中文
相关论文

相关论文: Multi Scale Graph Neural Network for Alzheimer's D…

200 篇论文

Neurological conditions, such as Alzheimer's Disease, are challenging to diagnose, particularly in the early stages where symptoms closely resemble healthy controls. Existing brain network analysis methods primarily focus on graph-based…

神经元与认知 · 定量生物学 2025-05-20 Jiaxing Xu , Kai He , Yue Tang , Wei Li , Mengcheng Lan , Xia Dong , Yiping Ke , Mengling Feng

Alzheimer's Disease destroys brain cells causing people to lose their memory, mental functions and ability to continue daily activities. It is a severe neurological brain disorder which is not curable, but earlier detection of Alzheimer's…

计算机视觉与模式识别 · 计算机科学 2017-12-21 Jyoti Islam , Yanqing Zhang

Alzheimer's disease (AD) emerges from a complex interplay of molecular, cellular, and network-level disturbances that are not easily captured by traditional reductionist frameworks. Conventional analyses of gene expression often rely on…

定量方法 · 定量生物学 2025-12-11 Aya Samadzelkava

Electroencephalography (EEG) provides a non-invasive, highly accessible, and cost-effective approach for detecting Alzheimer's disease (AD). However, existing methods, whether based on handcrafted feature engineering or standard deep…

机器学习 · 计算机科学 2026-02-03 Yihe Wang , Nan Huang , Nadia Mammone , Marco Cecchi , Xiang Zhang

Generative approaches for cross-modality transformation have recently gained significant attention in neuroimaging. While most previous work has focused on case-control data, the application of generative models to disorder-specific…

神经元与认知 · 定量生物学 2024-05-10 Reihaneh Hassanzadeh , Anees Abrol , Hamid Reza Hassanzadeh , Vince D. Calhoun

The loss of neuronal cells in the central nervous system may happen in numerous neurodegenerative illnesses. Alzheimer's Disease (AD) is an intricate, irreversible, dynamic neurodegenerative sickness. It is the main source of age-related…

神经元与认知 · 定量生物学 2016-08-29 Ankur Patel , Grishma joshi , Rupali Ugile

Alzheimer's disease (AD), as a progressive brain disease, affects cognition, memory, and behavior. Similarly, limbic-predominant age-related TDP-43 encephalopathy (LATE) is a recently defined common neurodegenerative disease that mimics the…

计算机与社会 · 计算机科学 2022-09-13 Xinxing Wu , Chong Peng , Peter T. Nelson , Qiang Cheng

Alzheimer's disease (AD) is characterized by the progressive spread of pathology across brain networks, yet forecasting this cascade at the individual level remains challenging. We present a personalized graph-based dynamical model that…

神经元与认知 · 定量生物学 2025-11-13 Chunyan Li , Yutong Mao , Xiao Liu , Wenrui Hao

As shown in computer vision, the power of deep learning lies in automatically learning relevant and powerful features for any perdition task, which is made possible through end-to-end architectures. However, deep learning approaches applied…

计算机视觉与模式识别 · 计算机科学 2018-10-02 Soheil Esmaeilzadeh , Dimitrios Ioannis Belivanis , Kilian M. Pohl , Ehsan Adeli

Alzheimer's Disease (AD) is the most common neurodegenerative disorder with one of the most complex pathogeneses, making effective and clinically actionable decision support difficult. The objective of this study was to develop a novel…

机器学习 · 计算机科学 2022-09-27 Michal Golovanevsky , Carsten Eickhoff , Ritambhara Singh

The systemic, metabolic, lifestyle factors have established associations with Alzheimer's Disease (AD) through epidemiologic and AD-specific biomarker studies. Whether colored fundus photography (CFP) contains retinal structural signatures…

计算机视觉与模式识别 · 计算机科学 2026-05-04 Seowung Leem , Yunchao Yang , Adam J. Woods , Ruogu Fang

Recent Alzheimer's disease (AD) patient studies have focused on retinal analysis, as the retina is the only part of the central nervous system which can be imaged non-invasively by optical methods. However as this is a relatively new…

Graph theoretical methods have proven valuable for investigating alterations in both anatomical and functional brain connectivity networks during Alzheimer's disease (AD). Recent studies suggest that representing brain networks in a…

神经元与认知 · 定量生物学 2025-04-04 Alice Longhena , Martin Guillemaud , Fabrizio De Vico Fallani , Raffaella Lara Migliaccio , Mario Chavez

Neurodegenerative diseases are characterized as the progressive loss of neural cells, e.g. neurons, glial cells. Ageing, monogenic variations, viral infections, and many other factors are determined and speculated as causes for them. While…

分子网络 · 定量生物学 2019-09-18 Abdulahad Bayraktar , Tugba Onal-Suzek , Baris Ethem Suzek , Omur Baysal

Alzheimer's disease (AD) is a progressive and irreversible brain disorder that unfolds over the course of 30 years. Therefore, it is critical to capture the disease progression in an early stage such that intervention can be applied before…

机器学习 · 计算机科学 2024-09-02 Yipei Wang , Bing He , Shannon Risacher , Andrew Saykin , Jingwen Yan , Xiaoqian Wang

Early detection is a crucial goal in the study of Alzheimer's Disease (AD). In this work, we describe several techniques to boost the performance of 3D deep convolutional neural networks (CNNs) trained to detect AD using structural brain…

图像与视频处理 · 电气工程与系统科学 2020-04-07 Sheng Liu , Chhavi Yadav , Carlos Fernandez-Granda , Narges Razavian

In this paper, we studied the association between the change of structural brain volumes to the potential development of Alzheimer's disease (AD). Using a simple abstraction technique, we converted regional cortical and subcortical volume…

图像与视频处理 · 电气工程与系统科学 2019-05-16 Rui Zhang , Luca Giancardo , Danilo A. Pena , Yejin Kim , Hanghang Tong , Xiaoqian Jiang

Deep learning models for medical image analysis often act as black boxes, seldom aligning with clinical guidelines or explicitly linking decisions to supporting evidence. This is especially critical in Alzheimer's disease (AD), where…

计算机视觉与模式识别 · 计算机科学 2026-02-24 Qiuhui Chen , Xuancheng Yao , Zhenglei Zhou , Xinyue Hu , Yi Hong

Alzheimers Disease AD is an acute neuro disease that degenerates the brain cells and thus leads to memory loss progressively. It is a fatal brain disease that mostly affects the elderly. It steers the decline of cognitive and biological…

机器学习 · 计算机科学 2023-04-20 Nair Bini Balakrishnan , P. S. Sreeja , Jisha Jose Panackal

In the first part of this paper we review a mathematical model for the onset and progression of Alzheimer's disease (AD) that was developed in subsequent steps over several years. The model is meant to describe the evolution of AD in vivo.…

生物物理 · 物理学 2017-09-12 Michiel Bertsch , Bruno Franchi , Maria Carla Tesi , Andrea Tosin