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DNA sequencing is revolutionising the field of medicine. DNA sequencers, the machines which perform DNA sequencing, have evolved from the size of a fridge to that of a mobile phone over the last two decades. The cost of sequencing a human…

基因组学 · 定量生物学 2021-01-14 Hasindu Gamaarachchi

Quantitative cancer image analysis relies on the accurate delineation of tumours, a very specialised and time-consuming task. For this reason, methods for automated segmentation of tumours in medical imaging have been extensively developed…

图像与视频处理 · 电气工程与系统科学 2022-12-07 Saúl Alonso-Monsalve , Leigh H. Whitehead , Adam Aurisano , Lorena Escudero Sanchez

Understanding the structural growth of paediatric brains is a key step in the identification of various neuro-developmental disorders. However, our knowledge is limited by many factors, including the lack of automated image analysis tools,…

图像与视频处理 · 电气工程与系统科学 2024-10-10 Vaanathi Sundaresan , Nicola K Dinsdale

Background Computer-based geometrical meshes of bones are important for applications in computational biomechanics as well as clinical software. There is however a lack of freely available detailed bone meshes, especially related to the…

组织与器官 · 定量生物学 2018-07-16 Manish Sreenivasa , Daniel Gonzalez-Alvarado

A unified deep neural network, denoted the multi-scale CNN (MS-CNN), is proposed for fast multi-scale object detection. The MS-CNN consists of a proposal sub-network and a detection sub-network. In the proposal sub-network, detection is…

计算机视觉与模式识别 · 计算机科学 2016-07-26 Zhaowei Cai , Quanfu Fan , Rogerio S. Feris , Nuno Vasconcelos

Analysis of microscope images is a tedious work which requires patience and time, usually done manually by the microscopist after data collection. Here we introduce an approach of automatic image analysis, which is based on locally applied…

图像与视频处理 · 电气工程与系统科学 2019-12-17 Benedykt R. Jany , Arkadiusz Janas , Franciszek Krok

Analysis of three-dimensional biological samples is critical to understanding tissue function and the mechanisms of disease. Many chronic conditions, like neurodegenerative diseases and cancers, correlate with complex tissue changes that…

生物物理 · 物理学 2019-11-06 Jiaming Guo , Camille Artur , Jason L. Eriksen , David Mayerich

X-ray computed tomography (XCT) is an important tool for high-resolution non-destructive characterization of additively-manufactured metal components. XCT reconstructions of metal components may have beam hardening artifacts such as cupping…

The ever-increasing volumes of scientific data present new challenges for distributed computing and Grid technologies. The emerging Big Data revolution drives exploration in scientific fields including nanotechnology, astrophysics,…

分布式、并行与集群计算 · 计算机科学 2019-08-14 A. V. Vaniachine

The field of connectomics faces unprecedented "big data" challenges. To reconstruct neuronal connectivity, automated pixel-level segmentation is required for petabytes of streaming electron microscopy data. Existing algorithms provide…

Technological advancements in modern scientific instruments, such as scanning electron microscopes (SEMs), have significantly increased data acquisition rates and image resolutions enabling new questions to be explored; however, the…

图像与视频处理 · 电气工程与系统科学 2022-02-24 Maksim Levental , Ryan Chard , Kyle Chard , Ian Foster , Gregg A. Wildenberg

Permeability characterizes the capacity of porous formations to conduct fluids, thereby governing the performance of carbon capture, utilization, and storage (CCUS), hydrocarbon extraction, and subsurface energy storage. A reliable…

Parallelism patterns (e.g., map or reduce) have proven to be effective tools for parallelizing high-performance applications. In this paper, we study the recursive registration of a series of electron microscopy images - a time consuming…

分布式、并行与集群计算 · 计算机科学 2020-10-26 Marcin Copik , Tobias Grosser , Torsten Hoefler , Paolo Bientinesi , Benjamin Berkels

Atom probe tomography (APT) has matured to a versatile nanoanalytical characterization tool with applications that range from materials science to geology and possibly beyond. Already, well over 100 APT microscopes exist worldwide.…

计算物理 · 物理学 2020-04-14 Markus Kühbach , Priyanshu Bajaj , Murat Han Celik , Eric Aimo Jägle , Baptiste Gault

Field-of-view and resolution trade-offs in X-Ray micro-computed tomography (micro-CT) imaging limit the characterization, analysis and model development of multi-scale porous systems. To this end, we developed an applied methodology…

地球物理 · 物理学 2022-03-17 Samuel J. Jackson , Yufu Niu , Sojwal Manoorkar , Peyman Mostaghimi , Ryan T. Armstrong

The use of nuclear emulsions to record tracks of charged particles with an accuracy of better than 1 micron is possible in large physics experiments thanks to the recent improvements in the industrial production of emulsions and to the…

仪器与探测器 · 物理学 2008-11-26 G. Sirri

The complexity of human biology and its intricate systems holds immense potential for advancing human health, disease treatment, and scientific discovery. However, traditional manual methods for studying biological interactions are often…

其他定量生物学 · 定量生物学 2025-01-24 Himanshu Buckchash , Gyanendra Kumar Verma , Dilip K. Prasad

Robotic-assisted Minimally Invasive Surgery (RMIS) can benefit from the automation of common, repetitive or well-defined but ergonomically difficult tasks. One such task is the scanning of a pick-up endomicroscopy probe over a complex,…

机器人学 · 计算机科学 2018-03-05 Lin Zhang , Menglong Ye , Petros Giataganas , Michael Hughes , Guang-Zhong Yang

Nowadays, Machine Learning (ML) is experiencing tremendous popularity that has never been seen before. The operationalization of ML models is governed by a set of concepts and methods referred to as Machine Learning Operations (MLOps).…

机器学习 · 计算机科学 2023-10-05 Angelo Yamachui Sitcheu , Nils Friederich , Simon Baeuerle , Oliver Neumann , Markus Reischl , Ralf Mikut

Brain mapping research in most neuroanatomical laboratories relies on conventional processing techniques, which often introduce histological artifacts such as tissue tears and tissue loss. In this paper we present techniques and algorithms…

图形学 · 计算机科学 2017-12-29 Nitin Agarwal , Xiangmin Xu , Gopi Meenakshisundaram