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Whole Slide Imaging (WSI), which involves high-resolution digital scans of pathology slides, has become the gold standard for cancer diagnosis, but its gigapixel resolution and the scarcity of annotated datasets present challenges for deep…

图像与视频处理 · 电气工程与系统科学 2025-02-03 Rita Pereira , M. Rita Verdelho , Catarina Barata , Carlos Santiago

Oral cancer is a global health challenge. It is treatable if detected early, but it is often fatal in late stages. There is a shift from the invasive and time-consuming tissue sampling and histological examination, toward non-invasive brush…

图像与视频处理 · 电气工程与系统科学 2024-10-30 Wenyi Lian , Joakim Lindblad , Christina Runow Stark , Jan-Michaél Hirsch , Nataša Sladoje

Emotions play a crucial role in human behavior and decision-making, making emotion recognition a key area of interest in human-computer interaction (HCI). This study addresses the challenges of emotion recognition by integrating facial…

计算机视觉与模式识别 · 计算机科学 2025-02-04 Zaitian Wang , Jian He , Yu Liang , Xiyuan Hu , Tianhao Peng , Kaixin Wang , Jiakai Wang , Chenlong Zhang , Weili Zhang , Shuang Niu , Xiaoyang Xie

In computational pathology, multiple instance learning (MIL) is widely used to circumvent the computational impasse in giga-pixel whole slide image (WSI) analysis. It usually consists of two stages: patch-level feature extraction and…

图像与视频处理 · 电气工程与系统科学 2023-09-21 Beidi Zhao , Wenlong Deng , Zi Han , Li , Chen Zhou , Zuhua Gao , Gang Wang , Xiaoxiao Li

Current cervical cytopathology whole slide image (WSI) screening primarily relies on detection-based approaches, which are limited in performance due to the expense and time-consuming annotation process. Multiple Instance Learning (MIL), a…

计算机视觉与模式识别 · 计算机科学 2024-07-17 Jialong Huang , Gaojie Li , Shichao Kan , Jianfeng Liu , Yixiong Liang

Increased levels of tumor infiltrating lymphocytes (TILs) in cancer tissue indicate favourable outcomes in many types of cancer. Manual quantification of immune cells is inaccurate and time consuming for pathologists. Our aim is to leverage…

Self-supervised learning (SSL) with Vision Transformers (ViT) has shown immense potential in medical image analysis. However, the quadratic complexity ($\mathcal{O}(N^2)$) of standard self-attention poses a severe barrier for…

计算机视觉与模式识别 · 计算机科学 2026-01-26 Hung Q. Vo , Pengyu Yuan , Zheng Yin , Kelvin K. Wong , Chika F. Ezeana , Son T. Ly , Hien V. Nguyen , Stephen T. C. Wong

Computational pathology involves the digitization of stained tissues into whole-slide images (WSIs) that contain billions of pixels arranged as contiguous patches. Statistical analysis of WSIs largely focuses on classification via multiple…

计算机视觉与模式识别 · 计算机科学 2026-03-24 So Won Jeong , Veronika Ročková

Whole slide imaging is fundamental to biomedical microscopy and computational pathology. Previously, learning representations for gigapixel-sized whole slide images (WSIs) has relied on multiple instance learning with weak labels, which do…

计算机视觉与模式识别 · 计算机科学 2024-05-27 Xinhai Hou , Cheng Jiang , Akhil Kondepudi , Yiwei Lyu , Asadur Chowdury , Honglak Lee , Todd C. Hollon

Multiple instance learning is qualified for many pattern recognition tasks with weakly annotated data. The combination of artificial neural network and multiple instance learning offers an end-to-end solution and has been widely utilized.…

计算机视觉与模式识别 · 计算机科学 2022-05-30 Jingjun Yi , Beichen Zhou

Multimodal Fusion Learning (MFL), leveraging disparate data from various imaging modalities (e.g., MRI, CT, SPECT), has shown great potential for addressing medical problems such as skin cancer and brain tumor prediction. However, existing…

计算机视觉与模式识别 · 计算机科学 2026-02-18 Joy Dhar , Nayyar Zaidi , Maryam Haghighat

Multi-instance learning (MIL) is a widely-applied technique in practical applications that involve complex data structures. MIL can be broadly categorized into two types: traditional methods and those based on deep learning. These…

人工智能 · 计算机科学 2023-04-25 Yu-Xuan Zhang , Zhengchun Zhou , Xingxing He , Avik Ranjan Adhikary , Bapi Dutta

One of the common and promising deep learning approaches used for medical image segmentation is transformers, as they can capture long-range dependencies among the pixels by utilizing self-attention. Despite being successful in medical…

计算机视觉与模式识别 · 计算机科学 2023-11-01 Md Motiur Rahman , Shiva Shokouhmand , Smriti Bhatt , Miad Faezipour

The burgeoning discipline of computational pathology shows promise in harnessing whole slide images (WSIs) to quantify morphological heterogeneity and develop objective prognostic modes for human cancers. However, progress is impeded by the…

计算机视觉与模式识别 · 计算机科学 2025-10-20 Chao Tu , Kun Huang , Jie Zhang , Qianjin Feng , Yu Zhang , Zhenyuan Ning

Multiple-instance Learning (MIL) is commonly used to undertake computational pathology (CPath) tasks, and the use of multi-scale patches allows diverse features across scales to be learned. Previous studies using multi-scale features in…

计算机视觉与模式识别 · 计算机科学 2026-02-03 Shuyang Wu , Yifu Qiu , Ines P. Nearchou , Sandrine Prost , Jonathan A Fallowfield , Hakan Bilen , Timothy J Kendall

Chest X-ray images are commonly used in medical diagnosis, and AI models have been developed to assist with the interpretation of these images. However, many of these models rely on information from a single view of the X-ray, while…

计算机视觉与模式识别 · 计算机科学 2023-02-24 Lucas Wannenmacher , Michael Fitzke , Diane Wilson , Andre Dourson

Advancements in digital imaging technologies have sparked increased interest in using multiplexed immunofluorescence (mIF) images to visualise and identify the interactions between specific immunophenotypes with the tumour microenvironment…

图像与视频处理 · 电气工程与系统科学 2024-07-01 Piumi Sandarenu , Julia Chen , Iveta Slapetova , Lois Browne , Peter H. Graham , Alexander Swarbrick , Ewan K. A. Millar , Yang Song , Erik Meijering

We introduce Multi-scale Adaptive Recurrent Biomedical Linear-time Encoder (MARBLE), the first \textit{purely Mamba-based} multi-state multiple instance learning (MIL) framework for whole-slide image (WSI) analysis. MARBLE processes…

计算机视觉与模式识别 · 计算机科学 2026-02-04 Jagan Mohan Reddy Dwarampudi , Joshua Wong , Hien Van Nguyen , Tania Banerjee

For the first time, we propose using a multiple instance learning based convolution-free transformer model, called Multiple Instance Neuroimage Transformer (MINiT), for the classification of T1weighted (T1w) MRIs. We first present several…

计算机视觉与模式识别 · 计算机科学 2023-11-27 Ayush Singla , Qingyu Zhao , Daniel K. Do , Yuyin Zhou , Kilian M. Pohl , Ehsan Adeli

Tissue phenotyping is a fundamental task in learning objective characterizations of histopathologic biomarkers within the tumor-immune microenvironment in cancer pathology. However, whole-slide imaging (WSI) is a complex computer vision in…

计算机视觉与模式识别 · 计算机科学 2022-03-02 Richard J. Chen , Rahul G. Krishnan