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Learning good representation of giga-pixel level whole slide pathology images (WSI) for downstream tasks is critical. Previous studies employ multiple instance learning (MIL) to represent WSIs as bags of sampled patches because, for most…

计算机视觉与模式识别 · 计算机科学 2022-12-01 Chunyuan Li , Xinliang Zhu , Jiawen Yao , Junzhou Huang

Gigapixel image analysis, particularly for whole slide images (WSIs), often relies on multiple instance learning (MIL). Under the paradigm of MIL, patch image representations are extracted and then fixed during the training of the MIL…

计算机视觉与模式识别 · 计算机科学 2024-12-20 Kunming Tang , Zhiguo Jiang , Jun Shi , Wei Wang , Haibo Wu , Yushan Zheng

Multiple instance learning (MIL) significantly reduced annotation costs via bag-level weak labels for large-scale images, such as histopathological whole slide images (WSIs). However, its adaptability to continual tasks with minimal…

计算机视觉与模式识别 · 计算机科学 2025-07-09 Byung Hyun Lee , Wongi Jeong , Woojae Han , Kyoungbun Lee , Se Young Chun

Breast cancer is the most prevalent cancer in women worldwide. Histopathology image analysis serves as the gold standard for cancer diagnosis. In this regard, whole-slide imaging (WSI), a revolutionary technology in digital pathology,…

统计方法学 · 统计学 2026-04-21 Baichen Yu , Xuetong Li , Jing Zhou , Hansheng Wang

Large language models (LLMs) have shown promising capabilities in visually interpreting medical time-series data. However, their general-purpose design can limit domain-specific precision, and the proprietary nature of many models poses…

Whole slide image (WSI) classification requires repetitive zoom-in and out for pathologists, as only small portions of the slide may be relevant to detecting cancer. Due to the lack of patch-level labels, multiple instance learning (MIL) is…

计算机视觉与模式识别 · 计算机科学 2023-11-30 Seongho Keum , Sanghyun Kim , Soojeong Lee , Juho Lee

Weakly supervised whole slide image classification is usually formulated as a multiple instance learning (MIL) problem, where each slide is treated as a bag, and the patches cut out of it are treated as instances. Existing methods either…

计算机视觉与模式识别 · 计算机科学 2024-05-14 Linhao Qu , Yingfan Ma , Xiaoyuan Luo , Manning Wang , Zhijian Song

Multi-Instance Learning (MIL) is pivotal for analyzing complex, weakly labeled datasets, such as whole-slide images (WSIs) in computational pathology, where bags comprise unordered collections of instances with sparse diagnostic relevance.…

计算机视觉与模式识别 · 计算机科学 2025-09-16 Yuedi Zhang , Zhixiang Xia , Guosheng Yin , Bin Liu

Histology analysis of the tumor micro-environment integrated with genomic assays is the gold standard for most cancers in modern medicine. This paper proposes a Gene-induced Multimodal Pre-training (GiMP) framework, which jointly…

计算机视觉与模式识别 · 计算机科学 2023-09-07 Ting Jin , Xingran Xie , Renjie Wan , Qingli Li , Yan Wang

Weakly Supervised Object Detection (WSOD), using only image-level annotations to train object detectors, is of growing importance in object recognition. In this paper, we propose a novel deep network for WSOD. Unlike previous networks that…

计算机视觉与模式识别 · 计算机科学 2018-10-16 Peng Tang , Xinggang Wang , Song Bai , Wei Shen , Xiang Bai , Wenyu Liu , Alan Yuille

Whole Slide Images (WSIs) exhibit hierarchical structure, where diagnostic information emerges from cellular morphology, regional tissue organization, and global context. Existing Computational Pathology (CPath) Multimodal Large Language…

Digital pathology has revolutionized the field by enabling the digitization of tissue samples into whole slide images (WSIs). However, the high resolution and large size of WSIs present significant challenges when it comes to applying Deep…

计算机视觉与模式识别 · 计算机科学 2025-07-03 Ali Mammadov , Loïc Le Folgoc , Guillaume Hocquet , Pietro Gori

Since the emergence of the ImageNet dataset, the pretraining and fine-tuning approach has become widely adopted in computer vision due to the ability of ImageNet-pretrained models to learn a wide variety of visual features. However, a…

计算机视觉与模式识别 · 计算机科学 2024-10-22 Pablo Meseguer , Rocío del Amor , Adrian Colomer , Valery Naranjo

Whole slide pathology image classification presents challenges due to gigapixel image sizes and limited annotation labels, hindering model generalization. This paper introduces a prompt learning method to adapt large vision-language models…

The whole slide histopathology images (WSIs) play a critical role in gastric cancer diagnosis. However, due to the large scale of WSIs and various sizes of the abnormal area, how to select informative regions and analyze them are quite…

计算机视觉与模式识别 · 计算机科学 2020-10-14 Shujun Wang , Yaxi Zhu , Lequan Yu , Hao Chen , Huangjing Lin , Xiangbo Wan , Xinjuan Fan , Pheng-Ann Hen

Cancer survival prediction is a challenging task that involves analyzing of the tumor microenvironment within Whole Slide Image (WSI). Previous methods cannot effectively capture the intricate interaction features among instances within the…

计算机视觉与模式识别 · 计算机科学 2024-10-23 Zekang Yang , Hong Liu , Xiangdong Wang

Computer-aided pathology diagnosis based on the classification of Whole Slide Image (WSI) plays an important role in clinical practice, and it is often formulated as a weakly-supervised Multiple Instance Learning (MIL) problem. Existing…

计算机视觉与模式识别 · 计算机科学 2022-10-11 Linhao Qu , Xiaoyuan Luo , Manning Wang , Zhijian Song

Whole Slide Images (WSIs) are giga-pixel in scale and are typically partitioned into small instances in WSI classification pipelines for computational feasibility. However, obtaining extensive instance level annotations is costly, making…

计算机视觉与模式识别 · 计算机科学 2026-03-24 Jayanie Bogahawatte , Sachith Seneviratne , Saman Halgamuge

Survival prediction using whole-slide images (WSIs) is crucial in cancer re-search. Despite notable success, existing approaches are limited by their reliance on sparse slide-level labels, which hinders the learning of discriminative…

计算机视觉与模式识别 · 计算机科学 2025-07-08 Jiaqi Cui , Lu Wen , Yuchen Fei , Bo Liu , Luping Zhou , Dinggang Shen , Yan Wang

Multi-view learning (MVL) has gained great success in integrating information from multiple perspectives of a dataset to improve downstream task performance. To make MVL methods more practical in an open-ended environment, this paper…

机器学习 · 计算机科学 2023-10-16 Depeng Li , Tianqi Wang , Junwei Chen , Kenji Kawaguchi , Cheng Lian , Zhigang Zeng