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A new delivery option for cancer centers equipped with linear accelerators fitted with multi-leaf collimators (MLC) -- i.e. centers which can perform intensity modulated radiation therapy (IMRT) -- is rotational delivery. In rotational…

医学物理 · 物理学 2009-10-27 David Craft , Thomas Bortfeld

Temporally modulated pulsed radiotherapy (TMPRT) delivers conventional fraction doses of radiation using temporally separated pulses of low doses (<30 cGy) yielding fraction-effective dose rates of around 6.7 cGy/min with the goal to…

医学物理 · 物理学 2026-01-13 Christian Velten , Adam Bayliss , Jiayi Huang , Wolfgang A. Tomé

Background: Real-time treatment planning in IMRT is challenging due to complex beam interactions. AI has improved automation, but existing models require large, high-quality datasets and lack universal applicability. Deep reinforcement…

医学物理 · 物理学 2025-02-26 Md Mainul Abrar , Parvat Sapkota , Damon Sprouts , Xun Jia , Yujie Chi

Purpose: Patient-specific ridge filters can modulate proton energy to obtain a conformal dose. We describe a new framework for optimization of filter design and spot maps to meet the unique demands of FLASH radiotherapy. We demonstrate an…

Objective: Radiation therapy treatment planning is a time-consuming process involving iterative adjustments of hyperparameters. To automate the treatment planning process, we propose a meta-optimization framework, called MetaPlanner (MP).…

医学物理 · 物理学 2022-02-22 Charles Huang , Yusuke Nomura , Yong Yang , Lei Xing

The NP-hard problem of task scheduling with communication delays (P|prec,c_{ij}|C_{\mathrm{max}}) is often tackled using approximate methods, but guarantees on the quality of these heuristic solutions are hard to come by. Optimal schedules…

分布式、并行与集群计算 · 计算机科学 2019-01-23 Michael Orr , Oliver Sinnen

Split Learning (SL) is a promising Distributed Learning approach in electromyography (EMG) based prosthetic control, due to its applicability within resource-constrained environments. Other learning approaches, such as Deep Learning and…

机器学习 · 计算机科学 2024-05-14 Matea Marinova , Daniel Denkovski , Hristijan Gjoreski , Zoran Hadzi-Velkov , Valentin Rakovic

Robots are widely used in industry due to their efficiency and high accuracy in performance. One of the most intriguing issues in manufacturing stage of production line is to minimize significantly high percentage of energy consumed by…

机器人学 · 计算机科学 2018-06-26 Sourya Dipta Das , Victor Bain , Pratyusha Rakshit

Radiation therapy (RT) is a medical treatment to kill cancer cells or shrink tumors. To manually schedule patients for RT is a time-consuming and challenging task. By the use of optimization, patient schedules for RT can be created…

最优化与控制 · 数学 2023-05-04 Sara Frimodig , Per Enqvist , Mats Carlsson , Carole Mercier

Objective: Radiotherapy treatment planning is a time-consuming and potentially subjective process that requires the iterative adjustment of model parameters to balance multiple conflicting objectives. Recent advancements in frontier…

The development of ultra-intense laser-based sources of high energy ions is an important goal, with a variety of potential applications. One of the barriers to achieving this goal is the need to maximize the conversion efficiency from laser…

The purpose of this study was to use various dosimetrical indices to determine the best IMRT modality technique for treating patients with prostate cancer. Ten patients with prostate cancer were included in this study. Intensity modulated…

Purpose:The recently proposed IPO-IMPT framework allows simultaneous optimization of dose, dose rate, and LET for FLASH treatment planning. Finding solutions to IPO-IMPT is difficult due to computational intensiveness. Nevertheless, an…

Radiotherapy (RT) is a critical cancer treatment, with volumetric modulated arc therapy (VMAT) being a commonly used technique that enhances dose conformity by dynamically adjusting multileaf collimator (MLC) positions and monitor units…

医学物理 · 物理学 2025-06-26 Stefanos Achlatis , Efstratios Gavves , Jan-Jakob Sonke

In modern deep learning models, long training times and large datasets present significant challenges to both efficiency and scalability. Effective data curation and sample selection are crucial for optimizing the training process of deep…

机器学习 · 计算机科学 2024-12-24 Mohammadreza Sharifi

In proton therapy of low-grade glioma (LGG) patients, contrast-enhancing brain lesions (CEBLs) on magnetic resonance imaging are considered predictive of late radiation-induced lesions. From the observation that CEBLs tend to concentrate in…

医学物理 · 物理学 2026-04-16 Tim Ortkamp , Habiba Sallem , Semi Harrabi , Martin Frank , Oliver Jäkel , Julia Bauer , Niklas Wahl

The opportunistic routing has advantages on improving the packet delivery ratio between source node and candidate set (PDRsc). However, considering the frequent topology variation in wireless sensor networks, how to improve and control the…

网络与互联网体系结构 · 计算机科学 2017-10-02 Ning Li , Jose-Fernan Martinez-Ortega , Vicente Hernandez Diaz

Background: Radiotherapy treatment planning involves solving large-scale optimization problems that are often approximated and solved sub-optimally due to time constraints. Central to these problems is the dose influence matrix which…

医学物理 · 物理学 2024-10-02 Mojtaba Tefagh , Gourav Jhanwar , Masoud Zarepisheh

Laser acceleration promises innovation in particle beam therapy of cancer where an ultra-compact accelerator system for cancer beam therapy can become affordable to a broad range of patients. This is not feasible without the introduction of…

Adapting models pre-trained on large-scale datasets is a proven way to reach strong performance quickly for down-stream tasks. However, the growth of state-of-the-art mod-els makes traditional full fine-tuning unsuitable and difficult,…

计算机视觉与模式识别 · 计算机科学 2026-03-24 Maxime Fontana , Michael Spratling , Miaojing Shi