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Computationally explicit hypotheses of brain function derived from machine learning (ML)-based models have recently revolutionized neuroscience. Despite the unprecedented ability of these artificial neural networks (ANNs) to capture…

神经元与认知 · 定量生物学 2023-12-12 Kohitij Kar , Simon Kornblith , Evelina Fedorenko

Recently, deep learning has been advancing the state of the art in artificial intelligence to a new level, and humans rely on artificial intelligence techniques more than ever. However, even with such unprecedented advancements, the lack of…

人机交互 · 计算机科学 2018-04-10 Jaegul Choo , Shixia Liu

Mechanistic interpretability aims to explain neural model behaviour by reverse-engineering learned computational structure into human-understandable components. Without a formal framework, however, mechanistic explanations cannot be…

机器学习 · 计算机科学 2026-05-12 Ward Gauderis , Thomas Dooms , Steven T. Holmer , Kola Ayonrinde , Geraint A. Wiggins

Multi-modal large language models (MLLMs) have shown promise in advancing healthcare. However, most existing models remain confined to single-image understanding, which greatly limits their applicability in clinical workflows. In practice,…

计算机视觉与模式识别 · 计算机科学 2025-12-01 Zhen Chen , Yihang Fu , Gabriel Madera , Mauro Giuffre , Serina Applebaum , Hyunjae Kim , Hua Xu , Qingyu Chen

The interpretability of deep neural networks has become a subject of great interest within the medical and healthcare domain. This attention stems from concerns regarding transparency, legal and ethical considerations, and the medical…

图像与视频处理 · 电气工程与系统科学 2023-11-20 Mahbub Ul Alam , Jaakko Hollmén , Jón Rúnar Baldvinsson , Rahim Rahmani

As machine learning models become increasingly prevalent in medical diagnostics, the need for interpretability and transparency becomes paramount. The XAI Renaissance signifies a significant shift in the field, aiming to redefine the…

机器学习 · 计算机科学 2023-06-05 Sujith K Mandala

Multi-graph learning is crucial for extracting meaningful signals from collections of heterogeneous graphs. However, effectively integrating information across graphs with differing topologies, scales, and semantics, often in the absence of…

机器学习 · 计算机科学 2026-02-02 Zahra Moslemi , Ziyi Liang , Norbert Fortin , Babak Shahbaba

Predicting high-dimensional or extreme multilabels, such as in medical coding, requires both accuracy and interpretability. Existing works often rely on local interpretability methods, failing to provide comprehensive explanations of the…

计算与语言 · 计算机科学 2025-03-25 John Wu , David Wu , Jimeng Sun

The remarkable performance of the Transformer architecture in natural language processing has recently also triggered broad interest in Computer Vision. Among other merits, Transformers are witnessed as capable of learning long-range…

计算机视觉与模式识别 · 计算机科学 2023-11-07 Reza Azad , Amirhossein Kazerouni , Moein Heidari , Ehsan Khodapanah Aghdam , Amirali Molaei , Yiwei Jia , Abin Jose , Rijo Roy , Dorit Merhof

We present a novel method for quantifying the microscopic structure of brain tissue. It is based on the automated recognition of interpretable features obtained by analyzing the shapes of cells. This contrasts with prevailing methods of…

计算机视觉与模式识别 · 计算机科学 2024-04-10 Kui Qian , Litao Qiao , Beth Friedman , Edward O'Donnell , David Kleinfeld , Yoav Freund

The field of medical diagnosis has undergone a significant transformation with the advent of large language models (LLMs), yet the challenges of interpretability within these models remain largely unaddressed. This study introduces…

计算与语言 · 计算机科学 2024-09-17 Junying Chen , Chi Gui , Anningzhe Gao , Ke Ji , Xidong Wang , Xiang Wan , Benyou Wang

Mechanistic Interpretability aims to understand neural networks through causal explanations. We argue for the Explanatory View Hypothesis: that Mechanistic Interpretability research is a principled approach to understanding models because…

机器学习 · 计算机科学 2025-05-05 Kola Ayonrinde , Louis Jaburi

Large language models (LLMs) have achieved remarkable capabilities across diverse tasks, yet their internal decision-making processes remain largely opaque. Mechanistic interpretability (i.e., the systematic study of how neural networks…

计算与语言 · 计算机科学 2026-02-13 Usman Naseem

Adopting Convolutional Neural Networks (CNNs) in the daily routine of primary diagnosis requires not only near-perfect precision, but also a sufficient degree of generalization to data acquisition shifts and transparency. Existing CNN…

计算机视觉与模式识别 · 计算机科学 2023-06-22 Mara Graziani , Sebastian Otalora , Stephane Marchand-Maillet , Henning Muller , Vincent Andrearczyk

Feature-based methods are commonly used to explain model predictions, but these methods often implicitly assume that interpretable features are readily available. However, this is often not the case for high-dimensional data, and it can be…

As the foundation of current natural language processing methods, pre-trained language model has achieved excellent performance. However, the black-box structure of the deep neural network in pre-trained language models seriously limits the…

计算与语言 · 计算机科学 2023-06-28 Fanyu Wang , Zhenping Xie

Large language models (LLMs) show promise for supporting clinicians in diagnostic communication by generating explanations and guidance for patients. Yet their ability to produce outputs that are both understandable and empathetic remains…

计算与语言 · 计算机科学 2025-11-04 Jianzhou Yao , Shunchang Liu , Guillaume Drui , Rikard Pettersson , Alessandro Blasimme , Sara Kijewski

Interpretability methods aim to help users build trust in and understand the capabilities of machine learning models. However, existing approaches often rely on abstract, complex visualizations that poorly map to the task at hand or require…

人机交互 · 计算机科学 2021-07-12 Harini Suresh , Kathleen M. Lewis , John V. Guttag , Arvind Satyanarayan

We introduce Mediffusion -- a new method for semi-supervised learning with explainable classification based on a joint diffusion model. The medical imaging domain faces unique challenges due to scarce data labelling -- insufficient for…

计算机视觉与模式识别 · 计算机科学 2024-11-15 Joanna Kaleta , Paweł Skierś , Jan Dubiński , Przemysław Korzeniowski , Kamil Deja

Recently, developing unified medical image segmentation models gains increasing attention, especially with the advent of the Segment Anything Model (SAM). SAM has shown promising binary segmentation performance in natural domains, however,…

计算机视觉与模式识别 · 计算机科学 2024-12-18 Shuangping Huang , Hao Liang , Qingfeng Wang , Chulong Zhong , Zijian Zhou , Miaojing Shi
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