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The brain must extract behaviorally relevant latent variables from the signals streamed by the sensory organs. Such latent variables are often encoded in the dynamics that generated the signal rather than in the specific realization of the…

神经元与认知 · 定量生物学 2021-10-07 Tiberiu Tesileanu , Siavash Golkar , Samaneh Nasiri , Anirvan M. Sengupta , Dmitri B. Chklovskii

People segment complex, ever-changing and continuous experience into basic, stable and discrete spatio-temporal experience units, called events. Event segmentation literature investigates the mechanisms that allow people to extract events.…

神经元与认知 · 定量生物学 2022-10-13 Hamit Basgol , Inci Ayhan , Emre Ugur

Neural population activity often exhibits rich variability and temporal structure. This variability is thought to arise from single-neuron stochasticity, neural dynamics on short time-scales, as well as from modulations of neural firing…

机器学习 · 统计学 2014-10-14 Mijung Park , Jakob H. Macke

Understanding the functioning of a neural system in terms of its underlying circuitry is an important problem in neuroscience. Recent developments in electrophysiology and imaging allow one to simultaneously record activities of hundreds of…

数据库 · 计算机科学 2008-03-11 Debprakash Patnaik , P. S. Sastry , K. P. Unnikrishnan

`Bursting', defined as periods of high frequency firing of a neuron separated by periods of quiescence, has been observed in various neuronal systems, both \textit{in vitro} and \textit{in vivo}. It has been associated with a range of…

神经元与认知 · 定量生物学 2018-06-20 E. Cotterill , S. J. Eglen

Sequential activation of neurons is a common feature of network activity during a variety of behaviors, including working memory and decision making. Previous network models for sequences and memory emphasized specialized architectures in…

神经元与认知 · 定量生物学 2016-03-16 Kanaka Rajan , Christopher D Harvey , David W Tank

Identifying the spatio-temporal network structure of brain activity from multi-neuronal data streams is one of the biggest challenges in neuroscience. Repeating patterns of precisely timed activity across a group of neurons is potentially…

神经元与认知 · 定量生物学 2009-03-03 Casey Diekman , Kohinoor Dasgupta , Vijay Nair , P. S. Sastry , K. P. Unnikrishnan

Modeling and parameter estimation for neuronal dynamics are often challenging because many parameters can range over orders of magnitude and are difficult to measure experimentally. Moreover, selecting a suitable model complexity requires a…

动力系统 · 数学 2018-01-31 J. E. Rubin , B. Krauskopf , H. M. Osinga

Currently we routinely develop a complex neuronal network to explain observed but often paradoxical phenomena based upon biological recordings. Here we present a general approach to demonstrate how to mathematically tackle such a complex…

定量方法 · 定量生物学 2015-06-03 Yu Wu , Wenlian Lu , Wei Lin , Gareth Leng , Jianfeng Feng

Discrete-time modeling of acoustic, mechanical and electrical systems is a prominent topic in the musical signal processing literature. Such models are mostly derived by discretizing a mathematical model, given in terms of ordinary or…

In this paper we present a simple microscopic stochastic model describing short term plasticity within a large homogeneous network of interacting neurons. Each neuron is represented by its membrane potential and by the residual calcium…

概率论 · 数学 2020-01-29 Antonio Galves , Eva Löcherbach , Christophe Pouzat , Errico Presutti

In this paper we address the question of statistical model selection for a class of stochastic models of biological neural nets. Models in this class are systems of interacting chains with memory of variable length. Each chain describes the…

统计理论 · 数学 2018-12-19 A. Duarte , A. Galves , E. Löcherbach , G. Ost

Discovering frequent episodes in event sequences is an interesting data mining task. In this paper, we argue that this framework is very effective for analyzing multi-neuronal spike train data. Analyzing spike train data is an important…

数据库 · 计算机科学 2008-03-10 Debprakash Patnaik , P. S. Sastry , K. P. Unnikrishnan

This paper introduces a class of stochastic models of interacting neurons with emergent dynamics similar to those seen in local cortical populations, and compares them to very simple reduced models driven by the same mean excitatory and…

神经元与认知 · 定量生物学 2017-11-07 Yao Li , Logan Chariker , Lai-Sang Young

We study the problem of graph structure identification, i.e., of recovering the graph of dependencies among time series. We model these time series data as components of the state of linear stochastic networked dynamical systems. We assume…

机器学习 · 计算机科学 2023-06-29 Sérgio Machado , Anirudh Sridhar , Paulo Gil , Jorge Henriques , José M. F. Moura , Augusto Santos

Neural networks are able to extract information from the timing of spikes. Here we provide new results on the behavior of the simplest neuronal model which is able to decode information embedded in temporal spike patterns, the so called…

无序系统与神经网络 · 物理学 2015-06-17 Carlo Baldassi , Alfredo Braunstein , Riccardo Zecchina

The firing dynamics of biological neurons in mathematical models is often determined by the model's parameters, representing the neurons' underlying properties. The parameter estimation problem seeks to recover those parameters of a single…

神经元与认知 · 定量生物学 2022-10-05 Long Le , Yao Li

Segmentations are often necessary for the analysis of image data. They are used to identify different objects, for example cell nuclei, mitochondria, or complete cells in microscopic images. There might be features in the data, that cannot…

计算几何 · 计算机科学 2016-05-31 Julia Portl , Heike Leitte

Plasticity is one of the most important properties of the nervous system, which enables animals to adjust their behavior to the ever-changing external environment. Changes in synaptic efficacy between neurons constitute one of the major…

神经元与认知 · 定量生物学 2018-01-23 Taishi Iwasaki , Hideitsu Hino , Masami Tatsuno , Shotaro Akaho , Noboru Murata

Individual neurons often produce highly variable responses over nominally identical trials, reflecting a mixture of intrinsic "noise" and systematic changes in the animal's cognitive and behavioral state. Disentangling these sources of…

神经元与认知 · 定量生物学 2021-11-08 Alex H. Williams , Scott W. Linderman
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