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It has been shown in the literature that marijuana use is associated with changes in brain network connectivity. We propose large-scale Extended Granger Causality (lsXGC) and investigate whether it can capture such changes using…

机器学习 · 计算机科学 2021-01-07 M. Ali Vosoughi , Axel Wismuller

We introduce large-scale Augmented Granger Causality (lsAGC) as a method for connectivity analysis in complex systems. The lsAGC algorithm combines dimension reduction with source time-series augmentation and uses predictive time-series…

神经元与认知 · 定量生物学 2021-01-26 Axel Wismuller , M. Ali Vosoughi

The literature manifests that schizophrenia is associated with alterations in brain network connectivity. We investigate whether large-scale Extended Granger Causality (lsXGC) can capture such alterations using resting-state fMRI data. Our…

神经元与认知 · 定量生物学 2021-01-27 Axel Wismüller , M. Ali Vosoughi

The excessive consumption of marijuana can induce substantial psychological and social consequences. In this investigation, we propose an elucidative framework termed high-order graph attention neural networks (HOGANN) for the…

神经元与认知 · 定量生物学 2024-09-10 Jun-En Ding , Shihao Yang , Anna Zilverstand , Kaustubh R. Kulkarni , Xiaosi Gu , Feng Liu

It is a challenging research endeavor to infer causal relationships in multivariate observational time-series. Such data may be represented by graphs, where nodes represent time-series, and edges directed causal influence scores between…

信息论 · 计算机科学 2022-05-09 Axel Wismüller , Ali Vosoughi , Adora DSouza , Anas Abidin

To gain insight into complex systems it is a key challenge to infer nonlinear causal directional relations from observational time-series data. Specifically, estimating causal relationships between interacting components in large systems…

机器学习 · 计算机科学 2021-11-04 Axel Wismüller , Adora M. DSouza , Anas Z. Abidin

Graph topology inference of network processes with co-evolving and interacting time-series is crucial for network studies. Vector autoregressive models (VAR) are popular approaches for topology inference of directed graphs; however, in…

机器学习 · 计算机科学 2020-11-18 M. Ali Vosoughi , Axel Wismuller

Functional MRI is a neuroimaging technique that analyzes the functional activity of the brain by measuring blood-oxygen-level-dependent signals throughout the brain. The derived functional features can be used for investigating brain…

神经元与认知 · 定量生物学 2026-02-16 Giorgio Dolci , Silvia Saglia , Lorenza Brusini , Vince D. Calhoun , Ilaria Boscolo Galazzo , Gloria Menegaz

EEG-based emotion recognition holds significant promise for objective diagnosis of mood disorders. Graph neural networks (GNNs) have emerged as the dominant paradigm for modeling inter-channel dependencies in EEG, yet existing approaches…

机器学习 · 计算机科学 2026-05-26 Ziyi Wang , Dongyang Kuang

This paper considers joint learning of multiple sparse Granger graphical models to discover underlying common and differential Granger causality (GC) structures across multiple time series. This can be applied to drawing group-level brain…

机器学习 · 计算机科学 2021-05-25 Parinthorn Manomaisaowapak , Jitkomut Songsiri

The causal relationships between biomarkers are essential for disease diagnosis and medical treatment planning. One notable application is Alzheimer's disease (AD) diagnosis, where certain biomarkers may influence the presence of others,…

信息检索 · 计算机科学 2025-06-13 Xiaofan Zhou , Liangjie Huang , Pinyang Cheng , Wenpen Yin , Rui Zhang , Wenrui Hao , Lu Cheng

Functional alterations in the relevant neural circuits occur from drug addiction over a certain period. And these significant alterations are also revealed by analyzing fMRI. However, because of fMRI's high dimensionality and poor…

图像与视频处理 · 电气工程与系统科学 2022-07-12 Changwei Gong , Changhong Jing , Junren Pan , Shuqiang Wang

Functional connectivity analysis is an important tool for characterizing interactions among brain regions, particularly in studies of neurodegenerative disorders such as Alzheimer's disease (AD). Gaussian graphical models (GGMs) provide a…

统计方法学 · 统计学 2026-04-14 Panpan Zhang , Shiying Xiao , W. Hudson Robb , Dandan Liu , Angela L. Jefferson , Jun Yan

Background: Alzheimer's disease and related dementias (ADRD) ranks as the sixth leading cause of death in the US, underlining the importance of accurate ADRD risk prediction. While recent advancement in ADRD risk prediction have primarily…

机器学习 · 计算机科学 2024-06-11 Xinyue Hu , Zenan Sun , Yi Nian , Yichen Wang , Yifang Dang , Fang Li , Jingna Feng , Evan Yu , Cui Tao

Substance use is a global issue that negatively impacts millions of persons who use drugs (PWUDs). In practice, identifying vulnerable PWUDs for efficient allocation of appropriate resources is challenging due to their complex use patterns…

The Granger framework is useful for discovering causal relations in time-varying signals. However, most Granger causality (GC) methods are developed for densely sampled timeseries data. A substantially different setting, particularly common…

机器学习 · 计算机科学 2024-12-19 Minh Nguyen , Gia H. Ngo , Mert R. Sabuncu

Graph-based retrieval-augmented generation (Graph-based RAG) has demonstrated significant potential in enhancing Large Language Models (LLMs) with structured knowledge. However, existing methods face three critical challenges: Inaccurate…

机器学习 · 计算机科学 2026-03-18 Yubo Wang , Haoyang Li , Fei Teng , Lei Chen

Granger causality is well established within the neurosciences for inference of directed functional connectivity from neurophysiological data. These data usually consist of time series which subsample a continuous-time biophysiological…

应用统计 · 统计学 2016-09-08 Lionel Barnett , Anil K. Seth

This paper is motivated by studies in neuroscience experiments to understand interactions between nodes in a brain network using different types of data modalities that capture different distinct facets of brain activity. To assess…

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by atypical brain connectivity. One of the crucial steps in addressing ASD is its early detection. This study introduces a novel computational framework that…

应用统计 · 统计学 2026-03-31 Abigail Kelly , Ramchandra Rimal , Arpan Sainju
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