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Accurate detection of diseased glomeruli is fundamental to progress in renal pathology and underpins the delivery of reliable clinical diagnoses. Although recent advances in computer vision have produced increasingly sophisticated detection…

计算机视觉与模式识别 · 计算机科学 2025-08-26 Tianyu Shi , Xinzi He , Kenji Ikemura , Mert R. Sabuncu , Yihe Yang , Ruining Deng

The integration of artificial intelligence (AI) into pathology is advancing precision medicine by improving diagnosis, treatment planning, and patient outcomes. Digitised whole-slide images (WSIs) capture rich spatial and morphological…

Whole-slide image (WSI) preprocessing, comprising tissue detection followed by patch extraction, is foundational to AI-driven computational pathology but remains a major bottleneck for scaling to large and heterogeneous cohorts. We present…

Automatic instance segmentation of glomeruli within kidney Whole Slide Imaging (WSI) is essential for clinical research in renal pathology. In computer vision, the end-to-end instance segmentation methods (e.g., Mask-RCNN) have shown their…

图像与视频处理 · 电气工程与系统科学 2020-07-08 Aadarsh Jha , Haichun Yang , Ruining Deng , Meghan E. Kapp , Agnes B. Fogo , Yuankai Huo

Gastrointestinal (GI) pathologies are periodically screened, biopsied, and resected using surgical tools. Usually the procedures and the treated or resected areas are not specifically tracked or analysed during or after colonoscopies.…

Segmentation has long been essential in computer vision due to its numerous real-world applications. However, most traditional deep learning and machine learning models need help to capture geometric features such as size and convexity of…

图像与视频处理 · 电气工程与系统科学 2024-12-02 Huy Trinh , Khang Tran , Nam Nguyen , Tri Cao , Binh Nguyen

Stain variability is a pervasive source of distribution shift and potential shortcut learning in renal pathology AI. We ask whether lupus nephritis glomerular lesion classifiers exploit stain as a shortcut, and how to mitigate such bias…

计算机视觉与模式识别 · 计算机科学 2026-04-13 Mohammad Daouk , Jan Ulrich Becker , Neeraja Kambham , Anthony Chang , Hien Van Nguyen , Chandra Mohan

Segmenting glomerular intraglomerular tissue and lesions traditionally depends on detailed morphological evaluations by expert nephropathologists, a labor-intensive process susceptible to interobserver variability. Our group previously…

图像与视频处理 · 电气工程与系统科学 2024-11-27 Lining Yu , Mengmeng Yin , Ruining Deng , Quan Liu , Tianyuan Yao , Can Cui , Junlin Guo , Yu Wang , Yaohong Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

Glomerulosclerosis, interstitial fibrosis, and tubular atrophy (IFTA) are histologic indicators of irrecoverable kidney injury. In standard clinical practice, the renal pathologist visually assesses, under the microscope, the percentage of…

组织与器官 · 定量生物学 2021-06-23 Brandon Ginley , Kuang-Yu Jen , Avi Rosenberg , Felicia Yen , Sanjay Jain , Agnes Fogo , Pinaki Sarder

Detecting security vulnerabilities in open-source software is a critical task that is highly regarded in the related research communities. Several approaches have been proposed in the literature for detecting vulnerable codes and…

密码学与安全 · 计算机科学 2025-07-25 Nima Atashin , Behrouz Tork Ladani , Mohammadreza Sharbaf

Deep-learning techniques have been used widely to alleviate the labour-intensive and time-consuming manual annotation required for pixel-level tissue characterization. Our previous study introduced an efficient single dynamic network -…

图像与视频处理 · 电气工程与系统科学 2023-05-25 Haoju Leng , Ruining Deng , Zuhayr Asad , R. Michael Womick , Haichun Yang , Lipeng Wan , Yuankai Huo

The application of deep learning to pathology assumes the existence of digital whole slide images of pathology slides. However, slide digitization is bottlenecked by the high cost of precise motor stages in slide scanners that are needed…

图像与视频处理 · 电气工程与系统科学 2020-11-13 Viswesh Krishna , Anirudh Joshi , Philip L. Bulterys , Eric Yang , Andrew Y. Ng , Pranav Rajpurkar

We developed a software pipeline for quality control (QC) of histopathology whole slide images (WSIs) that segments various regions, such as blurs of different levels, tissue regions, tissue folds, and pen marks. Given the necessity and…

图像与视频处理 · 电气工程与系统科学 2025-06-17 Abhijeet Patil , Garima Jain , Harsh Diwakar , Jay Sawant , Tripti Bameta , Swapnil Rane , Amit Sethi

Recent developments in AI have provided assisting tools to support pathologists' diagnoses. However, it remains challenging to incorporate such tools into pathologists' practice; one main concern is AI's insufficient workflow integration…

Accessing high-quality, open-access dermatopathology image datasets for learning and cross-referencing is a common challenge for clinicians and dermatopathology trainees. To establish a comprehensive open-access dermatopathology dataset for…

计算机视觉与模式识别 · 计算机科学 2026-02-02 Ziyang Xu , Mingquan Lin , Yiliang Zhou , Zihan Xu , Seth J. Orlow , Shane A. Meehan , Alexandra Flamm , Ata S. Moshiri , Yifan Peng

Colorectal cancer (CRC) remains a leading cause of cancer-related mortality, underscoring the importance of timely polyp detection and diagnosis. While deep learning models have improved optical-assisted diagnostics, they often demand…

信息检索 · 计算机科学 2025-07-24 Ruijie Yang , Yan Zhu , Peiyao Fu , Yizhe Zhang , Zhihua Wang , Quanlin Li , Pinghong Zhou , Xian Yang , Shuo Wang

Bladder cancer ranks within the top 10 most diagnosed cancers worldwide and is among the most expensive cancers to treat due to the high recurrence rates which require lifetime follow-ups. The primary tool for diagnosis is cystoscopy, which…

计算机视觉与模式识别 · 计算机科学 2024-03-07 Meryem Amaouche , Ouassim Karrakchou , Mounir Ghogho , Anouar El Ghazzaly , Mohamed Alami , Ahmed Ameur

Considering the profound transformation affecting pathology practice, we aimed to develop a scalable artificial intelligence (AI) system to diagnose colorectal cancer from whole-slide images (WSI). For this, we propose a deep learning (DL)…

Both CNN-based and Transformer-based object detection with bounding box representation have been extensively studied in computer vision and medical image analysis, but circular object detection in medical images is still underexplored.…

计算机视觉与模式识别 · 计算机科学 2023-09-01 Hengxu Zhang , Pengpeng Liang , Zhiyong Sun , Bo Song , Erkang Cheng

Recent advancements in Digital Pathology (DP), particularly through artificial intelligence and Foundation Models, have underscored the importance of large-scale, diverse, and richly annotated datasets. Despite their critical role, publicly…

图像与视频处理 · 电气工程与系统科学 2025-05-20 Dmitry Nechaev , Alexey Pchelnikov , Ekaterina Ivanova