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Its conceptual appeal and effectiveness has made latent factor modeling an indispensable tool for multivariate analysis. Despite its popularity across many fields, there are outstanding methodological challenges that have hampered practical…

统计方法学 · 统计学 2018-12-12 Kenichiro McAlinn , Veronika Rockova , Enakshi Saha

Missing data is a common problem in real-world settings and particularly relevant in healthcare applications where researchers use Electronic Health Records (EHR) and results of observational studies to apply analytics methods. This issue…

机器学习 · 统计学 2018-12-04 Dimitris Bertsimas , Agni Orfanoudaki , Colin Pawlowski

Modern large scale datasets are often plagued with missing entries. For tabular data with missing values, a flurry of imputation algorithms solve for a complete matrix which minimizes some penalized reconstruction error. However, almost…

机器学习 · 统计学 2021-01-20 Yuxuan Zhao , Madeleine Udell

Regular medical records are useful for medical practitioners to analyze and monitor patient health status especially for those with chronic disease, but such records are usually incomplete due to unpunctuality and absence of patients. In…

Exposure to air pollution is associated with increased morbidity and mortality. Recent technological advancements permit the collection of time-resolved personal exposure data. Such data are often incomplete with missing observations and…

Biomarkers are often measured in bulk to diagnose patients, monitor patient conditions, and research novel drug pathways. The measurement of these biomarkers often suffers from detection limits that result in missing and untrustworthy…

统计方法学 · 统计学 2023-06-13 Alton Barbehenn , Sihai Dave Zhao

In clinical trials, mixed effects models for repeated measures (MMRM) and pattern mixture models (PMM) are often used to analyze longitudinal continuous outcomes. We describe a simple missing data imputation algorithm for the MMRM that can…

统计方法学 · 统计学 2016-10-13 Yongqiang Tang

Structural transformation, the shift from agrarian economies to more diversified industrial and service-based systems, is a key driver of economic development. However, in low- and middle-income countries (LMICs), data scarcity and…

应用统计 · 统计学 2025-10-02 Ronald Katende

Defining the number of latent factors has been one of the most challenging problems in factor analysis. Infinite factor models offer a solution to this problem by applying increasing shrinkage on the columns of factor loading matrices, thus…

统计方法学 · 统计学 2023-09-25 Margarita Grushanina

Missing data are ubiquitous in the era of big data and, if inadequately handled, are known to lead to biased findings and have deleterious impact on data-driven decision makings. To mitigate its impact, many missing value imputation methods…

机器学习 · 计算机科学 2021-10-26 Yiliang Zhang , Qi Long

Imputation is a popular approach to handling censored, missing, and error-prone covariates -- all coarsened data types for which the true values are unknown. However, there are nuances to imputing these different data types based on the…

统计方法学 · 统计学 2025-04-29 Sarah C. Lotspeich , Ethan M. Alt

Derived variables are variables that are constructed from one or more source variables through established mathematical operations or algorithms. For example, body mass index (BMI) is a derived variable constructed from two source…

统计方法学 · 统计学 2025-03-24 Harlan Campbell , Tim Morris , Paul Gustafson

Purpose: Factor analysis (FA) has become part and parcel in metabolic syndrome (MBS) research. Both exploration- and confirmation-driven factor analyzes are rampant. However, factor analytic results on MBS differ widely. A situation that is…

应用统计 · 统计学 2016-09-09 Carel F. W. Peeters , James Dziura , Floryt van Wesel

Multimodal data, where different types of data are collected from the same subjects, are fast emerging in a large variety of scientific applications. Factor analysis is commonly used in integrative analysis of multimodal data, and is…

统计理论 · 数学 2021-03-31 Quefeng Li , Lexin Li

Real-time monitoring in modern medical research introduces functional longitudinal data, characterized by continuous-time measurements of outcomes, treatments, and confounders. This complexity leads to uncountably infinite…

统计方法学 · 统计学 2025-08-15 Andrew Ying

Microbiome `omics approaches can reveal intriguing relationships between the human microbiome and certain disease states. Along with the identification of specific bacteria taxa associated with diseases, recent scientific advancements…

应用统计 · 统计学 2019-10-07 Shuang Jiang , Guanghua Xiao , Andrew Y. Koh , Qiwei Li , Xiaowei Zhan

Missing values in high-dimensional, mixed-type datasets pose significant challenges for data imputation, particularly under Missing Not At Random (MNAR) mechanisms. Existing methods struggle to integrate local and global data…

机器学习 · 计算机科学 2025-11-13 Md Atik Ahamed , Qiang Ye , Qiang Cheng

Data analysis usually suffers from the Missing Not At Random (MNAR) problem, where the cause of the value missing is not fully observed. Compared to the naive Missing Completely At Random (MCAR) problem, it is more in line with the…

机器学习 · 计算机科学 2025-05-27 Jialei Chen , Yuanbo Xu , Pengyang Wang , Yongjian Yang

Economists are blessed with a wealth of data for analysis, but more often than not, values in some entries of the data matrix are missing. Various methods have been proposed to handle missing observations in a few variables. We exploit the…

计量经济学 · 经济学 2022-02-02 Ercument Cahan , Jushan Bai , Serena Ng

We develop a model-based methodology for integrating gene-set information with an experimentally-derived gene list. The methodology uses a previously reported sampling model, but takes advantage of natural constraints in the…

统计方法学 · 统计学 2015-06-02 Zhishi Wang , Qiuling He , Bret Larget , Michael A. Newton