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The human brain is a complex system defined by multi-way, higher-order interactions invisible to traditional pairwise network models. Although a diverse array of analytical methods has been developed to address this shortcoming, the field…

定量方法 · 定量生物学 2025-11-11 Mohamma Reza Salehi , Ali BashirGonbadi , Hamid Soltanian-Zadeh

Our goal in this paper is to leverage the potential of the topological signal processing (TSP) framework for analyzing brain networks. Representing brain data as signals over simplicial complexes allows us to capture higher-order…

信号处理 · 电气工程与系统科学 2025-04-11 Breno C. Bispo , Stefania Sardellitti , Fernando A. N. Santos , Juliano B. Lima

In brain network analysis using resting-state fMRI, there is growing interest in modeling higher-order interactions beyond simple pairwise connectivity via persistent homology. Despite the promise of these advanced topological tools, robust…

神经元与认知 · 定量生物学 2025-03-20 Moo K. Chung , Anass B. El-Yaagoubi , Anqi Qiu , Hernando Ombao

Networks are a fundamental tool for understanding and modeling complex systems in physics, biology, neuroscience, engineering, and social science. Many networks are known to exhibit rich, lower-order connectivity patterns that can be…

社会与信息网络 · 计算机科学 2018-01-08 Austin R. Benson , David F. Gleich , Jure Leskovec

A social interaction (so-called higher-order event/interaction) can be regarded as the activation of the hyperlink among the corresponding individuals. Social interactions can be, thus, represented as higher-order temporal networks, that…

物理与社会 · 物理学 2024-08-12 H. A. Bart Peters , Alberto Ceria , Huijuan Wang

Brain connectomics is still largely dominated by pairwise-based models, such as graphs, which cannot represent circulatory or higher-order functional interactions. In this paper, we propose a multimodal framework based on Topological Signal…

神经元与认知 · 定量生物学 2026-04-01 Breno C. Bispo , Stefania Sardellitti , Juliano B. Lima , Fernando A. N. Santos

The irreducible complexity of natural phenomena has led Graph Neural Networks to be employed as a standard model to perform representation learning tasks on graph-structured data. While their capacity to capture local and global patterns is…

机器学习 · 计算机科学 2024-02-13 Lorenzo Giusti

Networks provide a powerful formalism for modeling complex systems by using a model of pairwise interactions. But much of the structure within these systems involves interactions that take place among more than two nodes at once; for…

社会与信息网络 · 计算机科学 2018-12-13 Austin R. Benson , Rediet Abebe , Michael T. Schaub , Ali Jadbabaie , Jon Kleinberg

The study of irreducible higher-order interactions has become a core topic of study in complex systems. Two of the most well-developed frameworks, topological data analysis and multivariate information theory, aim to provide formal tools…

信息论 · 计算机科学 2025-04-15 Thomas F. Varley , Pedro A. M. Mediano , Alice Patania , Josh Bongard

A social interaction (so-called higher-order event/interaction) can be regarded as the activation of the hyperlink among the corresponding individuals. Social interactions can be, thus, represented as higher-order temporal networks, that…

物理与社会 · 物理学 2024-12-17 Mathieu Jung-Muller , Alberto Ceria , Huijuan Wang

Several approaches to cognition and intelligence research rely on statistics-based models testing, namely factor analysis. In the present work we exploit the emerging dynamical systems perspective putting the focus on the role of the…

物理与社会 · 物理学 2018-03-15 Gemma Rosell-Tarragó , Emanuele Cozzo , Albert Díaz-Guilera

Higher-order connectivity in complex systems described by simplexes of different orders provides a geometry for simplex-based dynamical variables and interactions. Simplicial complexes that constitute a functional geometry of the human…

神经元与认知 · 定量生物学 2020-06-19 Miroslav Andjelkovic , Bosiljka Tadic , Roderick Melnik

Understanding the common topological characteristics of the human brain network across a population is central to understanding brain functions. The abstraction of human connectome as a graph has been pivotal in gaining insights on the…

定量方法 · 定量生物学 2023-04-26 Soumya Das , D. Vijay Anand , Moo K. Chung

Complex systems, such as economic, social, biological, and ecological systems, usually feature interactions not only between pairwise entities but also among three or more entities. These multi-entity interactions are known as higher-order…

物理与社会 · 物理学 2025-06-06 Junhap Bian , Tao Zhou , Yilin Bi

Recurrent Neural Network models have elucidated the interplay between structure and dynamics in biological neural networks, particularly the emergence of irregular and rhythmic activities in cortex. However, most studies have focused on…

神经元与认知 · 定量生物学 2025-09-04 Nimrod Sherf , Xaq Pitkow , Krešimir Josić , Kevin E. Bassler

The brain's complex functionality emerges from network interactions that go beyond dyadic connections, with higher-order interactions significantly contributing to this complexity. One method of capturing higher-order interactions is…

神经元与认知 · 定量生物学 2024-06-11 Behdad Khodabandehloo , Payam Jannatdoust , Babak Nadjar Araabi

Collective behavior plays a key role in the function of a wide range of physical, biological, and neurological systems where empirical evidence has recently uncovered the prevalence of higher-order interactions, i.e., structures that…

适应与自组织系统 · 物理学 2022-06-14 Per Sebastian Skardal , Lluís Arola-Fernández , Dane Taylor , Alex Arenas

Complex systems in the real world can be modeled as a network of connected components. The human brain, as a network of neurons among which the interactions cause perception, is a complex network. Synchronization is a dynamical phenomenon…

生物物理 · 物理学 2019-04-30 Arefeh Mazarei , Mohammad Amirian Matlob , Gholamhossein Riazi , Yousef Jamali

To meet ongoing cognitive demands, the human brain must seamlessly transition from one brain state to another, in the process drawing on different cognitive systems. How does the brain's network of anatomical connections help facilitate…

神经元与认知 · 定量生物学 2016-09-08 Richard F. Betzel , Shi Gu , John D. Medaglia , Fabio Pasqualetti , Danielle S. Bassett

Functional networks provide a topological description of activity patterns in the brain, as they stem from the propagation of neural activity on the underlying anatomical or structural network of synaptic connections. This latter is well…

无序系统与神经网络 · 物理学 2021-02-11 Ali Safari , Paolo Moretti , Ibai Diez , Jesus M. Cortes , Miguel Ángel Muñoz
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