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We study the problem of model selection in causal inference, specifically for conditional average treatment effect (CATE) estimation. Unlike machine learning, there is no perfect analogue of cross-validation for model selection as we do not…

机器学习 · 计算机科学 2024-04-30 Divyat Mahajan , Ioannis Mitliagkas , Brady Neal , Vasilis Syrgkanis

Reward models (RMs) are fundamental to aligning Large Language Models (LLMs) via human feedback, yet they often suffer from reward hacking. They tend to latch on to superficial or spurious attributes, such as response length or formatting,…

Root cause analysis (RCA) in complex systems is challenging due to error propagation across multiple variables, the need for structural causal knowledge, and the computational cost of inference at test time. We introduce PRIM (Prior-fitted…

机器学习 · 计算机科学 2026-05-29 Christopher Lohse , Anish Dhir , Amadou Ba , Bradley Eck , Marco Ruffini , Jonas Wahl

This thesis develops methods for causal inference and causal representation learning (CRL) in high-dimensional, time-varying data. The first contribution introduces the Causal Dynamic Variational Autoencoder (CDVAE), a model for estimating…

机器学习 · 统计学 2025-12-05 Mouad EL Bouchattaoui

Predicting the impact of genomic and drug perturbations in cellular function is crucial for understanding gene functions and drug effects, ultimately leading to improved therapies. To this end, Causal Representation Learning (CRL)…

The growing demand for personalized decision-making has led to a surge of interest in estimating the Conditional Average Treatment Effect (CATE). Various types of CATE estimators have been developed with advancements in machine learning and…

机器学习 · 计算机科学 2024-11-04 Yiyan Huang , Cheuk Hang Leung , Siyi Wang , Yijun Li , Qi Wu

Learning causal relationships from time series data is an important but challenging problem. Existing synthetic datasets often contain hidden artifacts that can be exploited by causal discovery methods, reducing their usefulness for…

机器学习 · 计算机科学 2026-03-23 Xiaoyu He , Petr Ryšavý , Jakub Mareček

We present Causal Posterior Estimation (CPE), a novel method for Bayesian inference in simulator models, i.e., models where the evaluation of the likelihood function is intractable or too computationally expensive, but where one can…

机器学习 · 计算机科学 2025-05-28 Simon Dirmeier , Antonietta Mira

Traditional statistical inference in cluster randomized trials typically invokes the asymptotic theory that requires the number of clusters to approach infinity. In this article, we propose an alternative conformal causal inference…

统计方法学 · 统计学 2024-10-03 Bingkai Wang , Fan Li , Mengxin Yu

The conditional average treatment effect (CATE) is the best measure of individual causal effects given baseline covariates. However, the CATE only captures the (conditional) average, and can overlook risks and tail events, which are…

机器学习 · 统计学 2025-06-05 Nathan Kallus , Miruna Oprescu

Causal inference is essential for developing and evaluating medical interventions, yet real-world medical datasets are often difficult to access due to regulatory barriers. This makes synthetic data a potentially valuable asset that enables…

This paper provides a link between causal inference and machine learning techniques - specifically, Classification and Regression Trees (CART) - in observational studies where the receipt of the treatment is not randomized, but the…

机器学习 · 计算机科学 2019-05-23 Falco J. Bargagli-Stoffi , Giorgio Gnecco

Causal inference, estimating causal effects from observational data, is a fundamental tool in many disciplines. Of particular importance across a variety of domains is the continuous treatment setting, where the variable of intervention has…

机器学习 · 计算机科学 2026-05-15 Christopher Stith , Medha Barath , Vahid Balazadeh , Jesse C. Cresswell , Rahul G. Krishnan

Statistical machine learning algorithms have achieved state-of-the-art results on benchmark datasets, outperforming humans in many tasks. However, the out-of-distribution data and confounder, which have an unpredictable causal relationship,…

计算机视觉与模式识别 · 计算机科学 2022-10-31 Changjie Lu

Randomised controlled trials (RCTs) are regarded as the gold standard for estimating causal treatment effects on health outcomes. However, RCTs are not always feasible, because of time, budget or ethical constraints. Observational data such…

统计方法学 · 统计学 2024-02-20 Li Su , Roonak Rezvani , Shaun R. Seaman , Colin Starr , Isaac Gravestock

While recent debiasing methods for Scene Graph Generation (SGG) have shown impressive performance, these efforts often attribute model bias solely to the long-tail distribution of relationships, overlooking the more profound causes stemming…

计算机视觉与模式识别 · 计算机科学 2025-03-25 Li Liu , Shuzhou Sun , Shuaifeng Zhi , Fan Shi , Zhen Liu , Janne Heikkilä , Yongxiang Liu

Precision rehabilitation offers the promise of an evidence-based approach for optimizing individual rehabilitation to improve long-term functional outcomes. Emerging techniques, including those driven by artificial intelligence, are rapidly…

Dynamic treatment regimes (DTRs) are used in medicine to tailor sequential treatment decisions to patients by considering patient heterogeneity. Common methods for learning optimal DTRs, however, have shortcomings: they are typically based…

机器学习 · 统计学 2023-06-21 Theresa Blümlein , Joel Persson , Stefan Feuerriegel

Recent developments in generative artificial intelligence (AI) rely on machine learning techniques such as deep learning and generative modeling to achieve state-of-the-art performance across wide-ranging domains. These methods' surprising…

机器学习 · 统计学 2026-01-27 Gemma E. Moran , Bryon Aragam

Clinical trials provide essential guidance for practicing Evidence-Based Medicine, though often accompanying with unendurable costs and risks. To optimize the design of clinical trials, we introduce a novel Clinical Trial Result Prediction…

计算与语言 · 计算机科学 2020-10-13 Qiao Jin , Chuanqi Tan , Mosha Chen , Xiaozhong Liu , Songfang Huang