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The challenging problem of conducting fully Bayesian inference for the reaction rate constants governing stochastic kinetic models (SKMs) is considered. Given the challenges underlying this problem, the Markov jump process representation is…

统计计算 · 统计学 2019-01-10 Andrew Golightly , Emma Bradley , Tom Lowe , Colin S. Gillespie

In this paper we utilize a survival analysis methodology incorporating Bayesian additive regression trees to account for nonlinear and additive covariate effects. We compare the performance of Bayesian additive regression trees, Cox…

应用统计 · 统计学 2019-11-05 Satabdi Saha , Duchwan Ryu , Nader Ebrahimi

Restricted mean survival time (RMST) is an intuitive summary statistic for time-to-event random variables, and can be used for measuring treatment effects. Compared to hazard ratio, its estimation procedure is robust against the…

统计方法学 · 统计学 2023-05-25 Ruizhe Chen , Sanjib Basu , Qian Shi

Bayesian estimation approaches, which are capable of combining the information of experimental data from different likelihood functions to achieve high precisions, have been widely used in phase estimation via introducing a controllable…

量子物理 · 物理学 2021-07-02 Yuxiang Qiu , Min Zhuang , Jiahao Huang , Chaohong Lee

In emergency response and other high-stakes societal applications, early-stage state estimates critically shape downstream outcomes. Yet, these initial state estimates-often based on limited or biased information-can be severely misaligned…

机器学习 · 计算机科学 2026-01-28 Yiwei Shi , Hongnan Ma , Mengyue Yang , Cunjia Liu , Weiru Liu

Methods for estimating heterogeneous treatment effect in observational data have largely focused on continuous or binary outcomes, and have been relatively less vetted with survival outcomes. Using flexible machine learning methods in the…

应用统计 · 统计学 2021-07-09 Liangyuan Hu , Jiayi Ji , Fan Li

In this work, we study the problem of clustering survival data $-$ a challenging and so far under-explored task. We introduce a novel semi-supervised probabilistic approach to cluster survival data by leveraging recent advances in…

Treatment specific survival curves are an important tool to illustrate the treatment effect in studies with time-to-event outcomes. In non-randomized studies, unadjusted estimates can lead to biased depictions due to confounding. Multiple…

统计方法学 · 统计学 2023-04-25 Robin Denz , Renate Klaaßen-Mielke , Nina Timmesfeld

A quality-Bayesian approach, combining the direct sampling method and the Bayesian inversion, is proposed to reconstruct the locations and intensities of the unknown acoustic sources using partial data. First, we extend the direct sampling…

数值分析 · 数学 2020-04-10 Zhaoxing Li , Yanfang Liu , Jiguang Sun , Liwei Xu

A Bayesian non-parametric framework for studying time-to-event data is proposed, where the prior distribution is allowed to depend on an additional random source, and may update with the sample size. Such scenarios are natural, for…

统计方法学 · 统计学 2025-05-06 Martin Bladt , Jorge González Cázares

We propose a novel methodology to quantify the effect of stochastic interventions on non-terminal time-to-events that lie on the pathway between an exposure and a terminal time-to-event outcome. Investigating these effects is particularly…

统计方法学 · 统计学 2024-07-17 Linda Valeri , Cécile Proust-Lima , Weijia Fan , Jarvis T. Chen , Hélène Jacqmin-Gadda

Relational learning can be used to augment one data source with other correlated sources of information, to improve predictive accuracy. We frame a large class of relational learning problems as matrix factorization problems, and propose a…

机器学习 · 计算机科学 2012-03-19 Ajit P. Singh , Geoffrey Gordon

This paper proposes a new statistical approach for assessing treatment effect using Bayesian Networks (BNs). The goal is to draw causal inferences from observational data with a binary outcome and discrete covariates. The BNs are here used…

In this article, we particularly address the problem of assessing the impact of clinical stage and age on the specific survival times of men with breast cancer when cure is a possibility, where there is also the interest of explaining this…

统计方法学 · 统计学 2021-05-11 Agatha Rodrigues , Patrick Borges , Bruno Santos

In almost all situation assessment problems, it is useful to dynamically contract and expand the states under consideration as assessment proceeds. Contraction is most often used to combine similar events or low probability events together…

人工智能 · 计算机科学 2013-04-05 Kuo-Chu Chang , Robert Fung

An emerging challenge for time-to-event data is studying semi-competing risks, namely when two event times are of interest: a non-terminal event time (e.g. age at disease diagnosis), and a terminal event time (e.g. age at death). The…

统计方法学 · 统计学 2020-10-12 Daniel Nevo , Malka Gorfine

In epidemiological surveys, data missing not at random (MNAR) due to survey nonresponse may potentially lead to a bias in the risk factor estimates. We propose an approach based on Bayesian data augmentation and survival modelling to reduce…

统计方法学 · 统计学 2017-08-29 Juho Kopra , Juha Karvanen , Tommi Härkänen

To draw real-world evidence about the comparative effectiveness of multiple time-varying treatments on patient survival, we develop a joint marginal structural survival model and a novel weighting strategy to account for time-varying…

统计方法学 · 统计学 2023-08-08 Liangyuan Hu , Jiayi Ji , Himanshu Joshi , Erick Scott , Fan Li

Bayesian methods are critical for quantifying the behaviors of systems. They capture our uncertainty about a system's behavior using probability distributions and update this understanding as new information becomes available. Probabilistic…

统计计算 · 统计学 2018-04-25 Thomas A. Catanach , James L. Beck

We study objective Bayesian inference for linear regression models with residual errors distributed according to the class of two-piece scale mixtures of normal distributions. These models allow for capturing departures from the usual…

应用统计 · 统计学 2016-05-09 F. J. Rubio , K. Yu
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