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Models for dependent data are distinguished by their targets of inference. Marginal models are useful when interest lies in quantifying associations averaged across a population of clusters. When the functional form of a covariate-outcome…

统计方法学 · 统计学 2022-04-18 Glen McGee , Alex Stringer

The joint analysis of biomedical data in Alzheimer's Disease (AD) is important for better clinical diagnosis and to understand the relationship between biomarkers. However, jointly accounting for heterogeneous measures poses important…

统计方法学 · 统计学 2018-08-14 Luigi Antelmi , Nicholas Ayache , Philippe Robert , Marco Lorenzi

Normative modelling is an emerging method for understanding the underlying heterogeneity within brain disorders like Alzheimer Disease (AD) by quantifying how each patient deviates from the expected normative pattern that has been learned…

图像与视频处理 · 电气工程与系统科学 2026-02-06 Sayantan Kumar , Philip Payne , Aristeidis Sotiras

Federated learning (FL) offers a privacy-centric distributed learning framework, enabling model training on individual clients and central aggregation without necessitating data exchange. Nonetheless, FL implementations often suffer from…

人工智能 · 计算机科学 2024-05-13 Rongyu Zhang , Yun Chen , Chenrui Wu , Fangxin Wang , Bo Li

We propose a model for diagnosing Autism spectrum disorder (ASD) using multimodal magnetic resonance imaging (MRI) data. Our approach integrates brain connectivity data from diffusion tensor imaging (DTI) and functional MRI (fMRI),…

神经元与认知 · 定量生物学 2024-10-10 Lu Wei , Yi Huang , Guosheng Yin , Fode Zhang , Manxue Zhang , Bin Liu

In neuroimaging data analysis, Gaussian graphical models are often used to model statistical dependencies across spatially remote brain regions known as functional connectivity. Typically, data is collected across a cohort of subjects and…

机器学习 · 统计学 2015-12-08 Ricardo Pio Monti , Christoforos Anagnostopoulos , Giovanni Montana

The identification of factors associated with mental and behavioral disorders in early childhood is critical both for psychopathology research and the support of primary health care practices. Motivated by the Millennium Cohort Study, in…

统计方法学 · 统计学 2021-09-15 Luca Merlo , Lea Petrella , Nikos Tzavidis

In this paper, we develop a finite mixture of convolutional distributions, a statistical model to analyze continuous data distributed approximately on a mixture of low-dimensional affine subspaces. The observations are assumed independent…

统计理论 · 数学 2026-04-21 Sunrit Chakraborty , XuanLong Nguyen

Mixed spatial autoregressive (SAR) models with numerical covariates have been well studied. However, as non-numerical data, such as functional data and compositional data, receive substantial amounts of attention and are applied to…

应用统计 · 统计学 2018-11-08 Huiwen Wang , Tingting Huang , Shanshan Wang

Covariate adjustment is an approach to improve the precision of trial analyses by adjusting for baseline variables that are prognostic of the primary endpoint. Motivated by the SEARCH Universal HIV Test-and-Treat Trial (2013-2017), we tell…

统计方法学 · 统计学 2025-12-16 Laura B. Balzer , Mark J. van der Laan , Maya L. Petersen

Federated learning is a distributed paradigm that allows multiple parties to collaboratively train deep models without exchanging the raw data. However, the data distribution among clients is naturally non-i.i.d., which leads to severe…

机器学习 · 计算机科学 2023-01-31 Tianfei Zhou , Ender Konukoglu

Jointly identifying a mixture of discrete and continuous factors of variability without supervision is a key problem in unraveling complex phenomena. Variational inference has emerged as a promising method to learn interpretable mixture…

机器学习 · 计算机科学 2021-04-14 Yeganeh M. Marghi , Rohan Gala , Uygar Sümbül

Autism spectrum disorder (ASD) represents a neurodevelopmental condition characterized by difficulties in expressing emotions and communication, particularly during early childhood. Understanding the affective state of children at an early…

计算机视觉与模式识别 · 计算机科学 2026-01-28 Aura Loredana Dan

Understanding how adult humans learn non-native speech categories such as tone information has shed novel insights into the mechanisms underlying experience-dependent brain plasticity. Scientists have traditionally examined these questions…

统计方法学 · 统计学 2020-06-16 Giorgio Paulon , Fernando Llanos , Bharath Chandrasekaran , Abhra Sarkar

Diagnosing Autism Spectrum Disorder (ASD) is a challenging problem, and is based purely on behavioral descriptions of symptomology (DSM-5/ICD-10), and requires informants to observe children with disorder across different settings (e.g.…

神经元与认知 · 定量生物学 2020-03-04 Taban Eslami , Joseph S. Raiker , Fahad Saeed

In this article, we propose a penalized clustering method for large scale data with multiple covariates through a functional data approach. In the proposed method, responses and covariates are linked together through nonparametric…

统计方法学 · 统计学 2008-01-17 Ping Ma , Wenxuan Zhong

Federated Learning offers a solution for decentralised model training, addressing the difficulties associated with distributed data and privacy in machine learning. However, the fact of data heterogeneity in federated learning frequently…

机器学习 · 计算机科学 2025-09-10 Ozgu Goksu , Nicolas Pugeault

Autism spectrum disorder (ASD) has been associated with structural alterations across cortical and subcortical regions. Quantitative neuroimaging enables large-scale analysis of these neuroanatomical patterns. This project used structural…

神经元与认知 · 定量生物学 2025-12-30 Ashley Chen

Neuroscientific research has revealed that the complex brain network can be organized into distinct functional communities, each characterized by a cohesive group of regions of interest (ROIs) with strong interconnections. These communities…

神经元与认知 · 定量生物学 2024-03-14 Yanting Yang , Beidi Zhao , Zhuohao Ni , Yize Zhao , Xiaoxiao Li

The joint alignment of multivariate functional data plays an important role in various fields such as signal processing, neuroscience and medicine, including the statistical analysis of data from wearable devices. Traditional methods often…

信号处理 · 电气工程与系统科学 2023-12-18 Vi Thanh Pham , Jonas Bille Nielsen , Klaus Fuglsang Kofoed , Jørgen Tobias Kühl , Andreas Kryger Jensen