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相关论文: Deep Neural Network-Based Prediction of B-Cell Epi…

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B-cell epitopes play a key role in stimulating B-cells, triggering the primary immune response which results in antibody production as well as the establishment of long-term immunity in the form of memory cells. Consequently, being able to…

定量方法 · 定量生物学 2021-03-23 Bhargab Ghoshal , Biraja Ghoshal , Stephen Swift , Allan Tucker

Predicting the binding of viral peptides to the major histocompatibility complex with machine learning can potentially extend the computational immunology toolkit for vaccine development, and serve as a key component in the fight against a…

定量方法 · 定量生物学 2021-04-19 Johanna Vielhaben , Markus Wenzel , Eva Weicken , Nils Strodthoff

In this work, we developed a deep learning model-based approach to forecast the spreading trend of SARS-CoV-2 in the United States. We implemented the designed model using the United States to confirm cases and state demographic data and…

计算机与社会 · 计算机科学 2020-08-14 Tong Yang , Long Sha , Justin Li , Pengyu Hong

A molecular and cellular understanding of how SARS-CoV-2 variably infects and causes severe COVID-19 remains a bottleneck in developing interventions to end the pandemic. We sought to use deep learning to study the biology of SARS-CoV-2…

机器学习 · 计算机科学 2020-12-16 Arijit Sehanobish , Neal G. Ravindra , David van Dijk

The ongoing COVID-19 pandemic continues to pose significant challenges to global public health, despite the widespread availability of vaccines. Early detection of the disease remains paramount in curbing its transmission and mitigating its…

机器学习 · 计算机科学 2024-12-05 Mohsen Asghari Ilani , Saba Moftakhar Tehran , Ashkan Kavei , Arian Radmehr

The availability of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) virus data post-COVID has reached exponentially to an enormous magnitude, opening research doors to analyze its behavior. Various studies are conducted by…

神经与进化计算 · 计算机科学 2025-01-28 Taslim Murad , Prakash Chourasia , Sarwan Ali , Imdad Ullah Khan , Murray Patterson

This technical report proposes the use of a deep convolutional neural network as a preliminary diagnostic method in the analysis of chest computed tomography images from patients with symptoms of Severe Acute Respiratory Syndrome (SARS) and…

图像与视频处理 · 电气工程与系统科学 2022-08-24 Victor Felipe Reis-Silva

Accurate in-silico prediction of conformational B-cell epitopes would lead to major improvements in disease diagnostics, drug design and vaccine development. A variety of computational methods, mainly based on machine learning approaches,…

生物大分子 · 定量生物学 2023-01-11 Gabriel Cia , Fabrizio Pucci , Marianne Rooman

The reliable and rapid identification of the COVID-19 has become crucial to prevent the rapid spread of the disease, ease lockdown restrictions and reduce pressure on public health infrastructures. Recently, several methods and techniques…

The process of identifying and characterizing B-cell epitopes, which are the portions of antigens recognized by antibodies, is important for our understanding of the immune system, and for many applications including vaccine development,…

定量方法 · 定量生物学 2025-12-10 Xiao Yuan

The novel coronavirus (SARS-CoV-2) has led to a pandemic. The current testing regime based on Reverse Transcription-Polymerase Chain Reaction for SARS-CoV-2 has been unable to keep up with testing demands, and also suffers from a relatively…

Novel Coronavirus disease (COVID-19) has abruptly and undoubtedly changed the world as we know it at the end of the 2nd decade of the 21st century. COVID-19 is extremely contagious and quickly spreading globally making its early diagnosis…

计算机视觉与模式识别 · 计算机科学 2020-04-20 Parnian Afshar , Shahin Heidarian , Farnoosh Naderkhani , Anastasia Oikonomou , Konstantinos N. Plataniotis , Arash Mohammadi

Deep Learning has achieved state of the art performance in medical imaging. However, these methods for disease detection focus exclusively on improving the accuracy of classification or predictions without quantifying uncertainty in a…

图像与视频处理 · 电气工程与系统科学 2020-03-30 Biraja Ghoshal , Allan Tucker

SARS-CoV2, which causes coronavirus disease (COVID-19) is continuing to spread globally and has become a pandemic. People have lost their lives due to the virus and the lack of counter measures in place. Given the increasing caseload and…

SARS-CoV-2 is an upper respiratory system RNA virus that has caused over 3 million deaths and infecting over 150 million worldwide as of May 2021. With thousands of strains sequenced to date, SARS-CoV-2 mutations pose significant challenges…

定量方法 · 定量生物学 2021-11-15 Yanyi Ding , Zhiyi Kuang , Yuxin Pei , Jeff Tan , Ziyu Zhang , Joseph Konan

One of the critical tools for early detection and subsequent evaluation of the incidence of lung diseases is chest radiography. This study presents a real-world implementation of a convolutional neural network (CNN) based Carebot Covid app…

图像与视频处理 · 电气工程与系统科学 2022-03-22 Daniel Kvak , Marian Bendik , Anna Chromcova

Surges that have been observed at different periods in the number of COVID-19 cases are associated with the emergence of multiple SARS-CoV-2 (Severe Acute Respiratory Virus) variants. The design of methods to support laboratory detection…

The integration of machine learning methods into bioinformatics provides particular benefits in identifying how therapeutics effective in one context might have utility in an unknown clinical context or against a novel pathology. We aim to…

机器学习 · 计算机科学 2020-06-29 Semih Cantürk , Aman Singh , Patrick St-Amant , Jason Behrmann

Artificial neural network (ANN) ability to learn, correct errors, and transform a large amount of raw data into useful medical decisions for treatment and care have increased its popularity for enhanced patient safety and quality of care.…

机器学习 · 计算机科学 2021-12-08 Muhammad Azeem , Shumaila Javaid , Hamza Fahim , Nasir Saeed

We introduce a comprehensive screening platform for the COVID-19 (a.k.a., SARS-CoV-2) pneumonia. The proposed AI-based system works on chest x-ray (CXR) images to predict whether a patient is infected with the COVID-19 disease. Although the…

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