascal Fua , Christian Leistner

Deep neural networks have reached remarkable achievements in medical image processing tasks, specifically in classifying and detecting various diseases. However, when confronted with limited data, these networks face a critical…

计算机视觉与模式识别 · 计算机科学 2024-09-25 Matina Mahdizadeh Sani , Ali Royat , Mahdieh Soleymani Baghshah

Semantic segmentation models struggle to generalize in the presence of domain shift. In this paper, we introduce contrastive learning for feature alignment in cross-domain adaptation. We assemble both in-domain contrastive pairs and…

计算机视觉与模式识别 · 计算机科学 2022-04-19 Feihu Zhang , Vladlen Koltun , Philip Torr , René Ranftl , Stephan R. Richter

We propose a method to improve the generalization of skin lesion classification models by combining self-supervised learning (SSL) and active domain adaptation (ADA). The main steps of the approach include selection of an SSL pre-trained…

计算机视觉与模式识别 · 计算机科学 2025-02-20 Jun Ye

We propose a two-step domain shift-invariant mitosis cell detection method based on Faster RCNN and a convolutional neural network (CNN). We generate various domain-shifted versions of existing histopathology images using a stain…

计算机视觉与模式识别 · 计算机科学 2021-09-29 Ramin Nateghi , Fattaneh Pourakpour

The insertion of deep learning in medical image analysis had lead to the development of state-of-the art strategies in several applications such a disease classification, as well as abnormality detection and segmentation. However, even the…

图像与视频处理 · 电气工程与系统科学 2022-02-24 Mauricio Orbes-Arteaga , Thomas Varsavsky , Lauge Sorensen , Mads Nielsen , Akshay Pai , Sebastien Ourselin , Marc Modat , M Jorge Cardoso

Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

图像与视频处理 · 电气工程与系统科学 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

Medical images from different healthcare centers exhibit varied data distributions, posing significant challenges for adapting lung nodule detection due to the domain shift between training and application phases. Traditional unsupervised…

计算机视觉与模式识别 · 计算机科学 2024-08-05 Haifeng Zhao , Lixiang Jiang , Leilei Ma , Dengdi Sun , Yanping Fu

We propose a novel semi-supervised learning approach for classification of histopathology images. We employ strong supervision with patch-level annotations combined with a novel co-training loss to create a semi-supervised learning…

计算机视觉与模式识别 · 计算机科学 2022-08-30 Bodong Zhang , Beatrice Knudsen , Deepika Sirohi , Alessandro Ferrero , Tolga Tasdizen

The deep learning technique has been shown to be effectively addressed several image analysis tasks in the computer-aided diagnosis scheme for mammography. The training of an efficacious deep learning model requires large data with diverse…

计算机视觉与模式识别 · 计算机科学 2023-09-08 Zheren Li , Zhiming Cui , Lichi Zhang , Sheng Wang , Chenjin Lei , Xi Ouyang , Dongdong Chen , Xiangyu Zhao , Yajia Gu , Zaiyi Liu , Chunling Liu , Dinggang Shen , Jie-Zhi Cheng

Digitization techniques for biomedical images yield different visual patterns in radiological exams. These differences may hamper the use of data-driven approaches for inference over these images, such as Deep Neural Networks. Another…

计算机视觉与模式识别 · 计算机科学 2019-12-10 Hugo Oliveira , Edemir Ferreira , Jefersson A. dos Santos

Machine learning techniques used in computer-aided medical image analysis usually suffer from the domain shift problem caused by different distributions between source/reference data and target data. As a promising solution, domain…

计算机视觉与模式识别 · 计算机科学 2021-10-26 Hao Guan , Mingxia Liu