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In epidemiological research, modeling the cumulative effects of time-dependent exposures on survival outcomes presents a challenge due to their intricate temporal dynamics. Conventional spline-based statistical methods, though effective,…

机器学习 · 计算机科学 2026-01-01 Kang-Chung Yang , Shinsheng Yuan

In many applications concerning statistical graphical models the data originate from several subpopulations that share similarities but have also significant differences. This raises the question of how to estimate several graphical models…

统计方法学 · 统计学 2022-06-17 Ilias Moysidis , Bing Li

Measurements are generally collected as unilateral or bilateral data in clinical trials or observational studies. For example, in ophthalmology studies, the primary outcome is often obtained from one eye or both eyes of an individual. In…

统计方法学 · 统计学 2021-11-01 Kejia Wang , Chang-Xing Ma

Quantitative evidence synthesis methods aim to combine data from multiple medical trials to infer relative effects of different interventions. A challenge arises when trials report continuous outcomes on different measurement scales. To…

统计方法学 · 统计学 2024-02-29 Annabel L Davies , A E Ades , Julian PT Higgins

The manuscript discusses how to incorporate random effects for quantile regression models for clustered data with focus on settings with many but small clusters. The paper has three contributions: (i) documenting that existing methods may…

统计方法学 · 统计学 2022-02-24 Maria Laura Battagliola , Helle Sørensen , Anders Tolver , Ana-Maria Staicu

Comparative meta-analyses of groups of subjects by integrating multiple observational studies rely on estimated propensity scores (PSs) to mitigate covariate imbalances. However, PS estimation grapples with the theoretical and practical…

统计方法学 · 统计学 2024-05-09 Subharup Guha , Yi Li

Photoplethysmographic (PPG) signals offer diagnostic potential beyond heart rate analysis or blood oxygen level monitoring. In the recent past, research focused extensively on non-invasive PPG-based approaches to blood pressure (BP)…

计算机视觉与模式识别 · 计算机科学 2022-04-13 Fabian Schrumpf , Paul Rudi Serdack , Mirco Fuchs

Conventional survival analysis approaches estimate risk scores or individualized time-to-event distributions conditioned on covariates. In practice, there is often great population-level phenotypic heterogeneity, resulting from (unknown)…

机器学习 · 统计学 2020-03-03 Paidamoyo Chapfuwa , Chunyuan Li , Nikhil Mehta , Lawrence Carin , Ricardo Henao

Representative risk estimation is fundamental to clinical decision-making. However, risks are often estimated from non-representative epidemiologic studies, which usually underrepresent minorities. "Model-based" methods use population…

统计方法学 · 统计学 2023-04-12 Lingxiao Wang , Yan Li , Barry I. Graubard , Hormuzd A. Katki

National surveys of the healthcare system in the United States were conducted to characterize the structure of healthcare system and investigate the impact of evidence-based innovations in healthcare systems on healthcare services.…

统计方法学 · 统计学 2023-09-26 Seho Park , Brianna L Hardy , A James OMalley

Uplift modeling estimates the causal effect of an intervention as the difference between potential outcomes under treatment and control, whereas counterfactual identification aims to recover the joint distribution of these potential…

机器学习 · 计算机科学 2025-12-10 Théo Verhelst , Gianluca Bontempi

Survival analysis is essential for studying time-to-event outcomes and providing a dynamic understanding of the probability of an event occurring over time. Various survival analysis techniques, from traditional statistical models to…

机器学习 · 计算机科学 2024-03-13 Ziwen Wang , Jin Wee Lee , Tanujit Chakraborty , Yilin Ning , Mingxuan Liu , Feng Xie , Marcus Eng Hock Ong , Nan Liu

A central theme in the field of survey statistics is estimating population-level quantities through data coming from potentially non-representative samples of the population. Multilevel Regression and Poststratification (MRP), a model-based…

统计方法学 · 统计学 2020-07-17 Yuxiang Gao , Lauren Kennedy , Daniel Simpson , Andrew Gelman

Percentage coefficient (bp) has emerged in recent publications as an additional and alternative estimator of effect size for regression analysis. This paper retraces the theory behind the estimator. It's posited that an estimator must first…

应用统计 · 统计学 2024-05-07 Xinshu Zhao , Dianshi Moses Li , Ze Zack Lai , Piper Liping Liu , Song Harris Ao , Fei You

This paper deals with the derivation of a collective model of cell populations out of an individual-based description of the underlying physical particle system. By looking at the spatial distribution of cells in terms of time-evolving…

数学物理 · 物理学 2014-11-12 Annachiara Colombi , Marco Scianna , Andrea Tosin

This paper introduces aggregate Bayesian Causal Forests (aBCF), a new Bayesian model for causal inference using aggregated data. Aggregated data are common in policy evaluations where we observe individuals such as students, but…

Multiple outcomes, both continuous and discrete, are routinely gathered on subjects in longitudinal studies and during routine clinical follow-up in general. To motivate our work, we consider a longitudinal study on patients with primary…

应用统计 · 统计学 2013-04-17 Arnošt Komárek , Lenka Komárková

Estimating causal effects in a target population with unmeasured confounders is challenging, especially when instrumental variables (IVs) are unavailable. However, IVs from auxiliary populations with similar problems can help infer causal…

统计方法学 · 统计学 2025-08-06 Wei Li , Jiapeng Liu , Peng Ding , Zhi Geng

Measuring disease progression in clinical trials for testing novel treatments for multifaceted diseases as Progressive Supranuclear Palsy (PSP), remains challenging. In this study we assess a range of statistical approaches to compare…

Medical prediction applications often need to deal with small sample sizes compared to the number of covariates. Such data pose problems for prediction and variable selection, especially when the covariate-response relationship is…

机器学习 · 统计学 2024-11-05 Jeroen M. Goedhart , Thomas Klausch , Jurriaan Janssen , Mark A. van de Wiel