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Sepsis is a life-threatening and serious global health issue. This study combines knowledge with available hospital data to investigate the potential causes of Sepsis that can be affected by policy decisions. We investigate the underlying…

机器学习 · 计算机科学 2025-02-19 Bruno Petrungaro , Neville K. Kitson , Anthony C. Constantinou

Human brains lie at the core of complex neurobiological systems, where the neurons, circuits, and subsystems interact in enigmatic ways. Understanding the structural and functional mechanisms of the brain has long been an intriguing pursuit…

神经元与认知 · 定量生物学 2022-07-26 Hejie Cui , Wei Dai , Yanqiao Zhu , Xiaoxiao Li , Lifang He , Carl Yang

Edge detection (ED) is a fundamental perceptual process in computer vision, forming the structural basis for high-level reasoning tasks such as segmentation, recognition, and scene understanding. Despite substantial progress achieved by…

计算机视觉与模式识别 · 计算机科学 2026-02-12 Hao Shu

Unsupervised attributed graph representation learning is challenging since both structural and feature information are required to be represented in the latent space. Existing methods concentrate on learning latent representation via…

机器学习 · 计算机科学 2021-04-28 Zelin Zang , Siyuan Li , Di Wu , Jianzhu Guo , Yongjie Xu , Stan Z. Li

Understanding disease-gene associations is essential for unravelling disease mechanisms and advancing diagnostics and therapeutics. Traditional approaches based on manual curation and literature review are labour-intensive and not scalable,…

机器学习 · 计算机科学 2026-02-24 Osman Onur Kuzucu , Tunca Doğan

Transformer-based deep learning models have shown promise for disease risk prediction using electronic health records(EHRs), but modeling temporal dependencies remains a key challenge due to irregular visit intervals and lack of uniform…

机器学习 · 计算机科学 2025-11-10 Daniel S. Lee , Mayra S. Haedo-Cruz , Chen Jiang , Oshin Miranda , LiRong Wang

Knowledge graphs represent real-world entities and their relations in a semantically-rich structure supported by ontologies. Exploring this data with machine learning methods often relies on knowledge graph embeddings, which produce latent…

机器学习 · 计算机科学 2023-06-23 Rita T. Sousa , Sara Silva , Catia Pesquita

Today's densely instrumented world offers tremendous opportunities for continuous acquisition and analysis of multimodal sensor data providing temporal characterization of an individual's behaviors. Is it possible to efficiently couple such…

机器学习 · 计算机科学 2018-09-03 Homa Hosseinmardi , Amir Ghasemian , Shrikanth Narayanan , Kristina Lerman , Emilio Ferrara

Embedding a web-scale information network into a low-dimensional vector space facilitates tasks such as link prediction, classification, and visualization. Past research has addressed the problem of extracting such embeddings by adopting…

社会与信息网络 · 计算机科学 2018-03-14 Anton Tsitsulin , Davide Mottin , Panagiotis Karras , Emmanuel Müller

Motivated by the need to study the molecular mechanism underlying Type 1 Diabetes (T1D) with the gene expression data collected from both the patients and healthy controls at multiple time points, we propose an innovative method for jointly…

统计方法学 · 统计学 2018-12-10 Bochao Jia , Faming Liang , the TEDDY Study Group

Rule mining on knowledge graphs allows for explainable link prediction. Contrarily, embedding-based methods for link prediction are well known for their generalization capabilities, but their predictions are not interpretable. Several…

人工智能 · 计算机科学 2024-06-17 N'Dah Jean Kouagou , Arif Yilmaz , Michel Dumontier , Axel-Cyrille Ngonga Ngomo

The development of models for multiple heterogeneous network data is of critical importance both in statistical network theory and across multiple application domains. Although single-graph inference is well-studied, multiple graph…

统计方法学 · 统计学 2020-08-25 Jesús Arroyo , Avanti Athreya , Joshua Cape , Guodong Chen , Carey E. Priebe , Joshua T. Vogelstein

Current methods for detecting spurious correlations rely on analyzing dataset statistics or error patterns, leaving many harmful shortcuts invisible when counterexamples are absent. We introduce BEE (Bridging Explainability and Embeddings),…

Graph embedding provides an efficient solution for graph analysis by converting the graph into a low-dimensional space which preserves the structure information. In contrast to the graph structure data, the i.i.d. node embedding can be…

机器学习 · 计算机科学 2017-05-16 Hongyun Cai , Vincent W. Zheng , Kevin Chen-Chuan Chang

Biomedical research has revealed the crucial role of miRNAs in the progression of many diseases, and computational prediction methods are increasingly proposed for assisting biological experiments to verify miRNA-disease associations…

计算工程、金融与科学 · 计算机科学 2023-08-29 Yi Zhou , Meixuan Wu , Chengzhou Ouyang , Min Zhu

Survival analysis, as a challenging task, requires integrating Whole Slide Images (WSIs) and genomic data for comprehensive decision-making. There are two main challenges in this task: significant heterogeneity and complex inter- and…

图像与视频处理 · 电气工程与系统科学 2024-06-17 Conghao Xiong , Hao Chen , Hao Zheng , Dong Wei , Yefeng Zheng , Joseph J. Y. Sung , Irwin King

Graph node embedding aims at learning a vector representation for all nodes given a graph. It is a central problem in many machine learning tasks (e.g., node classification, recommendation, community detection). The key problem in graph…

机器学习 · 计算机科学 2019-10-01 Shupeng Gui , Xiangliang Zhang , Pan Zhong , Shuang Qiu , Mingrui Wu , Jieping Ye , Zhengdao Wang , Ji Liu

The embedding of Biomedical Knowledge Graphs (BKGs) generates robust representations, valuable for a variety of artificial intelligence applications, including predicting drug combinations and reasoning disease-drug relationships.…

数据库 · 计算机科学 2023-10-17 Zhiguang Fan , Yuedong Yang , Mingyuan Xu , Hongming Chen

Causal inference in observational studies with high-dimensional covariates presents significant challenges. We introduce CausalBGM, an AI-powered Bayesian generative modeling approach that captures the causal relationship among covariates,…

机器学习 · 统计学 2026-02-23 Qiao Liu , Wing Hung Wong

Link prediction (inferring missing or future connections between nodes in a graph) is a fundamental problem in network science with widespread applications in, e.g., biological systems, recommender systems, finance and cybersecurity. The…

机器学习 · 计算机科学 2026-05-12 Riccardo Porcedda , Francesca Chiaromonte , Fabrizio Lillo , Andrea Vandin